STIP1 and PTGES3

Number of citations of the paper that reports this interaction (PMID 11809754)
32

Data Source:
HPRD (in vitro)

		STIP1	PTGES3
Gene Name		stress-induced phosphoprotein 1	prostaglandin E synthase 3 (cytosolic)
Image
Gene Ontology Annotations	Cellular Component	Nucleus Golgi Apparatus	Chromosome, Telomeric Region Nucleus Nucleoplasm Telomerase Holoenzyme Complex Cytoplasm Cytosol Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Poly(A) RNA Binding	Telomerase Activity Protein Binding Prostaglandin-E Synthase Activity Unfolded Protein Binding
	Biological Process	Response To Stress	Telomere Maintenance Prostaglandin Biosynthetic Process RNA-dependent DNA Replication Signal Transduction Arachidonic Acid Metabolic Process Cyclooxygenase Pathway Cellular Response To Heat Small Molecule Metabolic Process Chaperone Cofactor-dependent Protein Refolding Regulation Of Cellular Response To Heat
Pathways			Arachidonic acid metabolism HSF1 activation HSF1-dependent transactivation Metabolism of lipids and lipoproteins Attenuation phase Cellular response to heat stress Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 21784300)	Mean platelet volume ( 22139419) Platelet counts ( 22139419)
Protein-Protein Interactions		18 interactors: ACD AIP APP CDC37 EGFR FKBP4 FKBP5 HSP90AA1 HSPA14 HSPA1A HSPA4 HSPA8 LMO2 MAP3K8 POT1 PRNP PTGES3 SUMO4	25 interactors: AHR AIP ARNT CASP3 CASP7 CAV3 CD2AP COPG1 COPG2 DNAJB1 DNMT3A EIF2AK2 ERBB3 ESR1 FES GZMB HSF1 HSP90AA1 HSPA1A NR3C1 NR3C2 STIP1 SURF1 TERT THRA
Entrez ID		10963	10728
HPRD ID		05454	06138
Ensembl ID		ENSG00000168439	ENSG00000110958
Uniprot IDs		P31948	Q15185
PDB IDs		1ELR 1ELW 2LNI 3ESK 3FWV	1EJF 1LG0
Enriched GO Terms of Interacting Partners?		Protein Folding Regulation Of Cellular Response To Heat Protein Refolding Cellular Response To Heat Response To Heat Chaperone-mediated Protein Folding Response To Temperature Stimulus Cellular Protein Metabolic Process Response To Unfolded Protein Protein Import Into Mitochondrial Outer Membrane Telomere Assembly Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Capping Axon Guidance Response To Abiotic Stimulus Positive Regulation Of Telomerase Activity Protein Metabolic Process Protein Targeting To Mitochondrion Positive Regulation Of DNA Replication Telomere Maintenance Protein Localization To Mitochondrion Negative Regulation Of Telomere Maintenance Regulation Of Immune System Process Regulation Of Telomere Maintenance Via Telomerase Axonogenesis Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Chaperone-mediated Protein Complex Assembly Axon Development Response To Stress Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Telomerase Activity Chemotaxis Cellular Metabolic Process Intracellular Transport Neuron Projection Morphogenesis Cellular Copper Ion Homeostasis Regulation Of Telomere Maintenance Positive Regulation Of DNA Biosynthetic Process Regulation Of DNA Replication RNA-dependent DNA Replication Copper Ion Homeostasis Cell Morphogenesis Involved In Differentiation Regulation Of Catalytic Activity Positive Regulation Of DNA Metabolic Process Cellular Localization Mitochondrial Transport Locomotion Response To Oxidative Stress Protein Targeting	Regulation Of Cellular Response To Heat Response To Stimulus Cellular Response To Stimulus Positive Regulation Of Metabolic Process Response To Organic Substance Positive Regulation Of Cellular Metabolic Process Cellular Response To Heat Regulation Of Apoptotic Process Regulation Of Cell Proliferation Protein Refolding Response To Temperature Stimulus Regulation Of Cellular Component Organization Regulation Of Cell Death Intracellular Receptor Signaling Pathway Steroid Hormone Mediated Signaling Pathway Response To Heat Regulation Of Nitric-oxide Synthase Activity Response To Unfolded Protein Hormone-mediated Signaling Pathway Regulation Of Protein Complex Assembly Transcription From RNA Polymerase II Promoter Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Steroid Hormone Stimulus Regulation Of Metabolic Process Regulation Of Immune System Process Signal Transduction Regulation Of Signal Transduction Cellular Response To Organic Cyclic Compound Negative Regulation Of Inclusion Body Assembly Response To Stress Gene Expression Cellular Response To Organic Substance Positive Regulation Of Myeloid Cell Differentiation Regulation Of Oxidoreductase Activity Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C DNA-templated Transcription, Initiation Response To Abiotic Stimulus Positive Regulation Of Microtubule Polymerization Signaling Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Signaling Cell Communication Organelle Organization Negative Regulation Of Cellular Metabolic Process Regulation Of Inclusion Body Assembly Positive Regulation Of Protein Metabolic Process Protein Folding Nucleobase-containing Compound Metabolic Process
Tagcloud ?		amongst chaperones chaperoning depleted dnaja1 dnajb1 dnajb6 dnajb8 dnhsf1 glucocorticoid hsf1 hsp90 hsp90aa1 hspa1a hspa6 hspb1 hspb8 limiting machines maintains p23 proteostasis proteotoxic ptges3 rescued severely st13 stressed transcriptomes	12q13 15q25 15q26 3p22 50k beadchip centric cornell customized decile ecg heritability humancvd illumina lvh lyon nmb prognostically qrs rs2290893 rs2292462 rs4966014 rs6797133 scn5a sokolow sum trait typed voltage
Tagcloud (Difference) ?		amongst chaperones chaperoning depleted dnaja1 dnajb1 dnajb6 dnajb8 dnhsf1 glucocorticoid hsf1 hsp90 hsp90aa1 hspa1a hspa6 hspb1 hspb8 limiting machines maintains p23 proteostasis proteotoxic rescued severely st13 stressed transcriptomes	12q13 15q25 15q26 3p22 50k beadchip centric cornell customized decile ecg heritability humancvd illumina lvh lyon nmb prognostically qrs rs2290893 rs2292462 rs4966014 rs6797133 scn5a sokolow sum trait typed voltage
Tagcloud (Intersection) ?		ptges3