CCT7 and MED31

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CCT7	MED31
Gene Name		chaperonin containing TCP1, subunit 7 (eta)	mediator complex subunit 31
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Zona Pellucida Receptor Complex Cytoplasm Mitochondrion Cytosol Chaperonin-containing T-complex Microtubule Cell Body Extracellular Vesicular Exosome	Nucleoplasm Mediator Complex
	Molecular Function	Protein Binding ATP Binding Identical Protein Binding Unfolded Protein Binding	RNA Polymerase II Transcription Cofactor Activity Protein Binding Protein Complex Binding
	Biological Process	Protein Folding Binding Of Sperm To Zona Pellucida Cellular Protein Metabolic Process 'de Novo' Posttranslational Protein Folding Toxin Transport	Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Protein Complex Assembly Gene Expression Negative Regulation Of Fibroblast Proliferation Limb Development
Pathways		Protein folding Prefoldin mediated transfer of substrate to CCT/TriC Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding Association of TriC/CCT with target proteins during biosynthesis Chaperonin-mediated protein folding Formation of tubulin folding intermediates by CCT/TriC Folding of actin by CCT/TriC	PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: ANXA1 ANXA7 APP ATP5C1 CDKN1A CEBPE CRMP1 DNM2 EEF1G KAT5 KRAS MED31 NKX3-1 PRPF40A RAP1B RCC1 SSSCA1 SUMO4 TCP1	58 interactors: AES AGR2 ANXA7 ASCC2 C2orf44 CACNB4 CCT7 CDKN1A CPE DAZAP2 DLEU1 DNM1 EEF1G EGR2 EPN1 ERH FAM118B GADD45G GSTM4 HGH1 HMOX2 HNRNPUL1 HSPB1 HSPB3 HTT LAMA4 LYPLA2 MAFG MED18 MED19 MED7 MED8 MED9 MOB4 NFATC2 NR4A1 ORAI2 PABPC4 PAFAH1B3 PFDN1 PMF1 PQBP1 PRMT1 PSMD11 RAB25 RBM23 RFC5 RPA2 SAT1 SELENBP1 SERPINB9 SMN1 TGIF1 TINAGL1 TK1 UBE2B ZBTB45 ZSCAN1
Entrez ID		10574	51003
HPRD ID		06896	14382
Ensembl ID		ENSG00000135624	ENSG00000108590
Uniprot IDs		Q99832	Q9Y3C7
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Organic Cyclic Compound Response To Abiotic Stimulus Regulation Of Mitotic Cell Cycle Response To Radiation Response To Steroid Hormone Regulation Of Cell Cycle Process Response To Lipid Regulation Of Cell Cycle Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Cell Cycle Mitotic Cell Cycle Arrest Positive Regulation Of Metabolic Process Positive Regulation Of Mitotic Cell Cycle Epithelium Development Positive Regulation Of Cellular Protein Metabolic Process Response To Ionizing Radiation Regulation Of Protein Kinase Activity Cellular Response To Organic Cyclic Compound Cellular Metabolic Process Response To Glucocorticoid Regulation Of Catalytic Activity Positive Regulation Of Protein Metabolic Process Response To X-ray Cellular Response To Lipid Response To Corticosteroid Regulation Of Kinase Activity Hemostasis Regulation Of Myeloid Cell Apoptotic Process Anatomical Structure Development Cellular Response To Steroid Hormone Stimulus Cellular Response To Organic Substance Response To Organic Substance Positive Regulation Of Protein Kinase Activity Regulation Of Nitric-oxide Synthase Activity Response To Mineralocorticoid Cell Cycle Regulation Of Cellular Component Organization Androgen Receptor Signaling Pathway Social Behavior Intracellular Receptor Signaling Pathway Positive Regulation Of Kinase Activity Cell Differentiation Positive Regulation Of Protein Modification Process Response To Stress Regulation Of Apoptotic Process Ras Protein Signal Transduction Regulation Of Mitotic Cell Cycle Phase Transition Response To Hormone Positive Regulation Of Cell Cycle Process Neurotrophin Signaling Pathway	Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Gene Expression Cellular Metabolic Process Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transcription, DNA-templated RNA Metabolic Process RNA Biosynthetic Process Developmental Process Biosynthetic Process Regulation Of Gene Expression Anatomical Structure Development Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cell Differentiation Multicellular Organismal Development Response To Stimulus Neurotransmitter Uptake Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Nucleotide-excision Repair, DNA Gap Filling Negative Regulation Of Apoptotic Process Regulation Of RNA Metabolic Process Negative Regulation Of Programmed Cell Death Telomere Maintenance Via Semi-conservative Replication System Development Regulation Of Metabolic Process Regulation Of Apoptotic Process Negative Regulation Of Cell Death Telomere Maintenance Via Recombination Nuclear DNA Replication Mitotic DNA Damage Checkpoint Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Mitotic DNA Integrity Checkpoint Embryo Development Ending In Birth Or Egg Hatching DNA-templated Transcription, Initiation Response To External Stimulus Regulation Of Cell Death Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Protein Metabolic Process
Tagcloud ?		adequately cct3 cct5 crc csnk2a2 discover discriminative gna12 hypotheses ifitm1 igfbp3 integrating legacy merely merit mutual outlines pdgfrb plk1 proteomics proxy pruned resultant scheme scoring sized subnetwork subnetworks wealth
Tagcloud (Difference) ?		adequately cct3 cct5 crc csnk2a2 discover discriminative gna12 hypotheses ifitm1 igfbp3 integrating legacy merely merit mutual outlines pdgfrb plk1 proteomics proxy pruned resultant scheme scoring sized subnetwork subnetworks wealth
Tagcloud (Intersection) ?