AHSA1 and FILNC1

Number of citations of the paper that reports this interaction (PubMedID 28978906)
44

Data Source:
BioGRID (unspecified method)

		AHSA1	FILNC1
Description		activator of HSP90 ATPase activity 1	FOXO induced long non-coding RNA 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Cytosol Extracellular Exosome
	Molecular Function	ATPase Activator Activity Protein Binding Protein Folding Chaperone Cadherin Binding Unfolded Protein Binding Protein-folding Chaperone Binding Hsp90 Protein Binding
	Biological Process	Protein Folding Positive Regulation Of ATP-dependent Activity Maintenance Of Unfolded Protein
Pathways
Drugs
Diseases
GWAS			Heel bone mineral density x serum urate levels interaction ( 34046847)
Interacting Genes		12 interacting genes: AKT1 APP CEBPA CLCN1 EGFR FILNC1 FKBP4 GCH1 HSP90AA1 OGT PTGES3 USP40	88 interacting genes: AAAS ABCC1 ACTN1 ACTR2 AHSA1 AIMP2 AKAP8 ALDH1B1 AP1B1 AP3D1 ARAP1 ARF6 ATP2A2 CAND1 CCT6B CLPX CNDP2 COPG1 DDX24 DNM1 DNM1L DPM1 DYNC1H1 EEF1D EEF2 ERLIN1 GALK1 GMPS GSTO1 HDLBP HNRNPA0 HNRNPD HSPA1A IDH1 KTN1 LAMC1 LAS1L MAP1S MCM3 MRPL4 MSH2 MTHFD1L MYL12A NIBAN2 NKRF NOP56 NPEPPSP1 NSF NUP153 OASL OGT PCAT1 PDCD4 PES1 PFAS PLS3 PPME1 PSMC2 PSMC4 PSMD14 PSMD5 PURA QNG1 RIGI RO60 RPL13A RPS5 RPSA SART1 STT3B STXBP2 TAGLN2 TIMM50 TMEM126A TMX3 TRIP13 TTLL12 TTN U2AF1 UBA52 UBE4A VPS35 WARS1 XPO1 XPOT XRCC6 YWHAB ZCCHC8
Entrez ID		10598	100132735
HPRD ID		09768
Ensembl ID		ENSG00000100591	ENSG00000231426
Uniprot IDs		G3V438 O95433
PDB IDs		1X53 7DMD 7DME
Enriched GO Terms of Interacting Partners?		Protein-containing Complex Regulation Of Protein Catabolic Process Reactive Nitrogen Species Metabolic Process Nitric Oxide Metabolic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Nitric Oxide Metabolic Process Protein Homodimerization Activity Positive Regulation Of Proteolysis Nitric-oxide Synthase Regulator Activity Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Protein Metabolic Process Positive Regulation Of Protein Catabolic Process Regulation Of Nitric Oxide Metabolic Process Telomerase Holoenzyme Complex Assembly Response To UV-A Positive Regulation Of DNA Metabolic Process Kinase Binding Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Mitotic Cell Cycle Regulation Of Biological Quality Regulation Of Proteolysis Response To Tumor Necrosis Factor Regulation Of Generation Of Precursor Metabolites And Energy Positive Regulation Of Peptidyl-serine Phosphorylation Nitric Oxide Biosynthetic Process Chaperone-mediated Protein Complex Assembly Telomere Maintenance Via Telomerase DNA Polymerase Binding Positive Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Nucleobase-containing Compound Metabolic Process Embryonic Placenta Development Axonal Growth Cone RNA-templated DNA Biosynthetic Process Positive Regulation Of Telomere Maintenance Via Telomere Lengthening Regulation Of Protein Localization To Cell Periphery Regulation Of Protein Localization To Nucleus Regulation Of Peptidyl-serine Phosphorylation Regulation Of Ubiquitin-dependent Protein Catabolic Process Embryonic Organ Development Regulation Of Protein Localization To Membrane Positive Regulation Of Defense Response Positive Regulation Of Protein Localization Cellular Response To Metal Ion Regulation Of Superoxide Metabolic Process System Process Nervous System Process Telomere Maintenance Via Telomere Lengthening Protein Folding Chaperone Complex Regulation Of Protein Localization Regulation Of Protein Metabolic Process	RNA Binding Cytosol ATP Hydrolysis Activity Nucleotide Binding Cadherin Binding Ribonucleoprotein Complex Ficolin-1-rich Granule Lumen ATP Binding Extracellular Exosome Proteasome Accessory Complex Cytoplasm Translation Intracellular Transport Proteasome Regulatory Particle, Base Subcomplex Secretory Granule Lumen Nucleoplasm Actin Filament Binding Macromolecule Metabolic Process Nucleolus Mitochondrion-derived Vesicle Intracellular Protein Transport Organelle Localization Cellular Localization Establishment Of Localization In Cell Proteasome Complex Nucleobase-containing Compound Metabolic Process Actin Filament Network Formation ATP-dependent Protein Disaggregase Activity Proteasome-activating Activity LncRNA Binding Membrane Coat Ribosome Cytoplasmic Translation Establishment Of Organelle Localization Double-stranded DNA Binding Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Catabolic Process Establishment Of Protein Localization ATP-dependent Protein Folding Chaperone Cellular Component Assembly Regulation Of Cytoplasmic Translation
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