TCEA2 and GPRASP3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TCEA2	GPRASP3
Description		transcription elongation factor A2	G protein-coupled receptor associated sorting protein family member 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Centrosome Transcription Elongation Factor Complex Ciliary Basal Body	Nucleus Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Nucleic Acid Binding DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding Protein Homodimerization Activity
	Biological Process	DNA-templated Transcription DNA-templated Transcription Elongation Regulation Of Transcription By RNA Polymerase II Transcription Elongation By RNA Polymerase II Regulation Of DNA-templated Transcription Elongation	Learning Or Memory Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Neurogenesis Positive Regulation Of Synapse Assembly Positive Regulation Of Dendritic Spine Morphogenesis
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Adventurousness ( 30643258) Alanine aminotransferase levels ( 34315874) Anxiety ( 31906708) Aspartate aminotransferase levels ( 34315874) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Eosinophil count ( 32888494) Hip index ( 34021172) Low density lipoprotein cholesterol levels ( 32154731) Pulse pressure ( 30578418 27841878) Serum thyroid-stimulating hormone levels ( 25436638) Systolic blood pressure ( 27841878) Triglyceride levels ( 29083408) Type 2 diabetes (adjusted for BMI) ( 30297969) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		134 interacting genes: ADAMTSL4 AGR2 AGTRAP AKT1S1 ALAS1 AMOTL2 APP ARMC10 AXIN2 BACH2 BICD2 BOLL BRCA1 BTBD6 CAMKV CBY2 CCDC136 CCDC157 CCSER2 CDK11B CENPT CEP44 CEP70 CEP76 CMTM4 CMTM6 CNTROB COX20 CYSRT1 DAB1 DCAF10 DES DHRS2 DNAJB9 DRC4 DVL3 EAF1 EAF2 ERBB3 EXOSC8 FADD FAM9B FBF1 FCHO1 FXR1 GIGYF1 GOLGA2 GPKOW GPRASP3 GRIPAP1 GTF2B HES7 HIGD1C HIP1 HMBOX1 HOMEZ HOOK2 HSF2BP IKZF1 IKZF4 KCNF1 KCTD10 KCTD7 KIAA1958 KRT40 KRTAP10-7 KRTAP10-8 KRTAP12-2 KRTAP12-3 KRTAP5-9 KXD1 LIMS1 LMNA LRRK2 LZTS1 LZTS2 MAGEA11 MARK3 MCC MCM2 MDK MEOX2 MID2 MKRN3 MSANTD4 MTUS2 NAB2 NECAB1 NECAB2 OSBPL3 PIBF1 PICK1 PIH1D2 PNMA1 PNMA5 POU6F2 PRPH RBPMS RETREG3 RPA1 SCYL1 SH3GL2 SSC5D STAC3 STX11 SYNE4 TARBP2 TAX1BP1 TAX1BP3 TBC1D1 TCF4 TEPSIN TFCP2 THAP1 TMEM71 TNIP1 TOX2 TRAF1 TRAF2 TRIM23 TRIM27 TRIM38 TRIM41 TRIM54 TSGA10 USP54 VIM WDR47 ZBTB22 ZBTB43 ZBTB8A ZBTB9 ZKSCAN8 ZNF526	59 interacting genes: ANKRD11 APP AQP1 ATOSB BEX2 CATSPERT CCDC120 CDC23 CDC37 CDCA7L CT55 DDX6 DRC4 EAF1 EIF3B ENKD1 FAM124B FAM161A FAM90A1 GEM GPANK1 HOXA1 INO80B IPO5 IQUB KLHL38 L3MBTL2 LEO1 LMO1 LONRF1 MFAP1 MISP MPP1 MYO15B NRIP1 OTX1 PALS1 PHF1 PNMA5 POLR1C PPP2R5E PRKAB2 PRPF31 RCOR3 SCNM1 SH3KBP1 SMARCD1 SPANXN2 TASOR2 TCEA2 TEPSIN THOC1 TLK1 TOP3B TSGA10IP TXN2 USP2 USP20 ZNF417
Entrez ID		6919	80823
HPRD ID		16069	10028
Ensembl ID		ENSG00000171703	ENSG00000198908
Uniprot IDs		Q15560 Q6IB64	Q6PI77
PDB IDs		2LW4
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Protein Binding Intermediate Filament Cytosol
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