PTK6 and CCDC33

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PTK6	CCDC33
Gene Name		protein tyrosine kinase 6	coiled-coil domain containing 33
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Ruffle Nucleus Nucleoplasm Cytoplasm Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
	Molecular Function	Non-membrane Spanning Protein Tyrosine Kinase Activity Receptor Binding Protein Binding ATP Binding Identical Protein Binding	Protein Binding
	Biological Process	Protein Phosphorylation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Neuron Projection Development Cell Migration Actin Cytoskeleton Organization Peptidyl-tyrosine Autophosphorylation Regulation Of Cell Proliferation Tyrosine Phosphorylation Of Stat3 Protein Tyrosine Phosphorylation Of Stat5 Protein Innate Immune Response Negative Regulation Of Growth Protein Autophosphorylation Intestinal Epithelial Cell Differentiation Negative Regulation Of Protein Tyrosine Kinase Activity Cellular Response To Retinoic Acid
Pathways
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)	Obesity-related traits ( 23251661)
Protein-Protein Interactions		14 interactors: APP CCDC33 DOK1 EFHC2 EGFR ERBB3 EXOC5 FCHO1 FGFR1 KHDRBS1 KHDRBS2 REL STAP2 WASL	91 interactors: ABCF3 ABLIM3 APP ARIH2 ARMC7 ARNT2 BCCIP BLK BLZF1 BYSL CALCOCO2 CCDC102B CCDC85B CCNH CDCA7L CDKN2B CENPP CHCHD3 DGCR6 DIP2A DVL2 EFEMP2 EHMT2 EMC2 EMD FAM124A FAM161A FXR2 GPATCH2L GRN HGS HNRNPF HNRNPK HOOK2 HOXA1 ING5 KANK2 KCTD19 KCTD9 KHDRBS3 KIFC3 KXD1 LDOC1 LMO2 LMO3 MAGED1 MAPK9 MDFI MIPOL1 MOS NAB2 NCK2 NDOR1 NECAB2 NINL OSGIN1 PID1 PIN1 PLSCR1 PNMA1 PNMA2 POLR1C PPP2R3C PRKAB2 PTGER3 PTK6 RAD54B RBMX RHOXF2 SCNM1 SMAD3 SPAG5 SPG21 SSSCA1 STK16 STX11 TGFB1 TMCC2 TRAF2 TRIM37 TRIM42 TSC22D4 TSGA10 TTC19 TUFT1 UBQLN4 USHBP1 VPS52 ZBTB8A ZGPAT ZNF572
Entrez ID		5753	80125
HPRD ID		03594	09959
Ensembl ID		ENSG00000101213	ENSG00000140481
Uniprot IDs		Q13882	Q8N5R6
PDB IDs		1RJA 2KGT
Enriched GO Terms of Interacting Partners?		Innate Immune Response Fc Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Protein Metabolic Process Immune Response Defense Response Immune Response-regulating Cell Surface Receptor Signaling Pathway Axon Guidance Enzyme Linked Receptor Protein Signaling Pathway Phosphatidylinositol-mediated Signaling Immune Response-regulating Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Axonogenesis Response To Fibroblast Growth Factor Positive Regulation Of Cellular Protein Metabolic Process Axon Development Regulation Of Peptidyl-tyrosine Phosphorylation Cell Morphogenesis Involved In Neuron Differentiation Neurotrophin TRK Receptor Signaling Pathway Chemotaxis Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Signal Transduction Neuron Projection Morphogenesis Immune System Process Salivary Gland Morphogenesis Regulation Of Protein Metabolic Process Salivary Gland Development Cell Morphogenesis Involved In Differentiation Peptidyl-tyrosine Phosphorylation Regulation Of Protein Kinase Activity Positive Regulation Of Cell Cycle Gene Expression Exocrine System Development Positive Regulation Of Phospholipase C Activity Regulation Of Nitrogen Compound Metabolic Process Neuron Apoptotic Process Regulation Of Kinase Activity Cellular Macromolecule Biosynthetic Process Positive Regulation Of Intracellular Signal Transduction Regulation Of Protein Tyrosine Kinase Activity Neuron Projection Development Macromolecule Biosynthetic Process Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Neuron Death	Regulation Of Gene Expression Regulation Of Protein Phosphorylation Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Phosphorylation Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Transcription, DNA-templated Regulation Of Protein Kinase Activity Regulation Of Nitrogen Compound Metabolic Process RNA Biosynthetic Process Regulation Of Metabolic Process Regulation Of Kinase Activity Positive Regulation Of Transcription, DNA-templated Regulation Of Phosphorus Metabolic Process RNA Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Gene Expression Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Cell Cycle Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Tyrosine Kinase Activity Negative Regulation Of Cellular Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Cell Proliferation Negative Regulation Of Phosphorylation Cellular Nitrogen Compound Metabolic Process Immune System Process Transcription From RNA Polymerase II Promoter Cell Cycle Process Evasion Or Tolerance Of Host Defenses By Virus Regulation Of Cellular Process Regulation Of Cell Cycle Response To Organic Substance Organelle Organization Cellular Macromolecule Biosynthetic Process Positive Regulation Of Extracellular Matrix Assembly Positive Regulation Of Metabolic Process Negative Regulation Of Cell Proliferation Positive Regulation Of MAP Kinase Activity Nitrogen Compound Metabolic Process Negative Regulation Of Protein Phosphorylation
Tagcloud ?		1r additive additively attractive benefit cancers co combined depends depleted develops dimensional directed exist her2 her3 interestingly partners powerful promoting reveals rnai simultaneously stronger successfully tumour tumourigenesis tumours xenografts
Tagcloud (Difference) ?		1r additive additively attractive benefit cancers co combined depends depleted develops dimensional directed exist her2 her3 interestingly partners powerful promoting reveals rnai simultaneously stronger successfully tumour tumourigenesis tumours xenografts
Tagcloud (Intersection) ?