STIP1 and FEZ2

Number of citations of the paper that reports this interaction (PubMedID 23938469)
66

Data Source:
BioGRID (two hybrid)

		STIP1	FEZ2
Description		stress induced phosphoprotein 1	fasciculation and elongation protein zeta 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Golgi Apparatus Cytosol Protein-containing Complex Protein Folding Chaperone Complex Dynein Axonemal Particle	Cytoplasm Axon
	Molecular Function	RNA Binding Protein Binding Hsp90 Protein Binding	Protein Binding
	Biological Process	Cellular Response To Interleukin-7	Signal Transduction Nervous System Development Axon Guidance Negative Regulation Of Autophagosome Assembly
Pathways		HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand RND1 GTPase cycle
Drugs		Copper
Diseases
GWAS		A body shape index ( 34021172) Attention deficit hyperactivity disorder ( 21784300) Crohn's disease ( 28067908) Fruit consumption ( 32066663) Monocyte count ( 32888494) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Apolipoprotein A1 levels ( 32203549) Haemorrhoidal disease ( 33888516) Hip circumference adjusted for BMI ( 34021172) Intraocular pressure ( 29617998) Metabolite levels ( 23823483) Offspring birth weight ( 31043758) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		35 interacting genes: ACD ACVR1 AIP APP CBX4 CDC37 CHD3 CLCN1 CLK1 EGFR ERBB2 FEZ2 FKBP5 HIPK2 HSP90AA1 HSPA14 HSPA1A HSPA4 HSPA8 LAMB2 LMO2 MAGED4 MAP3K8 OGT PIAS2 PIAS3 PIAS4 POT1 PRNP PTGES3 RASGRF1 SUMO2 SUMO4 UBE2I UBR5	18 interacting genes: BRD1 CLASP2 DRAP1 FEZ1 KPNA2 NEK1 PDCD7 PRKCZ RAB3GAP1 RAI14 SAP30L SMC3 STIP1 TBC1D25 TEDC2 TLK2 WWC1 ZNF251
Entrez ID		10963	9637
HPRD ID		05454	09213
Ensembl ID		ENSG00000168439	ENSG00000171055
Uniprot IDs		P31948 V9HW72	Q9UHY8
PDB IDs		1ELR 1ELW 2LNI 2NC9 3ESK 3FWV 7KW7
Enriched GO Terms of Interacting Partners?		SUMO Transferase Activity Protein Sumoylation Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Biosynthetic Process Protein Folding ATP-dependent Protein Folding Chaperone SUMO Ligase Activity Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of DNA-templated Transcription PML Body Chaperone-mediated Protein Complex Assembly Unfolded Protein Binding Telomere Maintenance Via Telomerase Negative Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process RNA-templated DNA Biosynthetic Process Heat Shock Protein Binding Protein Refolding Negative Regulation Of RNA Metabolic Process Telomere Maintenance Via Telomere Lengthening Regulation Of DNA-templated Transcription Protein Folding Chaperone Complex Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Protein Localization Regulation Of Signal Transduction Regulation Of Telomere Maintenance Via Telomerase Protein-folding Chaperone Binding ATP Binding Regulation Of RNA Metabolic Process Negative Regulation Of Metabolic Process Negative Regulation Of Signal Transduction Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Biosynthetic Process Ubiquitin Protein Ligase Binding Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Intracellular Signal Transduction Negative Regulation Of Cell Communication Negative Regulation Of Signaling Protein Folding Chaperone Positive Regulation Of Signal Transduction Positive Regulation Of Metabolic Process Positive Regulation Of Intracellular Signal Transduction Regulation Of Transcription By RNA Polymerase II Regulation Of Signaling	Establishment Or Maintenance Of Cell Polarity Establishment Of Cell Polarity
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