TCEA2 and CENPT

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TCEA2	CENPT
Gene Name		transcription elongation factor A (SII), 2	centromere protein T
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Centrosome Transcription Elongation Factor Complex	Chromosome, Centromeric Region Kinetochore Condensed Chromosome Kinetochore Nucleus Nucleoplasm Cytosol
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding	DNA Binding Protein Binding Protein Heterodimerization Activity
	Biological Process	DNA-templated Transcription, Elongation Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Transcription From RNA Polymerase II Promoter	Mitotic Cell Cycle Nucleosome Assembly Chromosome Segregation Mitotic Nuclear Division CENP-A Containing Nucleosome Assembly Chromosome Organization Cell Division Kinetochore Assembly
Pathways			Mitotic Prometaphase Chromosome Maintenance Nucleosome assembly Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		47 interactors: ADAMTSL4 AKT1S1 ALAS1 APP BRCA1 CAMKV CCDC136 CCSER2 CDK11B CENPT CEP44 DAB1 DCAF10 DHRS2 DNAJB9 EAF2 EXOSC8 FAM9B FBF1 GOLGA2 GPKOW GRIPAP1 GTF2B KIAA1958 KRT40 KRTAP10-7 KRTAP5-9 LZTS2 MAGEA11 MARK3 MCM2 MEOX2 MID2 MKRN3 RPA1 SH3GL2 TAX1BP1 TAX1BP3 TCF4 TFCP2 THAP1 TNIP1 TRAF2 TRIM27 TRIM54 TSGA10 WDR47	6 interactors: APP COPS5 DHX29 PPCDC SNCB TCEA2
Entrez ID		6919	80152
HPRD ID		16069	07811
Ensembl ID		ENSG00000171703	ENSG00000102901
Uniprot IDs		Q15560 Q6IB64 Q86VL0	B3KPB2 Q96BT3
PDB IDs		2LW4
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Binding Protein-DNA Complex Assembly Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cell Death Death Cell Cycle Negative Regulation Of Viral Process Protein Ubiquitination Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Signal Transduction Protein Modification By Small Protein Conjugation Cellular Macromolecular Complex Assembly Negative Regulation Of Signaling Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell Cellular Component Assembly Regulation Of Binding Apoptotic Process DNA Strand Elongation Involved In DNA Replication Regulation Of Phosphorylation Programmed Cell Death Regulation Of Protein Kinase Activity Regulation Of Cellular Response To Heat DNA Strand Elongation Mitotic Cell Cycle Cell Cycle Process Protein K63-linked Ubiquitination Protein Trimerization Regulation Of Kinase Activity Positive Regulation Of Histone H4-K20 Methylation Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Positive Regulation Of Histone H4-K16 Acetylation Innate Immune Response Immune System Process Protein Autoubiquitination Regulation Of Viral Process Regulation Of Phosphorus Metabolic Process Response To Stress Cellular Response To Stress Protein Polyubiquitination Cerebellum Structural Organization Negative Regulation Of Interleukin-2 Secretion Synaptic Growth At Neuromuscular Junction Positive Regulation Of Histone H3-K9 Acetylation Catenin Import Into Nucleus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Wnt Signaling Pathway Regulation Of Signal Transduction	Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Translation Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Synapse Organization Exosomal Secretion Collateral Sprouting Axon Midline Choice Point Recognition Nucleobase-containing Compound Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Translational Initiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Axon Choice Point Recognition Heterocycle Metabolic Process Cullin Deneddylation Cellular Nitrogen Compound Metabolic Process Neuron Remodeling Protein Deneddylation Exocytosis Pantothenate Metabolic Process Positive Regulation Of Transcription, DNA-templated RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Coenzyme A Biosynthetic Process Cellular Copper Ion Homeostasis Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Gene Expression Copper Ion Homeostasis Suckling Behavior Cellular Metabolic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Secretion By Cell Coenzyme A Metabolic Process Dopamine Metabolic Process Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Regulation Of Transcription From RNA Polymerase II Promoter
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