POLR3F and SUV39H2

Number of citations of the paper that reports this interaction (PubMedID 23455924)
0

Data Source:
BioGRID (two hybrid)

		POLR3F	SUV39H2
Description		RNA polymerase III subunit F	SUV39H2 histone lysine methyltransferase
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GO Annotations	Cellular Component	DNA-directed RNA Polymerase Complex Nucleus Nucleoplasm RNA Polymerase III Complex Cytoplasm Cytosol	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromosome
	Molecular Function	DNA Binding Double-stranded DNA Binding DNA-directed RNA Polymerase Activity Protein Binding 4 Iron, 4 Sulfur Cluster Binding	Transcription Cis-regulatory Region Binding Protein Binding Methyltransferase Activity Zinc Ion Binding Transferase Activity Histone Methyltransferase Activity Metal Ion Binding Histone H3K9 Methyltransferase Activity Histone H3 Methyltransferase Activity Histone H3K9 Trimethyltransferase Activity S-adenosyl-L-methionine Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Immune System Process Regulation Of Transcription By RNA Polymerase III Transcription By RNA Polymerase III Positive Regulation Of Interferon-beta Production Innate Immune Response Positive Regulation Of Innate Immune Response Defense Response To Virus	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Chromatin Remodeling Circadian Rhythm Cell Differentiation Methylation Epigenetic Programming In The Zygotic Pronuclei Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of DNA-templated Transcription Rhythmic Process Cellular Response To Hypoxia
Pathways		Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter	PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		15 interacting genes: ATPAF2 BDP1 BRF1 ERG28 GTF3C4 KAT5 LRIF1 PRP4K RIN3 STC2 SUV39H2 TBP TNS2 UBE2G2 WDR89	43 interacting genes: AKAP9 APPL2 AR BLZF1 C8orf74 CBX7 CDCA4 CEP70 CFAP100 CGGBP1 EWSR1 FAM20C GOLGA6L9 GSTCD H3C1 ID2 KCTD17 KLF3 KLHDC4 LCA5L LNX1 LRIF1 MAGEA11 MCM3AP MRFAP1 MTF2 MYL12A NME4 ODAD3 PHF19 PNMA1 POLR3F RAB3IP RASSF1 SHC1 SMAD5 SNF8 UBE2V2 VHL WIZ ZNF212 ZNF557 ZNF57
Entrez ID		10621	79723
HPRD ID		15156	07580
Ensembl ID		ENSG00000132664	ENSG00000152455
Uniprot IDs		A0A8V8TL53 A0A8V8TMS0 Q05DB8 Q9H1D9	Q9H5I1
PDB IDs		2DK5 2YU3 7A6H 7AE1 7AE3 7AEA 7AST 7D58 7D59 7DN3 7DU2 7FJI 7FJJ 8ITY 8IUE 8IUH 9FSO 9FSP 9FSQ 9FSR 9FSS	2R3A 6P0R
Enriched GO Terms of Interacting Partners?		RNA Polymerase III General Transcription Initiation Factor Activity Transcription By RNA Polymerase III Transcription Factor TFIIIB Complex Transcription Initiation At RNA Polymerase III Promoter Transcription Preinitiation Complex Assembly TRNA Transcription DNA-templated Transcription Initiation RRNA Transcription Protein-lysine-acetyltransferase Activity Histone Acetyltransferase Activity Chromosome, Centromeric Region Protein-DNA Complex Assembly Histone H2AK5 Acetyltransferase Activity RNA Polymerase III Preinitiation Complex Assembly Negative Regulation Of Mast Cell Chemotaxis	Nucleoplasm Protein Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Histone H3K36me3 Reader Activity Nucleus Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
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