TCEA2 and BTBD6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TCEA2	BTBD6
Description		transcription elongation factor A2	BTB domain containing 6
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Centrosome Transcription Elongation Factor Complex Ciliary Basal Body	Cytoplasm Cytosol
	Molecular Function	Nucleic Acid Binding DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding
	Biological Process	DNA-templated Transcription DNA-templated Transcription Elongation Regulation Of Transcription By RNA Polymerase II Transcription Elongation By RNA Polymerase II Regulation Of DNA-templated Transcription Elongation	Neurogenesis
Pathways			Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Adult body size ( 32376654) Adventurousness ( 30643258) Alanine aminotransferase levels ( 34315874) Anxiety ( 31906708) Aspartate aminotransferase levels ( 34315874) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Eosinophil count ( 32888494) Hip index ( 34021172) Low density lipoprotein cholesterol levels ( 32154731) Pulse pressure ( 30578418 27841878) Serum thyroid-stimulating hormone levels ( 25436638) Systolic blood pressure ( 27841878) Triglyceride levels ( 29083408) Type 2 diabetes (adjusted for BMI) ( 30297969) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		134 interacting genes: ADAMTSL4 AGR2 AGTRAP AKT1S1 ALAS1 AMOTL2 APP ARMC10 AXIN2 BACH2 BICD2 BOLL BRCA1 BTBD6 CAMKV CBY2 CCDC136 CCDC157 CCSER2 CDK11B CENPT CEP44 CEP70 CEP76 CMTM4 CMTM6 CNTROB COX20 CYSRT1 DAB1 DCAF10 DES DHRS2 DNAJB9 DRC4 DVL3 EAF1 EAF2 ERBB3 EXOSC8 FADD FAM9B FBF1 FCHO1 FXR1 GIGYF1 GOLGA2 GPKOW GPRASP3 GRIPAP1 GTF2B HES7 HIGD1C HIP1 HMBOX1 HOMEZ HOOK2 HSF2BP IKZF1 IKZF4 KCNF1 KCTD10 KCTD7 KIAA1958 KRT40 KRTAP10-7 KRTAP10-8 KRTAP12-2 KRTAP12-3 KRTAP5-9 KXD1 LIMS1 LMNA LRRK2 LZTS1 LZTS2 MAGEA11 MARK3 MCC MCM2 MDK MEOX2 MID2 MKRN3 MSANTD4 MTUS2 NAB2 NECAB1 NECAB2 OSBPL3 PIBF1 PICK1 PIH1D2 PNMA1 PNMA5 POU6F2 PRPH RBPMS RETREG3 RPA1 SCYL1 SH3GL2 SSC5D STAC3 STX11 SYNE4 TARBP2 TAX1BP1 TAX1BP3 TBC1D1 TCF4 TEPSIN TFCP2 THAP1 TMEM71 TNIP1 TOX2 TRAF1 TRAF2 TRIM23 TRIM27 TRIM38 TRIM41 TRIM54 TSGA10 USP54 VIM WDR47 ZBTB22 ZBTB43 ZBTB8A ZBTB9 ZKSCAN8 ZNF526	10 interacting genes: BTBD3 CUL3 DAXX FXR1 GRSF1 NFKBIB NME7 NTAQ1 PAXIP1 TCEA2
Entrez ID		6919	90135
HPRD ID		16069	12540
Ensembl ID		ENSG00000171703	ENSG00000184887
Uniprot IDs		Q15560 Q6IB64	A0A384NYR4 A0A8C8KHP4 Q96KE9
PDB IDs		2LW4	2VKP
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Protein Binding Intermediate Filament Cytosol	Ribonucleoprotein Granule Regulation Of Protein Ubiquitination Regulation Of Post-translational Protein Modification Molecular Condensate Scaffold Activity Nucleic Acid Metabolic Process Transcription Elongation By RNA Polymerase II DNA-templated Transcription Elongation Neuron Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Regulation Of RNA Metabolic Process Nucleus Cellular Response To Diamide Nucleobase-containing Compound Catabolic Process Nucleobase-containing Compound Biosynthetic Process Regulation Of Rho Protein Signal Transduction Trophectodermal Cellular Morphogenesis Liver Morphogenesis Protein-N-terminal Asparagine Amidohydrolase Activity Protein-N-terminal Glutamine Amidohydrolase Activity Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Mitochondrial RNA Catabolic Process Nucleobase-containing Compound Metabolic Process DNA-templated Transcription Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Regulation Protein Catabolic Process At Postsynapse Positive Regulation Of Protein Ubiquitination Chorion Development Positive Regulation Of RNA Metabolic Process
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