TCEA2 and TAX1BP3

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TCEA2	TAX1BP3
Description		transcription elongation factor A2	Tax1 binding protein 3
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Centrosome Transcription Elongation Factor Complex Ciliary Basal Body	Fibrillar Center Nucleus Cytoplasm Cytosol Plasma Membrane Actin Cytoskeleton Membrane Extracellular Exosome
	Molecular Function	Nucleic Acid Binding DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding Beta-catenin Binding
	Biological Process	DNA-templated Transcription DNA-templated Transcription Elongation Regulation Of Transcription By RNA Polymerase II Transcription Elongation By RNA Polymerase II Regulation Of DNA-templated Transcription Elongation	Rho Protein Signal Transduction Negative Regulation Of Cell Population Proliferation Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Regulation Of Cdc42 Protein Signal Transduction Negative Regulation Of Protein Localization To Cell Surface
Pathways			RHO GTPases Activate Rhotekin and Rhophilins
Drugs
Diseases
GWAS		Adult body size ( 32376654) Adventurousness ( 30643258) Alanine aminotransferase levels ( 34315874) Anxiety ( 31906708) Aspartate aminotransferase levels ( 34315874) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Eosinophil count ( 32888494) Hip index ( 34021172) Low density lipoprotein cholesterol levels ( 32154731) Pulse pressure ( 30578418 27841878) Serum thyroid-stimulating hormone levels ( 25436638) Systolic blood pressure ( 27841878) Triglyceride levels ( 29083408) Type 2 diabetes (adjusted for BMI) ( 30297969) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		134 interacting genes: ADAMTSL4 AGR2 AGTRAP AKT1S1 ALAS1 AMOTL2 APP ARMC10 AXIN2 BACH2 BICD2 BOLL BRCA1 BTBD6 CAMKV CBY2 CCDC136 CCDC157 CCSER2 CDK11B CENPT CEP44 CEP70 CEP76 CMTM4 CMTM6 CNTROB COX20 CYSRT1 DAB1 DCAF10 DES DHRS2 DNAJB9 DRC4 DVL3 EAF1 EAF2 ERBB3 EXOSC8 FADD FAM9B FBF1 FCHO1 FXR1 GIGYF1 GOLGA2 GPKOW GPRASP3 GRIPAP1 GTF2B HES7 HIGD1C HIP1 HMBOX1 HOMEZ HOOK2 HSF2BP IKZF1 IKZF4 KCNF1 KCTD10 KCTD7 KIAA1958 KRT40 KRTAP10-7 KRTAP10-8 KRTAP12-2 KRTAP12-3 KRTAP5-9 KXD1 LIMS1 LMNA LRRK2 LZTS1 LZTS2 MAGEA11 MARK3 MCC MCM2 MDK MEOX2 MID2 MKRN3 MSANTD4 MTUS2 NAB2 NECAB1 NECAB2 OSBPL3 PIBF1 PICK1 PIH1D2 PNMA1 PNMA5 POU6F2 PRPH RBPMS RETREG3 RPA1 SCYL1 SH3GL2 SSC5D STAC3 STX11 SYNE4 TARBP2 TAX1BP1 TAX1BP3 TBC1D1 TCF4 TEPSIN TFCP2 THAP1 TMEM71 TNIP1 TOX2 TRAF1 TRAF2 TRIM23 TRIM27 TRIM38 TRIM41 TRIM54 TSGA10 USP54 VIM WDR47 ZBTB22 ZBTB43 ZBTB8A ZBTB9 ZKSCAN8 ZNF526	14 interacting genes: ARHGEF16 ARNT2 CDK5RAP3 CTNNB1 DTX1 GATA1 GLS GLS2 PLK4 RNF183 RTKN STAU1 TCEA2 TRIM29
Entrez ID		6919	30851
HPRD ID		16069	18160
Ensembl ID		ENSG00000171703	ENSG00000213977
Uniprot IDs		Q15560 Q6IB64	A0A087X282 O14907
PDB IDs		2LW4	2KG2 2L4S 2L4T 2VZ5 3GJ9 3SFJ 4E3B 4NNL 4NNM
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Protein Binding Intermediate Filament Cytosol	L-glutamine Catabolic Process Glutaminase Activity Glutamate Biosynthetic Process Glutamine Metabolic Process Transcription Regulator Complex DNA-templated Transcription Mesenchymal Stem Cell Differentiation Positive Regulation Of Determination Of Dorsal Identity Negative Regulation Of Mitotic Cell Cycle, Embryonic Centrosome Beta-catenin-ICAT Complex Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Glial Cell Fate Determination Protein-DNA Complex Renal Inner Medulla Development In Utero Embryonic Development Scrib-APC-beta-catenin Complex Regulation Of Apoptotic Process Embryo Development Ending In Birth Or Egg Hatching Multicellular Organism Development Renal Outer Medulla Development Transcription Coregulator Binding Renal Vesicle Formation Canonical Wnt Signaling Pathway Involved In Mesenchymal Stem Cell Differentiation Myeloid Cell Differentiation Chordate Embryonic Development Positive Regulation Of Branching Involved In Lung Morphogenesis Neural Plate Development Regulation Of Glycoprotein Biosynthetic Process Regulation Of Programmed Cell Death Transcription By RNA Polymerase II Basophil Differentiation P53 Binding Eosinophil Fate Commitment Regulation Of Primitive Erythrocyte Differentiation Erythrocyte Differentiation Glutamate Metabolic Process Amino Acid Biosynthetic Process Glutamine Family Amino Acid Metabolic Process Septin Ring Organization Oviduct Development Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Mononuclear Cell Differentiation Protein Modification By Small Protein Conjugation Fungiform Papilla Formation Beta-catenin-TCF7L2 Complex Astrocyte-dopaminergic Neuron Signaling Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Regulation Of Centriole-centriole Cohesion Embryonic Skeletal Limb Joint Morphogenesis
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