MCRS1 and FXR2

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MCRS1	FXR2
Gene Name		microspherule protein 1	fragile X mental retardation, autosomal homolog 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleoplasm Nucleolus Cytoplasm Actin Cytoskeleton Cell Junction Ino80 Complex MLL1 Complex	Nucleus Cytoplasm Polysome Membrane Cytosolic Large Ribosomal Subunit Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Histone Acetyltransferase Activity (H4-K5 Specific) Histone Acetyltransferase Activity (H4-K8 Specific) Histone Acetyltransferase Activity (H4-K16 Specific)	RNA Binding MRNA Binding Protein Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process	DNA Repair DNA Recombination Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cellular Protein Modification Process Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K16 Acetylation	Negative Regulation Of Translation
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS			IgM levels ( 23118916) Sex hormone-binding globulin levels ( 22675492)
Protein-Protein Interactions		30 interactors: BLM CCDC53 CCDC85B CEP44 DAXX DVL2 FXR2 GCC1 GPBP1 IKZF1 KDM1A KIAA1958 KXD1 LIG4 LSM6 MAGEA11 MED4 NOP2 PBX2 PHC2 PINX1 PRMT5 RALYL SUV39H1 TERT TRIM37 UPF3B USHBP1 WBP11 ZBTB22	90 interactors: AMOTL2 AP1M1 AP2M1 ARL6IP1 BAZ2B BRCA1 BYSL C10orf62 C1orf35 CALCOCO2 CAMK2D CBS CCDC33 CCDC85B CDKL3 CEP44 CEP55 COIL CYFIP1 CYFIP2 DPPA2 EWSR1 FAM90A1 FBP1 FMR1 FTH1 FXR1 GKAP1 HMBOX1 HNRNPC KCNRG KCTD4 KIAA1217 KIF1A KRT20 KXD1 LASP1 LCMT1 LCP2 LDOC1 MBIP MCRS1 MEAF6 MFAP1 MIA3 MORF4L1 MRPL43 NCK2 NDN NECAB2 NIF3L1 NME1 NONO NT5C2 PAF1 PAICS PCBD1 PIM1 POM121 PRAM1 PSME3 PTS RABAC1 RALYL RBBP8 RBMX RBPMS RPIA RTN3 RTN4 SCEL SNAP23 SRPK2 SSSCA1 SYT6 SYTL4 TBC1D22B THAP1 TNNT1 TRAF2 TRIM23 TRIM29 TRIM37 TSC22D4 YES1 ZBTB22 ZBTB8A ZMAT2 ZNF451 ZSCAN1
Entrez ID		10445	9513
HPRD ID		11298	05629
Ensembl ID		ENSG00000187778	ENSG00000129245
Uniprot IDs		Q7Z372 Q96EZ8	P51116
PDB IDs			3H8Z
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Chromosome Organization Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process RNA Biosynthetic Process Gene Expression Negative Regulation Of Biosynthetic Process Transcription, DNA-templated Chromatin Modification Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Chromatin Organization RRNA Processing RRNA Metabolic Process Positive Regulation Of Gene Expression Ribonucleoprotein Complex Biogenesis Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Ribosome Biogenesis Telomere Maintenance Via Telomerase Telomere Maintenance Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Transcription, DNA-templated NcRNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Metabolic Process DNA Replication RNA-dependent DNA Replication RNA Processing Positive Regulation Of Transcription, DNA-templated Leukocyte Differentiation RNA Splicing DNA Strand Elongation Telomere Maintenance Via Telomere Lengthening Response To X-ray T Cell Differentiation Histone Modification	RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Metabolic Process Heterocycle Metabolic Process Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Biosynthetic Process Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Cellular Process Cellular Process Negative Regulation Of Centriole Replication Macromolecule Biosynthetic Process Developmental Cell Growth Protein Homooligomerization Tetrahydrobiopterin Biosynthetic Process Pteridine-containing Compound Biosynthetic Process Endoplasmic Reticulum Tubular Network Organization Cellular Macromolecule Biosynthetic Process Protein Autoubiquitination Protein Oligomerization Histone Acetylation Vesicle-mediated Transport Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Regulation Of Centriole Replication Histone H4 Acetylation Internal Protein Amino Acid Acetylation Pteridine-containing Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Histone H4-K5 Acetylation Histone H4-K8 Acetylation Negative Regulation Of Gene Expression Protein Acetylation DNA Recombination Histone H2A Acetylation Cellular Metabolic Process Neuron Projection Extension Negative Regulation Of Centrosome Duplication Cell Growth Negative Regulation Of Cell Growth Histone Modification
Tagcloud ?		acetylates akhtar buscaino duncan gebhardt h4k16 hcf1 holz ino80 mendjan mof moz msl mueller myst myst1 nsl nucleosomal relaxed sas2 sas3 saumweber schelder stunnenberg taipale vermeulen wdr5 wilm ybf2	17p13 adipocytes array cgh disability duplication dysmorphic encodes encompassing facial fingers fissures glut4 hyperpigmentation intellectual mandible nlgn2 nostrils obesity p13 palpebral proposita recognizable referred seizures slc2a4 slender tp53 upturned
Tagcloud (Difference) ?		acetylates akhtar buscaino duncan gebhardt h4k16 hcf1 holz ino80 mendjan mof moz msl mueller myst myst1 nsl nucleosomal relaxed sas2 sas3 saumweber schelder stunnenberg taipale vermeulen wdr5 wilm ybf2	17p13 adipocytes array cgh disability duplication dysmorphic encodes encompassing facial fingers fissures glut4 hyperpigmentation intellectual mandible nlgn2 nostrils obesity p13 palpebral proposita recognizable referred seizures slc2a4 slender tp53 upturned
Tagcloud (Intersection) ?