STOM and SFXN5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		STOM	SFXN5
Description		stomatin	sideroflexin 5
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Mitochondrion Endoplasmic Reticulum Cytosol Cytoskeleton Plasma Membrane Membrane Cytoplasmic Vesicle Vesicle Azurophil Granule Membrane Specific Granule Membrane Melanosome Membrane Raft Perinuclear Region Of Cytoplasm Extracellular Exosome Tertiary Granule Membrane Blood Microparticle	Mitochondrion Mitochondrial Inner Membrane Membrane
	Molecular Function	Protein Binding Ion Channel Inhibitor Activity Identical Protein Binding Protein Homodimerization Activity RNA Polymerase Binding	Protein Binding Monoatomic Ion Transmembrane Transporter Activity Citrate Transmembrane Transporter Activity
	Biological Process	Regulation Of Monoatomic Ion Transmembrane Transport Host-mediated Activation Of Viral Genome Replication Positive Regulation Of Viral Process Positive Regulation Of Protein Targeting To Membrane	Monoatomic Ion Transport Amino Acid Transport Citrate Transport Monoatomic Ion Transmembrane Transport Transmembrane Transport Positive Regulation Of Cold-induced Thermogenesis Mitochondrial Transmembrane Transport
Pathways		Stimuli-sensing channels Neutrophil degranulation RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle RHOQ GTPase cycle RHOH GTPase cycle RHOJ GTPase cycle
Drugs
Diseases		Hereditary stomatocytosis (HSt); Dehydrated hereditary stomatocytosis (DHS); Overhydrated hereditary stomatocytosis (OHS); Familial pseudohyperkalemia (FP)
GWAS			Breast milk fatty acid composition (maternal genotype effect) ( 29514873) Malaria ( 31844061) Non-word reading ( 30741946) Schizophrenia ( 30285260)
Interacting Genes		81 interacting genes: AIG1 APOA2 ASIC1 ASIC2 ASIC3 ATP1B3 ATP6V0B ATP6V0C BCL2L2 BNIP1 C2 C3orf52 CFHR5 CHST1 CLDN19 CLRN2 CMTM5 CNIH3 CTXN3 CYB5B CYB5R3 DAGLA DVL3 EMP1 ERG28 FAXDC2 FUNDC2 GIMAP1 GIMAP5 GPR25 GPR37L1 GRM2 HMOX2 KCNK1 KTN1 LANCL1 LNPEP MGLL MMP14 NKG7 ORMDL1 PEDS1-UBE2V1 PEMT PGA4 PMP22 PTCH1 RPL13A RPRM RTP2 RUVBL1 RUVBL2 SCD SELENOK SERP2 SFT2D1 SFT2D2 SFXN1 SFXN5 SLC2A1 SLC35B4 SMCO4 STX6 TECR THSD7B TMEM109 TMEM120B TMEM140 TMEM14B TMEM203 TMEM208 TMEM254 TMEM60 TMEM86B TMEM98 TMPO TNF TNFRSF10C TSPO2 VAMP4 WFDC2 YIPF6	9 interacting genes: APOL2 AQP6 CREB3L1 EBP ERGIC3 STOM TMEM237 TMEM86B TMPPE
Entrez ID		2040	94097
HPRD ID		00585	18047
Ensembl ID		ENSG00000148175	ENSG00000144040
Uniprot IDs		F8VSL7 P27105	B4DIJ8 B8ZZJ6 Q8TD22
PDB IDs		7WH3
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Sensory Perception Of Sour Taste Endoplasmic Reticulum Response To Acidic PH Sodium Channel Activity PH-gated Sodium Channel Activity Monoatomic Ion-gated Channel Activity Ligand-gated Sodium Channel Activity Protein Binding Cellular Response To Type II Interferon Response To PH PH-gated Monoatomic Ion Channel Activity Nitric-oxide Synthase Complex Synaptic Vesicle To Endosome Fusion Mitochondrial Outer Membrane Response To Type II Interferon Proton-transporting Two-sector ATPase Complex, Proton-transporting Domain Nitrite Reductase (NO-forming) Activity R2TP Complex Cellular Response To PH Detection Of Mechanical Stimulus Involved In Sensory Perception Acylglycerol Catabolic Process Diacylglycerol Catabolic Process Lipid Biosynthetic Process Amino Acid Transport Organic Anion Transport Telomerase RNA Localization To Cajal Body Sensory Perception Of Taste Response To Mechanical Stimulus Plasma Membrane	PH-gated Chloride Channel Activity Nitrate Transmembrane Transporter Activity Nitrate Transmembrane Transport Membrane Endoplasmic Reticulum C-8 Sterol Isomerase Activity Endoplasmic Reticulum Membrane Cholesterol-5,6-oxide Hydrolase Activity Cholestenol Delta-isomerase Activity Retrograde Transporter Complex, Golgi To ER D-lysine 5,6-aminomutase Activity Ether Hydrolase Activity Alkenylglycerophosphocholine Hydrolase Activity Cholesterol Biosynthetic Process Via Lathosterol Cholesterol Biosynthetic Process Via Desmosterol Cholesterol Metabolic Process Steroid Delta-isomerase Activity Extracellular Matrix Constituent Secretion Sterol Metabolic Process Transporter Complex Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Cone Photoreceptor Outer Segment Monoatomic Anion Channel Activity Renal Water Transport Ammonium Channel Activity Ossification Involved In Bone Maturation Rod Photoreceptor Outer Segment
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