TCEA2 and CDK11B

Number of citations of the paper that reports this interaction (PMID 11709559)
18

Data Source:
HPRD (in vitro)

		TCEA2	CDK11B
Gene Name		transcription elongation factor A (SII), 2	cyclin-dependent kinase 11B
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Centrosome Transcription Elongation Factor Complex	Nucleus Cytoplasm
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Poly(A) RNA Binding
	Biological Process	DNA-templated Transcription, Elongation Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Transcription From RNA Polymerase II Promoter	Regulation Of Cell Growth Regulation Of Transcription, DNA-templated Protein Phosphorylation Apoptotic Process Mitotic Nuclear Division Cell Proliferation Regulation Of MRNA Processing Regulation Of Cell Cycle
Pathways			G2/M Transition Centrosome maturation Mitotic G2-G2/M phases Cell Cycle, Mitotic Recruitment of mitotic centrosome proteins and complexes
Drugs
Diseases
GWAS
Protein-Protein Interactions		47 interactors: ADAMTSL4 AKT1S1 ALAS1 APP BRCA1 CAMKV CCDC136 CCSER2 CDK11B CENPT CEP44 DAB1 DCAF10 DHRS2 DNAJB9 EAF2 EXOSC8 FAM9B FBF1 GOLGA2 GPKOW GRIPAP1 GTF2B KIAA1958 KRT40 KRTAP10-7 KRTAP5-9 LZTS2 MAGEA11 MARK3 MCM2 MEOX2 MID2 MKRN3 RPA1 SH3GL2 TAX1BP1 TAX1BP3 TCF4 TFCP2 THAP1 TNIP1 TRAF2 TRIM27 TRIM54 TSGA10 WDR47	22 interactors: AP2M1 CASP1 CASP3 CASP8 CCND3 CCNL2 EIF3F KAT7 MSN PAK1 PIN1 RANBP9 RPS27A TCEA2 TH TPPP URM1 YWHAB YWHAE YWHAG YWHAQ YWHAZ
Entrez ID		6919	984
HPRD ID		16069	08909
Ensembl ID		ENSG00000171703	ENSG00000248333
Uniprot IDs		Q15560 Q6IB64 Q86VL0	P21127
PDB IDs		2LW4
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Binding Protein-DNA Complex Assembly Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cell Death Death Cell Cycle Negative Regulation Of Viral Process Protein Ubiquitination Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Signal Transduction Protein Modification By Small Protein Conjugation Cellular Macromolecular Complex Assembly Negative Regulation Of Signaling Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell Cellular Component Assembly Regulation Of Binding Apoptotic Process DNA Strand Elongation Involved In DNA Replication Regulation Of Phosphorylation Programmed Cell Death Regulation Of Protein Kinase Activity Regulation Of Cellular Response To Heat DNA Strand Elongation Mitotic Cell Cycle Cell Cycle Process Protein K63-linked Ubiquitination Protein Trimerization Regulation Of Kinase Activity Positive Regulation Of Histone H4-K20 Methylation Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Positive Regulation Of Histone H4-K16 Acetylation Innate Immune Response Immune System Process Protein Autoubiquitination Regulation Of Viral Process Regulation Of Phosphorus Metabolic Process Response To Stress Cellular Response To Stress Protein Polyubiquitination Cerebellum Structural Organization Negative Regulation Of Interleukin-2 Secretion Synaptic Growth At Neuromuscular Junction Positive Regulation Of Histone H3-K9 Acetylation Catenin Import Into Nucleus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Wnt Signaling Pathway Regulation Of Signal Transduction	Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Regulation Of Mitochondrion Organization Intrinsic Apoptotic Signaling Pathway Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Apoptotic Process Programmed Cell Death Cell Death Death Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Organelle Organization Protein Targeting Positive Regulation Of Intracellular Transport Regulation Of Protein Metabolic Process Cellular Response To Organic Substance Regulation Of Cellular Component Organization Regulation Of Protein Localization Membrane Organization Intracellular Protein Transport Positive Regulation Of Signal Transduction Regulation Of Organelle Organization Immune System Process Neurotrophin TRK Receptor Signaling Pathway Cellular Protein Localization Neurotrophin Signaling Pathway Regulation Of Establishment Of Protein Localization Regulation Of Intracellular Transport Regulation Of Cellular Localization Regulation Of Catalytic Activity Hippo Signaling Regulation Of Apoptotic Process Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Positive Regulation Of Transport Regulation Of Phosphorus Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Establishment Of Localization In Cell Response To Organic Substance Regulation Of Cell Death Regulation Of Kinase Activity Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Positive Regulation Of Protein Metabolic Process Regulation Of Signal Transduction Cellular Response To Growth Factor Stimulus
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