PTK6 and KHDRBS2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PTK6	KHDRBS2
Gene Name		protein tyrosine kinase 6	KH domain containing, RNA binding, signal transduction associated 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Ruffle Nucleus Nucleoplasm Cytoplasm Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane	Nucleus
	Molecular Function	Non-membrane Spanning Protein Tyrosine Kinase Activity Receptor Binding Protein Binding ATP Binding Identical Protein Binding	Protein Binding Poly(A) Binding Poly(U) RNA Binding SH3 Domain Binding SH2 Domain Binding Protein Heterodimerization Activity
	Biological Process	Protein Phosphorylation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Neuron Projection Development Cell Migration Actin Cytoskeleton Organization Peptidyl-tyrosine Autophosphorylation Regulation Of Cell Proliferation Tyrosine Phosphorylation Of Stat3 Protein Tyrosine Phosphorylation Of Stat5 Protein Innate Immune Response Negative Regulation Of Growth Protein Autophosphorylation Intestinal Epithelial Cell Differentiation Negative Regulation Of Protein Tyrosine Kinase Activity Cellular Response To Retinoic Acid	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)	Protein quantitative trait loci ( 18464913)
Protein-Protein Interactions		14 interactors: APP CCDC33 DOK1 EFHC2 EGFR ERBB3 EXOC5 FCHO1 FGFR1 KHDRBS1 KHDRBS2 REL STAP2 WASL	29 interactors: AEN CATSPER1 CHTOP CIRBP DOCK2 EWSR1 GRB2 HBZ HNRNPK HNRNPR KHDRBS3 LINC01018 MTA1 NABP1 NCOA5 NPDC1 PRMT1 PRPF31 PRR3 PTK6 RBM3 RBMX SDCBP SPG7 SULT1A3 TYK2 TYMSOS YTHDC1 ZFC3H1
Entrez ID		5753	202559
HPRD ID		03594	13775
Ensembl ID		ENSG00000101213	ENSG00000112232
Uniprot IDs		Q13882	Q5VWX1
PDB IDs		1RJA 2KGT
Enriched GO Terms of Interacting Partners?		Innate Immune Response Fc Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Protein Metabolic Process Immune Response Defense Response Immune Response-regulating Cell Surface Receptor Signaling Pathway Axon Guidance Enzyme Linked Receptor Protein Signaling Pathway Phosphatidylinositol-mediated Signaling Immune Response-regulating Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Axonogenesis Response To Fibroblast Growth Factor Positive Regulation Of Cellular Protein Metabolic Process Axon Development Regulation Of Peptidyl-tyrosine Phosphorylation Cell Morphogenesis Involved In Neuron Differentiation Neurotrophin TRK Receptor Signaling Pathway Chemotaxis Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Signal Transduction Neuron Projection Morphogenesis Immune System Process Salivary Gland Morphogenesis Regulation Of Protein Metabolic Process Salivary Gland Development Cell Morphogenesis Involved In Differentiation Peptidyl-tyrosine Phosphorylation Regulation Of Protein Kinase Activity Positive Regulation Of Cell Cycle Gene Expression Exocrine System Development Positive Regulation Of Phospholipase C Activity Regulation Of Nitrogen Compound Metabolic Process Neuron Apoptotic Process Regulation Of Kinase Activity Cellular Macromolecule Biosynthetic Process Positive Regulation Of Intracellular Signal Transduction Regulation Of Protein Tyrosine Kinase Activity Neuron Projection Development Macromolecule Biosynthetic Process Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Neuron Death	RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleobase-containing Compound Metabolic Process Response To Ionizing Radiation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Splicing Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process MRNA Processing Gene Expression Response To Radiation Nitrogen Compound Metabolic Process MRNA Metabolic Process Cellular Process Ribonucleoprotein Complex Assembly Peptidyl-tyrosine Autophosphorylation Response To Abiotic Stimulus Regulation Of Metabolic Process Cellular Metabolic Process Response To Cold Locomotion Positive Regulation Of Metabolic Process Myeloid Dendritic Cell Activation Involved In Immune Response Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Protein Autoubiquitination Cell Motility Cell-cell Recognition Cellular Component Assembly Positive Regulation Of Translation Regulation Of Protein Autoubiquitination Membrane Raft Polarization Movement Of Cell Or Subcellular Component Regulation Of Cellular Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Extracellular Vesicular Exosome Assembly Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Alpha-beta T Cell Proliferation Tyrosine Phosphorylation Of Stat5 Protein Ribonucleoprotein Complex Biogenesis
Tagcloud ?		1r additive additively attractive benefit cancers co combined depends depleted develops dimensional directed exist her2 her3 interestingly partners powerful promoting reveals rnai simultaneously stronger successfully tumour tumourigenesis tumours xenografts
Tagcloud (Difference) ?		1r additive additively attractive benefit cancers co combined depends depleted develops dimensional directed exist her2 her3 interestingly partners powerful promoting reveals rnai simultaneously stronger successfully tumour tumourigenesis tumours xenografts
Tagcloud (Intersection) ?