TCEA2 and DHRS2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		TCEA2	DHRS2
Gene Name		transcription elongation factor A (SII), 2	dehydrogenase/reductase (SDR family) member 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Centrosome Transcription Elongation Factor Complex	Nucleus Nuclear Envelope Cytoplasm Mitochondrion Mitochondrial Matrix Extracellular Vesicular Exosome
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding	Carbonyl Reductase (NADPH) Activity
	Biological Process	DNA-templated Transcription, Elongation Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Transcription From RNA Polymerase II Promoter	C21-steroid Hormone Metabolic Process Negative Regulation Of Cell Proliferation Response To Toxic Substance Cellular Response To Oxidative Stress Myeloid Dendritic Cell Differentiation Negative Regulation Of Apoptotic Process Oxidation-reduction Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		47 interactors: ADAMTSL4 AKT1S1 ALAS1 APP BRCA1 CAMKV CCDC136 CCSER2 CDK11B CENPT CEP44 DAB1 DCAF10 DHRS2 DNAJB9 EAF2 EXOSC8 FAM9B FBF1 GOLGA2 GPKOW GRIPAP1 GTF2B KIAA1958 KRT40 KRTAP10-7 KRTAP5-9 LZTS2 MAGEA11 MARK3 MCM2 MEOX2 MID2 MKRN3 RPA1 SH3GL2 TAX1BP1 TAX1BP3 TCF4 TFCP2 THAP1 TNIP1 TRAF2 TRIM27 TRIM54 TSGA10 WDR47	4 interactors: APPBP2 EXOSC5 TCEA2 ZHX2
Entrez ID		6919	10202
HPRD ID		16069	07483
Ensembl ID		ENSG00000171703	ENSG00000100867
Uniprot IDs		Q15560 Q6IB64 Q86VL0	Q13268
PDB IDs		2LW4
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Binding Protein-DNA Complex Assembly Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cell Death Death Cell Cycle Negative Regulation Of Viral Process Protein Ubiquitination Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Signal Transduction Protein Modification By Small Protein Conjugation Cellular Macromolecular Complex Assembly Negative Regulation Of Signaling Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell Cellular Component Assembly Regulation Of Binding Apoptotic Process DNA Strand Elongation Involved In DNA Replication Regulation Of Phosphorylation Programmed Cell Death Regulation Of Protein Kinase Activity Regulation Of Cellular Response To Heat DNA Strand Elongation Mitotic Cell Cycle Cell Cycle Process Protein K63-linked Ubiquitination Protein Trimerization Regulation Of Kinase Activity Positive Regulation Of Histone H4-K20 Methylation Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Positive Regulation Of Histone H4-K16 Acetylation Innate Immune Response Immune System Process Protein Autoubiquitination Regulation Of Viral Process Regulation Of Phosphorus Metabolic Process Response To Stress Cellular Response To Stress Protein Polyubiquitination Cerebellum Structural Organization Negative Regulation Of Interleukin-2 Secretion Synaptic Growth At Neuromuscular Junction Positive Regulation Of Histone H3-K9 Acetylation Catenin Import Into Nucleus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Wnt Signaling Pathway Regulation Of Signal Transduction	MRNA Catabolic Process RNA Catabolic Process DNA Deamination Aromatic Compound Catabolic Process MRNA Metabolic Process
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