POLR3F and BDP1

Number of citations of the paper that reports this interaction (PubMedID 35271311)
106

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		POLR3F	BDP1
Description		RNA polymerase III subunit F	BDP1 general transcription factor IIIB subunit
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GO Annotations	Cellular Component	DNA-directed RNA Polymerase Complex Nucleus Nucleoplasm RNA Polymerase III Complex Cytoplasm Cytosol	Transcription Factor TFIIIB Complex Nucleus Nucleoplasm
	Molecular Function	DNA Binding Double-stranded DNA Binding DNA-directed RNA Polymerase Activity Protein Binding 4 Iron, 4 Sulfur Cluster Binding	TFIIIC-class Transcription Factor Complex Binding Protein Binding
	Biological Process	Immune System Process Regulation Of Transcription By RNA Polymerase III Transcription By RNA Polymerase III Positive Regulation Of Interferon-beta Production Innate Immune Response Positive Regulation Of Innate Immune Response Defense Response To Virus	RNA Polymerase III Preinitiation Complex Assembly
Pathways		Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter	RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Obesity-related traits ( 23251661)
Interacting Genes		15 interacting genes: ATPAF2 BDP1 BRF1 ERG28 GTF3C4 KAT5 LRIF1 PRP4K RIN3 STC2 SUV39H2 TBP TNS2 UBE2G2 WDR89	4 interacting genes: CSNK2A1 POLR3F RB1 ZBTB43
Entrez ID		10621	55814
HPRD ID		15156	06114
Ensembl ID		ENSG00000132664	ENSG00000145734
Uniprot IDs		A0A8V8TL53 A0A8V8TMS0 Q05DB8 Q9H1D9	A0A0G2JNU3 A6H8Y1
PDB IDs		2DK5 2YU3 7A6H 7AE1 7AE3 7AEA 7AST 7D58 7D59 7DN3 7DU2 7FJI 7FJJ 8ITY 8IUE 8IUH 9FSO 9FSP 9FSQ 9FSR 9FSS	5N9G 8ITY 8IUE 8IUH 9FSO 9FSP 9FSQ 9FSR 9FSS
Enriched GO Terms of Interacting Partners?		RNA Polymerase III General Transcription Initiation Factor Activity Transcription By RNA Polymerase III Transcription Factor TFIIIB Complex Transcription Initiation At RNA Polymerase III Promoter Transcription Preinitiation Complex Assembly TRNA Transcription DNA-templated Transcription Initiation RRNA Transcription Protein-lysine-acetyltransferase Activity Histone Acetyltransferase Activity Chromosome, Centromeric Region Protein-DNA Complex Assembly Histone H2AK5 Acetyltransferase Activity RNA Polymerase III Preinitiation Complex Assembly Negative Regulation Of Mast Cell Chemotaxis	Regulation Of DNA-templated Transcription Regulation Of Chromosome Segregation Protein Localization To Chromosome Negative Regulation Of Apoptotic Signaling Pathway Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Positive Regulation Of Aggrephagy Negative Regulation Of Cell Cycle Phase Transition Regulation Of RNA Biosynthetic Process Regulation Of Chromosome Separation PML Body Sister Chromatid Biorientation Maintenance Of Mitotic Sister Chromatid Cohesion Regulation Of Lipid Kinase Activity Glial Cell Apoptotic Process Rb-E2F Complex Chromatin Lock Complex Positive Regulation Of Collagen Fibril Organization RNA Polymerase III General Transcription Initiation Factor Binding Regulation Of RNA Metabolic Process Negative Regulation Of Cell Cycle Process Negative Regulation Of Myofibroblast Differentiation Negative Regulation Of Hepatocyte Apoptotic Process Enucleate Erythrocyte Differentiation Regulation Of Centromere Complex Assembly RNA Metabolic Process Regulation Of Myofibroblast Differentiation Regulation Of Collagen Fibril Organization Cyclin/CDK Positive Transcription Elongation Factor Complex Importin-alpha Family Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process Double-strand Break Repair Via Classical Nonhomologous End Joining Negative Regulation Of Cell Cycle Positive Regulation Of Transcription Regulatory Region DNA Binding Regulation Of Apoptotic Signaling Pathway Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Aggrephagy Regulation Of Cell Growth Protein Targeting To Vacuole Involved In Autophagy MRNA Methylguanosine-cap Decapping Regulation Of Cell Cycle Phase Transition DNA-templated Transcription Positive Regulation Of Macrophage Differentiation Hepatocyte Apoptotic Process Negative Regulation Of Glial Cell Proliferation RNA Polymerase III Complex Positive Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Transcription Regulatory Region DNA Binding RNA Decapping Sin3-type Complex
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