STIP1 and HSPA14

Number of citations of the paper that reports this interaction (PMID 10786835)
258

Data Source:
HPRD (in vitro)

		STIP1	HSPA14
Gene Name		stress-induced phosphoprotein 1	heat shock 70kDa protein 14
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Golgi Apparatus	Cytosol Ribosome Membrane
	Molecular Function	Protein Binding Poly(A) RNA Binding	Protein Binding ATP Binding
	Biological Process	Response To Stress	'de Novo' Cotranslational Protein Folding
Pathways
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 21784300)
Protein-Protein Interactions		18 interactors: ACD AIP APP CDC37 EGFR FKBP4 FKBP5 HSP90AA1 HSPA14 HSPA1A HSPA4 HSPA8 LMO2 MAP3K8 POT1 PRNP PTGES3 SUMO4	5 interactors: BARD1 BRCA1 DNAJC2 PAXIP1 STIP1
Entrez ID		10963	51182
HPRD ID		05454	07021
Ensembl ID		ENSG00000168439	ENSG00000187522
Uniprot IDs		P31948	B0YIZ1 Q0VDF9 Q8TAQ0
PDB IDs		1ELR 1ELW 2LNI 3ESK 3FWV
Enriched GO Terms of Interacting Partners?		Protein Folding Regulation Of Cellular Response To Heat Protein Refolding Cellular Response To Heat Response To Heat Chaperone-mediated Protein Folding Response To Temperature Stimulus Cellular Protein Metabolic Process Response To Unfolded Protein Protein Import Into Mitochondrial Outer Membrane Telomere Assembly Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Capping Axon Guidance Response To Abiotic Stimulus Positive Regulation Of Telomerase Activity Protein Metabolic Process Protein Targeting To Mitochondrion Positive Regulation Of DNA Replication Telomere Maintenance Protein Localization To Mitochondrion Negative Regulation Of Telomere Maintenance Regulation Of Immune System Process Regulation Of Telomere Maintenance Via Telomerase Axonogenesis Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Chaperone-mediated Protein Complex Assembly Axon Development Response To Stress Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Telomerase Activity Chemotaxis Cellular Metabolic Process Intracellular Transport Neuron Projection Morphogenesis Cellular Copper Ion Homeostasis Regulation Of Telomere Maintenance Positive Regulation Of DNA Biosynthetic Process Regulation Of DNA Replication RNA-dependent DNA Replication Copper Ion Homeostasis Cell Morphogenesis Involved In Differentiation Regulation Of Catalytic Activity Positive Regulation Of DNA Metabolic Process Cellular Localization Mitochondrial Transport Locomotion Response To Oxidative Stress Protein Targeting	Protein K6-linked Ubiquitination Positive Regulation Of Histone H3-K4 Methylation Positive Regulation Of Histone Acetylation Regulation Of Histone H3-K4 Methylation Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Protein Acetylation DNA Metabolic Process Positive Regulation Of Histone Methylation Regulation Of Histone Acetylation Regulation Of Histone Methylation Positive Regulation Of Histone Modification DNA Damage Response, Signal Transduction By P53 Class Mediator DNA Repair Signal Transduction In Response To DNA Damage Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H3-K36 Methylation Positive Regulation Of Histone H4-K16 Acetylation Signal Transduction By P53 Class Mediator Regulation Of Histone Modification Positive Regulation Of Protein Ubiquitination Response To Ionizing Radiation Positive Regulation Of DNA Metabolic Process Negative Regulation Of MRNA 3'-end Processing 'de Novo' Cotranslational Protein Folding Positive Regulation Of Histone H3-K9 Acetylation Cellular Response To DNA Damage Stimulus Protein Polyubiquitination Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Regulation Of Chromosome Organization Regulation Of Protein Ubiquitination DNA Recombination Cellular Response To Indole-3-methanol Negative Regulation Of Centriole Replication Positive Regulation Of Protein Metabolic Process DNA Replication Negative Regulation Of Protein Export From Nucleus Dosage Compensation By Inactivation Of X Chromosome Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Histone H3-K9 Methylation Dosage Compensation Chorion Development Regulation Of Histone H3-K9 Acetylation Positive Regulation Of Metabolic Process Response To Stress Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Stress Regulation Of Centriole Replication Positive Regulation Of Gene Expression
Tagcloud ?		amongst chaperones chaperoning depleted dnaja1 dnajb1 dnajb6 dnajb8 dnhsf1 glucocorticoid hsf1 hsp90 hsp90aa1 hspa1a hspa6 hspb1 hspb8 limiting machines maintains p23 proteostasis proteotoxic ptges3 rescued severely st13 stressed transcriptomes	apg1 forelimb forelimbs grp94 hindlimb hindlimbs hsp10 hsp105 hsp110 hsp20 hsp22 hsp25 hsp47 hsp60 hspb10 hspb2 hspb3 hspb4 hspb7 hspb9 hsps oligodactylic performs phocomelic trap1
Tagcloud (Difference) ?		amongst chaperones chaperoning depleted dnaja1 dnajb1 dnajb6 dnajb8 dnhsf1 glucocorticoid hsf1 hsp90 hsp90aa1 hspa1a hspa6 hspb1 hspb8 limiting machines maintains p23 proteostasis proteotoxic ptges3 rescued severely st13 stressed transcriptomes	apg1 forelimb forelimbs grp94 hindlimb hindlimbs hsp10 hsp105 hsp110 hsp20 hsp22 hsp25 hsp47 hsp60 hspb10 hspb2 hspb3 hspb4 hspb7 hspb9 hsps oligodactylic performs phocomelic trap1
Tagcloud (Intersection) ?