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TRIM38 and TCEA2
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
TRIM38
TCEA2
Description
tripartite motif containing 38
transcription elongation factor A2
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Nucleus
Nucleoplasm
Centrosome
Transcription Elongation Factor Complex
Ciliary Basal Body
Molecular Function
Transcription Coactivator Activity
Protein Binding
Zinc Ion Binding
Transferase Activity
Metal Ion Binding
Ubiquitin Protein Ligase Activity
Nucleic Acid Binding
DNA Binding
Protein Binding
Zinc Ion Binding
Metal Ion Binding
Biological Process
Immune System Process
Regulation Of Gene Expression
Protein Ubiquitination
Protein Sumoylation
Regulation Of Interferon-beta Production
Positive Regulation Of Canonical NF-kappaB Signal Transduction
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Viral Genome Replication
Innate Immune Response
Positive Regulation Of DNA-templated Transcription
Regulation Of Viral Entry Into Host Cell
Positive Regulation Of Viral Entry Into Host Cell
Positive Regulation Of Viral Process
Negative Regulation Of Defense Response To Virus
Protein K48-linked Ubiquitination
Regulation Of Viral Life Cycle
DNA-templated Transcription
DNA-templated Transcription Elongation
Regulation Of Transcription By RNA Polymerase II
Transcription Elongation By RNA Polymerase II
Regulation Of DNA-templated Transcription Elongation
Pathways
Interferon gamma signaling
Drugs
Diseases
GWAS
A body shape index (
34021172
)
Autism spectrum disorder or schizophrenia (
28540026
)
Brain morphology (MOSTest) (
32665545
)
Cardiac hypertrophy (
21348951
)
Fish- and plant-related diet (
32066663
)
Height (
28552196
)
Iron status biomarkers (
19084217
)
Lung cancer (
28604730
)
Lung cancer in ever smokers (
28604730
)
Refractive error (
32231278
)
Subcortical volume (MOSTest) (
32665545
)
Adult body size (
32376654
)
Adventurousness (
30643258
)
Alanine aminotransferase levels (
34315874
)
Anxiety (
31906708
)
Aspartate aminotransferase levels (
34315874
)
Cerebrospinal AB1-42 levels in normal cognition (
29274321
)
Eosinophil count (
32888494
)
Hip index (
34021172
)
Low density lipoprotein cholesterol levels (
32154731
)
Pulse pressure (
30578418
27841878
)
Serum thyroid-stimulating hormone levels (
25436638
)
Systolic blood pressure (
27841878
)
Triglyceride levels (
29083408
)
Type 2 diabetes (adjusted for BMI) (
30297969
)
Waist-hip index (
34021172
)
Waist-to-hip ratio adjusted for BMI (
34021172
)
Interacting Genes
30 interacting genes:
ATXN1
BYSL
EIF1B
GMCL1
GORASP2
HSPA1A
HSPA1B
HSPA1L
HSPA2
HSPA8
MTURN
PIAS4
PSMA4
RFC5
RIPK1
RNF4
SDCBP
STXBP1
TCEA2
TSPYL4
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2I
UBE2U
ZNF764
134 interacting genes:
ADAMTSL4
AGR2
AGTRAP
AKT1S1
ALAS1
AMOTL2
APP
ARMC10
AXIN2
BACH2
BICD2
BOLL
BRCA1
BTBD6
CAMKV
CBY2
CCDC136
CCDC157
CCSER2
CDK11B
CENPT
CEP44
CEP70
CEP76
CMTM4
CMTM6
CNTROB
COX20
CYSRT1
DAB1
DCAF10
DES
DHRS2
DNAJB9
DRC4
DVL3
EAF1
EAF2
ERBB3
EXOSC8
FADD
FAM9B
FBF1
FCHO1
FXR1
GIGYF1
GOLGA2
GPKOW
GPRASP3
GRIPAP1
GTF2B
HES7
HIGD1C
HIP1
HMBOX1
HOMEZ
HOOK2
HSF2BP
IKZF1
IKZF4
KCNF1
KCTD10
KCTD7
KIAA1958
KRT40
KRTAP10-7
KRTAP10-8
KRTAP12-2
KRTAP12-3
KRTAP5-9
KXD1
LIMS1
LMNA
LRRK2
LZTS1
LZTS2
MAGEA11
MARK3
MCC
MCM2
MDK
MEOX2
MID2
MKRN3
MSANTD4
MTUS2
NAB2
NECAB1
NECAB2
OSBPL3
PIBF1
PICK1
PIH1D2
PNMA1
PNMA5
POU6F2
PRPH
RBPMS
RETREG3
RPA1
SCYL1
SH3GL2
SSC5D
STAC3
STX11
SYNE4
TARBP2
TAX1BP1
TAX1BP3
TBC1D1
TCF4
TEPSIN
TFCP2
THAP1
TMEM71
TNIP1
TOX2
TRAF1
TRAF2
TRIM23
TRIM27
TRIM38
TRIM41
TRIM54
TSGA10
USP54
VIM
WDR47
ZBTB22
ZBTB43
ZBTB8A
ZBTB9
ZKSCAN8
ZNF526
Entrez ID
10475
6919
HPRD ID
15555
16069
Ensembl ID
ENSG00000112343
ENSG00000171703
Uniprot IDs
O00635
Q15560
Q6IB64
PDB IDs
2LW4
Enriched GO Terms of Interacting Partners
?
Ubiquitin Conjugating Enzyme Activity
Protein K48-linked Ubiquitination
ATP Binding
Protein Refolding
Protein Polyubiquitination
ATP-dependent Protein Folding Chaperone
Protein K11-linked Ubiquitination
Ubiquitin-protein Transferase Activity
Nucleotide Binding
Macromolecule Catabolic Process
Protein Modification By Small Protein Conjugation
C3HC4-type RING Finger Domain Binding
Protein Folding Chaperone
Blood Microparticle
ATP-dependent Protein Disaggregase Activity
Heat Shock Protein Binding
Post-translational Protein Modification
Response To Unfolded Protein
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Negative Regulation Of Inclusion Body Assembly
Protein Ubiquitination
Unfolded Protein Binding
Nucleus
Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Protein Monoubiquitination
Proteolysis Involved In Protein Catabolic Process
Protein Modification Process
Nucleoplasm
Regulation Of Inclusion Body Assembly
Macromolecule Metabolic Process
Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Transferase Activity
Protein K63-linked Ubiquitination
Protein K6-linked Ubiquitination
Cellular Response To Steroid Hormone Stimulus
ISG15 Transferase Activity
Ubiquitin Protein Ligase Binding
Cellular Response To Stress
Regulation Of Spindle Assembly
Catabolic Process
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Protein Metabolic Process
Protein Folding
Positive Regulation Of Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway
Cellular Heat Acclimation
Negative Regulation Of Protein Localization To Chromatin
ISG15-protein Conjugation
Positive Regulation Of Myeloid Cell Differentiation
ATP Hydrolysis Activity
Identical Protein Binding
Protein Binding
Intermediate Filament
Cytosol
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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