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TCEA2 and MCM2
Number of citations of the paper that reports this interaction (PMID
12392551
)
11
Data Source:
BioGRID
(pull down)
TCEA2
MCM2
Gene Name
transcription elongation factor A (SII), 2
minichromosome maintenance complex component 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Centrosome
Transcription Elongation Factor Complex
Chromatin
Nucleus
Nucleoplasm
Nuclear Origin Of Replication Recognition Complex
Cytoplasm
Microtubule Cytoskeleton
MCM Complex
Molecular Function
DNA Binding
Protein Binding
Zinc Ion Binding
DNA Binding
DNA Helicase Activity
DNA Replication Origin Binding
Protein Binding
ATP Binding
Histone Binding
Metal Ion Binding
Biological Process
DNA-templated Transcription, Elongation
Regulation Of DNA-templated Transcription, Elongation
Positive Regulation Of Transcription From RNA Polymerase II Promoter
G1/S Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
DNA Replication
DNA Unwinding Involved In DNA Replication
DNA Replication Initiation
DNA Strand Elongation Involved In DNA Replication
Nucleosome Assembly
Cell Cycle
Cellular Response To Interleukin-4
Pathways
Synthesis of DNA
G2/M Checkpoints
Activation of the pre-replicative complex
DNA Replication Pre-Initiation
M/G1 Transition
Regulation of DNA replication
Activation of the pre-replicative complex
Orc1 removal from chromatin
S Phase
DNA strand elongation
Cell Cycle, Mitotic
Assembly of the pre-replicative complex
Orc1 removal from chromatin
G1/S Transition
Activation of ATR in response to replication stress
Cell Cycle Checkpoints
Removal of licensing factors from origins
Mitotic G1-G1/S phases
Switching of origins to a post-replicative state
Unwinding of DNA
Drugs
Diseases
GWAS
Protein-Protein Interactions
47 interactors:
ADAMTSL4
AKT1S1
ALAS1
APP
BRCA1
CAMKV
CCDC136
CCSER2
CDK11B
CENPT
CEP44
DAB1
DCAF10
DHRS2
DNAJB9
EAF2
EXOSC8
FAM9B
FBF1
GOLGA2
GPKOW
GRIPAP1
GTF2B
KIAA1958
KRT40
KRTAP10-7
KRTAP5-9
LZTS2
MAGEA11
MARK3
MCM2
MEOX2
MID2
MKRN3
RPA1
SH3GL2
TAX1BP1
TAX1BP3
TCF4
TFCP2
THAP1
TNIP1
TRAF2
TRIM27
TRIM54
TSGA10
WDR47
47 interactors:
AKAP8
APP
ATM
ATR
CCNB2
CCNC
CDC6
CDC7
CDK2
CDK4
CDK6
CDKN2A
CPSF1
CSNK2A1
DBF4
ELL
GNB5
GTF2B
GTF2H1
HIST3H3
KAT7
MCM10
MCM3
MCM4
MCM5
MCM6
MCM7
MCPH1
MOB4
MPP3
ORC1
ORC2
ORC4
ORC5
ORC6
P2RX4
PHC2
PLK1
RAD52
RPA1
RPA2
RPA3
RPS4X
TBP
TCEA2
TERF1
TERF2IP
Entrez ID
6919
4171
HPRD ID
16069
00303
Ensembl ID
ENSG00000171703
ENSG00000073111
Uniprot IDs
Q15560
Q6IB64
Q86VL0
P49736
PDB IDs
2LW4
Enriched GO Terms of Interacting Partners
?
Regulation Of Protein Binding
Protein-DNA Complex Assembly
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Cell Death
Death
Cell Cycle
Negative Regulation Of Viral Process
Protein Ubiquitination
Negative Regulation Of Viral Release From Host Cell
Negative Regulation Of Signal Transduction
Protein Modification By Small Protein Conjugation
Cellular Macromolecular Complex Assembly
Negative Regulation Of Signaling
Negative Regulation Of Viral Transcription
Regulation Of Viral Release From Host Cell
Cellular Component Assembly
Regulation Of Binding
Apoptotic Process
DNA Strand Elongation Involved In DNA Replication
Regulation Of Phosphorylation
Programmed Cell Death
Regulation Of Protein Kinase Activity
Regulation Of Cellular Response To Heat
DNA Strand Elongation
Mitotic Cell Cycle
Cell Cycle Process
Protein K63-linked Ubiquitination
Protein Trimerization
Regulation Of Kinase Activity
Positive Regulation Of Histone H4-K20 Methylation
Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration
Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade
Positive Regulation Of Histone H4-K16 Acetylation
Innate Immune Response
Immune System Process
Protein Autoubiquitination
Regulation Of Viral Process
Regulation Of Phosphorus Metabolic Process
Response To Stress
Cellular Response To Stress
Protein Polyubiquitination
Cerebellum Structural Organization
Negative Regulation Of Interleukin-2 Secretion
Synaptic Growth At Neuromuscular Junction
Positive Regulation Of Histone H3-K9 Acetylation
Catenin Import Into Nucleus
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition
Negative Regulation Of Wnt Signaling Pathway
Regulation Of Signal Transduction
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
G1/S Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle Process
DNA Replication
Mitotic Cell Cycle
Cell Cycle Process
DNA Metabolic Process
Cell Cycle
DNA-dependent DNA Replication
DNA Replication Initiation
Nucleobase-containing Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Nitrogen Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
DNA Strand Elongation Involved In DNA Replication
DNA Strand Elongation
Biosynthetic Process
Chromosome Organization
Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of Cell Cycle
Regulation Of Cell Cycle Phase Transition
Regulation Of Mitotic Cell Cycle
Cellular Metabolic Process
DNA Recombinase Assembly
Telomere Maintenance
Regulation Of Cell Cycle Process
Double-strand Break Repair Via Homologous Recombination
Recombinational Repair
Positive Regulation Of Cell Cycle Process
Regulation Of Cellular Response To Heat
Positive Regulation Of Cell Cycle
Telomere Maintenance Via Telomere Lengthening
Cell Division
Cell Cycle Checkpoint
Double-strand Break Repair
Organelle Organization
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Regulation Of Cell Cycle G2/M Phase Transition
Cellular Response To DNA Damage Stimulus
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Nucleotide-excision Repair, DNA Damage Removal
Regulation Of Mitotic Metaphase/anaphase Transition
Positive Regulation Of Mitotic Cell Cycle Phase Transition
Positive Regulation Of Cell Cycle Phase Transition
Positive Regulation Of Mitotic Cell Cycle
Negative Regulation Of Cell Cycle
Tagcloud
?
1alpha
1beta
bcl2
carcinogenic
ccr2
cervices
e2
epithelia
hek293
hpv16
ikappabalpha
inflammation
intact
integration
isomerase
mediators
peptidyl
pin1
potentiated
prolyl
rela
sdf
ser727
squamous
stat3
stromal
supports
survivin
transformed
Tagcloud (Difference)
?
1alpha
1beta
bcl2
carcinogenic
ccr2
cervices
e2
epithelia
hek293
hpv16
ikappabalpha
inflammation
intact
integration
isomerase
mediators
peptidyl
pin1
potentiated
prolyl
rela
sdf
ser727
squamous
stat3
stromal
supports
survivin
transformed
Tagcloud (Intersection)
?