PTK6

Gene Name		protein tyrosine kinase 6
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Gene Ontology Annotations	Cellular Component	Ruffle Nucleus Nucleoplasm Cytoplasm Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
	Molecular Function	Non-membrane Spanning Protein Tyrosine Kinase Activity Receptor Binding Protein Binding ATP Binding Identical Protein Binding
	Biological Process	Protein Phosphorylation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Neuron Projection Development Cell Migration Actin Cytoskeleton Organization Peptidyl-tyrosine Autophosphorylation Regulation Of Cell Proliferation Tyrosine Phosphorylation Of Stat3 Protein Tyrosine Phosphorylation Of Stat5 Protein Innate Immune Response Negative Regulation Of Growth Protein Autophosphorylation Intestinal Epithelial Cell Differentiation Negative Regulation Of Protein Tyrosine Kinase Activity Cellular Response To Retinoic Acid
Pathways
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)
Protein-protein Interactions		14 interactors: APP CCDC33 DOK1 EFHC2 EGFR ERBB3 EXOC5 FCHO1 FGFR1 KHDRBS1 KHDRBS2 REL STAP2 WASL
Entrez ID		5753
HPRD ID		03594
Ensembl ID		ENSG00000101213
Uniprot IDs		Q13882
PDB IDs		1RJA 2KGT
Enriched GO Terms of Interacting Partners?		Innate Immune Response Fc Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Protein Metabolic Process Immune Response Defense Response Immune Response-regulating Cell Surface Receptor Signaling Pathway Axon Guidance Enzyme Linked Receptor Protein Signaling Pathway Phosphatidylinositol-mediated Signaling Immune Response-regulating Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Axonogenesis Response To Fibroblast Growth Factor Positive Regulation Of Cellular Protein Metabolic Process Axon Development Regulation Of Peptidyl-tyrosine Phosphorylation Cell Morphogenesis Involved In Neuron Differentiation Neurotrophin TRK Receptor Signaling Pathway Chemotaxis Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Signal Transduction Neuron Projection Morphogenesis Immune System Process Salivary Gland Morphogenesis Regulation Of Protein Metabolic Process Salivary Gland Development Cell Morphogenesis Involved In Differentiation Peptidyl-tyrosine Phosphorylation Regulation Of Protein Kinase Activity Positive Regulation Of Cell Cycle Gene Expression Exocrine System Development Positive Regulation Of Phospholipase C Activity Regulation Of Nitrogen Compound Metabolic Process Neuron Apoptotic Process Regulation Of Kinase Activity Cellular Macromolecule Biosynthetic Process Positive Regulation Of Intracellular Signal Transduction Regulation Of Protein Tyrosine Kinase Activity Neuron Projection Development Macromolecule Biosynthetic Process Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Neuron Death
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