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NCKAP1 and ABI1
Number of citations of the paper that reports this interaction (PubMedID
16055720
)
76
Data Source:
HPRD
(in vitro, two hybrid)
NCKAP1
ABI1
Description
NCK associated protein 1
abl interactor 1
Image
GO Annotations
Cellular Component
Ruffle
Cytosol
Plasma Membrane
Focal Adhesion
Membrane
Lamellipodium
SCAR Complex
Lamellipodium Membrane
Filamentous Actin
Cell Projection
Extracellular Exosome
Postsynapse
Nucleus
Cytoplasm
Endoplasmic Reticulum
Cytosol
Cytoskeleton
Postsynaptic Density
Lamellipodium
Filopodium
Growth Cone
SCAR Complex
Cell Leading Edge
Filopodium Tip
Cell Projection
Neuron Projection
Synapse
Extracellular Exosome
Actin-based Cell Projection
Molecular Function
Protein Binding
Small GTPase Binding
Protein Binding
Cytoskeletal Protein Binding
SH3 Domain Binding
Protein Tyrosine Kinase Activator Activity
Signaling Adaptor Activity
Cadherin Binding
Biological Process
Cell Morphogenesis
In Utero Embryonic Development
Somitogenesis
Neural Tube Closure
Apoptotic Process
Zygotic Determination Of Anterior/posterior Axis, Embryo
Central Nervous System Development
Endoderm Development
Mesodermal Cell Migration
Embryonic Body Morphogenesis
Positive Regulation Of Lamellipodium Assembly
Cell Migration
Rac Protein Signal Transduction
Cell Projection Assembly
Lamellipodium Assembly
Positive Regulation Of Actin Filament Polymerization
Cortical Actin Cytoskeleton Organization
Notochord Development
Establishment Or Maintenance Of Actin Cytoskeleton Polarity
Regulation Of Protein Localization
Embryonic Heart Tube Development
Cell Migration Involved In Gastrulation
Basal Protein Localization
Apical Protein Localization
Paraxial Mesoderm Development
Paraxial Mesoderm Morphogenesis
Notochord Morphogenesis
Embryonic Foregut Morphogenesis
Neuron Projection Morphogenesis
Protein Stabilization
Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Somitogenesis
Neuron Migration
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Actin Polymerization Or Depolymerization
Negative Regulation Of Cell Population Proliferation
Megakaryocyte Development
Dendrite Morphogenesis
Cell Projection Morphogenesis
Positive Regulation Of Protein Tyrosine Kinase Activity
Lamellipodium Morphogenesis
Pathways
Regulation of actin dynamics for phagocytic cup formation
Regulation of actin dynamics for phagocytic cup formation
VEGFA-VEGFR2 Pathway
RHO GTPases Activate WASPs and WAVEs
RHO GTPases Activate WASPs and WAVEs
RAC1 GTPase cycle
RAC2 GTPase cycle
RAC3 GTPase cycle
FCGR3A-mediated phagocytosis
FCGR3A-mediated phagocytosis
Regulation of actin dynamics for phagocytic cup formation
Regulation of actin dynamics for phagocytic cup formation
VEGFA-VEGFR2 Pathway
RHO GTPases Activate WASPs and WAVEs
RHO GTPases Activate WASPs and WAVEs
RAC1 GTPase cycle
RAC2 GTPase cycle
RAC3 GTPase cycle
FCGR3A-mediated phagocytosis
FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS
Neurological blood protein biomarker levels (
31320639
)
Interacting Genes
16 interacting genes:
ABI1
BRK1
CYFIP2
DNMBP
GAS7
MYO16
NCK1
NYAP1
NYAP2
RAC1
SPP1
TMEM132D
WASF1
WASF2
WEE2-AS1
YWHAG
67 interacting genes:
ABL1
AKT1
APBB1
C22orf15
CACNA1A
CCDC57
CCHCR1
CYFIP2
DST
DTNB
EIF3H
ENAH
ENKD1
EPS8
EPS8L1
EVL
FAM124B
FBXL19
FHL2
FXR1
GAS7
HHEX
HNRNPK
HOMER1
HOMER3
HSPA8
KIAA0408
KIAA1217
KTN1
LMO1
MAB21L2
MINK1
MRFAP1
MRFAP1L1
NCK1
NCK2
NCKAP1
NEB
NFASC
NIN
OGT
PAK2
PCM1
PRKAA2
PRPF40A
RBM15
RCOR3
SHANK3
SMARCD1
SORBS1
SORBS2
SOS1
SOS2
SPTA1
SPTAN1
SRP68
SRRM1
SYNE2
TCERG1
TLN1
TRIP10
TSC1
TTC23
VARS2
VASP
WASF1
WASF2
Entrez ID
10787
10006
HPRD ID
05353
04336
Ensembl ID
ENSG00000061676
ENSG00000136754
Uniprot IDs
A0A994J4I5
A0A994J6K9
Q9Y2A7
A0A0A0MRT6
B6VEX3
B6VEX4
B6VEX5
Q8IZP0
PDB IDs
3P8C
4N78
7USC
7USD
7USE
7LXE
Enriched GO Terms of Interacting Partners
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SCAR Complex
Cell Projection Morphogenesis
Cell Projection Organization
Lamellipodium Organization
Rac Protein Signal Transduction
Lamellipodium Morphogenesis
Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Regulation Of Actin Filament Organization
Neuron Projection Morphogenesis
Positive Regulation Of Actin Nucleation
Positive Regulation Of Supramolecular Fiber Organization
Regulation Of Actin Cytoskeleton Organization
Positive Regulation Of Cytoskeleton Organization
Lamellipodium
Regulation Of Actin Filament-based Process
Regulation Of Supramolecular Fiber Organization
Anatomical Structure Morphogenesis
Positive Regulation Of Lamellipodium Assembly
Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Actin Filament Organization
Positive Regulation Of Lamellipodium Organization
Regulation Of Actin Nucleation
Lamellipodium Assembly
Regulation Of Cytoskeleton Organization
Regulation Of Lamellipodium Assembly
Intracellular Signaling Cassette
Plasma Membrane Bounded Cell Projection Organization
Regulation Of Actin Polymerization Or Depolymerization
Regulation Of Actin Filament Length
Intracellular Signal Transduction
Positive Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Synapse
Regulation Of Lamellipodium Organization
Cell Projection Assembly
Actin Polymerization Or Depolymerization
Signal Transduction
Dendrite Extension
Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Supramolecular Fiber Organization
Regulation Of Cellular Component Size
Positive Regulation Of Organelle Organization
Arp2/3 Complex Binding
Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Small GTPase-mediated Signal Transduction
Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly
Regulation Of Actin Filament Polymerization
Megakaryocyte Development
Regulation Of Plasma Membrane Bounded Cell Projection Organization
Protein Kinase A Regulatory Subunit Binding
Protein Kinase A Binding
Regulation Of Actin Filament Organization
Regulation Of Actin Cytoskeleton Organization
Regulation Of Supramolecular Fiber Organization
Regulation Of Actin Filament-based Process
Focal Adhesion
Regulation Of Cytoskeleton Organization
Actin Binding
Cell Projection
Regulation Of Actin Filament Length
Regulation Of Cellular Component Size
Cell Projection Organization
Cytoskeleton Organization
Regulation Of Actin Filament Polymerization
Lamellipodium
Postsynaptic Density
Regulation Of Actin Polymerization Or Depolymerization
Actin Filament Organization
Actin Filament-based Process
Actin Cytoskeleton Organization
Regulation Of Organelle Organization
Cytoplasm
Supramolecular Fiber Organization
SCAR Complex
Protein Binding
Regulation Of Protein-containing Complex Assembly
Plasma Membrane Bounded Cell Projection Organization
Regulation Of Translational Initiation
Regulation Of Plasma Membrane Bounded Cell Projection Organization
Regulation Of Cellular Component Organization
Postsynapse
Regulation Of Cell Projection Organization
Positive Regulation Of Supramolecular Fiber Organization
Cadherin Binding
Synapse
Positive Regulation Of Cytoskeleton Organization
Lamellipodium Organization
Positive Regulation Of Actin Filament Polymerization
Organelle Organization
Cytoskeleton
Cytosol
Rac Protein Signal Transduction
Negative Regulation Of Supramolecular Fiber Organization
Actin Polymerization Or Depolymerization
Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Anchoring Junction
Positive Regulation Of Cellular Component Biogenesis
SH3 Domain Binding
Positive Regulation Of Cellular Component Organization
Cell Cortex
Profilin Binding
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Tagcloud (Difference)
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Tagcloud (Intersection)
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