Wiki-Pi
About
Search
People
Updates
Search
STIP1 and RASGRF1
Number of citations of the paper that reports this interaction (PubMedID
23938469
)
66
Data Source:
BioGRID
(two hybrid)
STIP1
RASGRF1
Description
stress induced phosphoprotein 1
Ras protein specific guanine nucleotide releasing factor 1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Golgi Apparatus
Cytosol
Protein-containing Complex
Protein Folding Chaperone Complex
Dynein Axonemal Particle
Cytosol
Plasma Membrane
Growth Cone
Neuron Projection
Molecular Function
RNA Binding
Protein Binding
Hsp90 Protein Binding
Guanyl-nucleotide Exchange Factor Activity
Glutamate Receptor Binding
Biological Process
Cellular Response To Interleukin-7
Signal Transduction
Small GTPase-mediated Signal Transduction
Ras Protein Signal Transduction
Long-term Memory
Neuron Projection Development
Response To Endoplasmic Reticulum Stress
Positive Regulation Of Rac Protein Signal Transduction
Intracellular Signal Transduction
Negative Regulation Of MAPK Cascade
Positive Regulation Of MAPK Cascade
Type B Pancreatic Cell Proliferation
Regulation Of Ras Protein Signal Transduction
Positive Regulation Of Ras Protein Signal Transduction
Regulation Of Synaptic Plasticity
Regulation Of Neuronal Synaptic Plasticity
Pathways
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
RND1 GTPase cycle
Ras activation upon Ca2+ influx through NMDA receptor
RAF/MAP kinase cascade
Drugs
Copper
Diseases
GWAS
A body shape index (
34021172
)
Attention deficit hyperactivity disorder (
21784300
)
Crohn's disease (
28067908
)
Fruit consumption (
32066663
)
Monocyte count (
32888494
)
Waist circumference adjusted for body mass index (
34021172
)
Waist-hip index (
34021172
)
Waist-to-hip ratio adjusted for BMI (
34021172
)
Adult body size (
32376654
)
Bronchopulmonary dysplasia (
23897914
)
Hand grip strength (
29691431
)
High myopia (
32428537
)
Myopia (
27182965
)
Pancreatic beta-cell glucose sensitivity (
32944759
)
Refractive error (
20835236
23396134
32231278
)
RR interval (heart rate) (
20031603
)
Spherical equivalent (joint analysis main effects and education interaction) (
27020472
)
Spherical equivalent or myopia (age of diagnosis) (
29808027
)
Interacting Genes
35 interacting genes:
ACD
ACVR1
AIP
APP
CBX4
CDC37
CHD3
CLCN1
CLK1
EGFR
ERBB2
FEZ2
FKBP5
HIPK2
HSP90AA1
HSPA14
HSPA1A
HSPA4
HSPA8
LAMB2
LMO2
MAGED4
MAP3K8
OGT
PIAS2
PIAS3
PIAS4
POT1
PRNP
PTGES3
RASGRF1
SUMO2
SUMO4
UBE2I
UBR5
20 interacting genes:
CEBPA
EHD4
GRIN2B
GRK2
HRAS
NTRK1
NTRK2
NTRK3
PRKACA
RAC1
RHOA
RRAS2
SNRNP70
SRC
SRPK2
STIP1
TNK2
USP8
YWHAB
YWHAE
Entrez ID
10963
5923
HPRD ID
05454
07362
Ensembl ID
ENSG00000168439
ENSG00000058335
Uniprot IDs
P31948
V9HW72
A8K270
Q13972
Q8IUU5
PDB IDs
1ELR
1ELW
2LNI
2NC9
3ESK
3FWV
7KW7
Enriched GO Terms of Interacting Partners
?
SUMO Transferase Activity
Protein Sumoylation
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Macromolecule Biosynthetic Process
Protein Folding
ATP-dependent Protein Folding Chaperone
SUMO Ligase Activity
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Primary Metabolic Process
Regulation Of Macromolecule Metabolic Process
Negative Regulation Of DNA-templated Transcription
PML Body
Chaperone-mediated Protein Complex Assembly
Unfolded Protein Binding
Telomere Maintenance Via Telomerase
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Metabolic Process
RNA-templated DNA Biosynthetic Process
Heat Shock Protein Binding
Protein Refolding
Negative Regulation Of RNA Metabolic Process
Telomere Maintenance Via Telomere Lengthening
Regulation Of DNA-templated Transcription
Protein Folding Chaperone Complex
Regulation Of RNA Biosynthetic Process
Regulation Of Gene Expression
Regulation Of Protein Localization
Regulation Of Signal Transduction
Regulation Of Telomere Maintenance Via Telomerase
Protein-folding Chaperone Binding
ATP Binding
Regulation Of RNA Metabolic Process
Negative Regulation Of Metabolic Process
Negative Regulation Of Signal Transduction
Negative Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Macromolecule Biosynthetic Process
Ubiquitin Protein Ligase Binding
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Biosynthetic Process
Regulation Of Telomere Maintenance Via Telomere Lengthening
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Intracellular Signal Transduction
Negative Regulation Of Cell Communication
Negative Regulation Of Signaling
Protein Folding Chaperone
Positive Regulation Of Signal Transduction
Positive Regulation Of Metabolic Process
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Transcription By RNA Polymerase II
Regulation Of Signaling
Intracellular Signaling Cassette
Nucleotide Binding
Neurotrophin Receptor Activity
Neurotrophin Binding
Regulation Of Cell Junction Assembly
Cellular Response To Growth Factor Stimulus
Signal Transduction
Protein Kinase Activity
Response To Growth Factor
Intracellular Signal Transduction
Cellular Response To Nerve Growth Factor Stimulus
Response To Nerve Growth Factor
Kinase Activity
Cell Surface Receptor Signaling Pathway
Protein Tyrosine Kinase Activity
Positive Regulation Of Signal Transduction
Regulation Of Plasma Membrane Bounded Cell Projection Organization
Regulation Of Cell Projection Organization
Small GTPase-mediated Signal Transduction
Neuron Migration
Regulation Of Synapse Organization
Modulation Of Chemical Synaptic Transmission
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Positive Regulation Of Cellular Component Biogenesis
Positive Regulation Of Cellular Component Organization
Positive Regulation Of Intracellular Signal Transduction
Positive Regulation Of Cell Projection Organization
Regulation Of Cellular Component Organization
Regulation Of Signal Transduction
Phosphorylation
Mechanoreceptor Differentiation
Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Cell Migration
Neurotrophin Signaling Pathway
Protein Domain Specific Binding
Focal Adhesion
Positive Regulation Of Cell Junction Assembly
Plasma Membrane
Regulation Of Blood Circulation
Regulation Of Neuron Apoptotic Process
Perinuclear Region Of Cytoplasm
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
ATP Binding
Phosphoprotein Binding
Cell Motility
Endosome
Regulation Of Signaling
Positive Regulation Of Metabolic Process
Regulation Of Cell Communication
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?