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MCRS1 and GCC1
Number of citations of the paper that reports this interaction (PMID
19060904
)
157
Data Source:
BioGRID
(two hybrid)
MCRS1
GCC1
Gene Name
microspherule protein 1
GRIP and coiled-coil domain containing 1
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Histone Acetyltransferase Complex
Nucleoplasm
Nucleolus
Cytoplasm
Actin Cytoskeleton
Cell Junction
Ino80 Complex
MLL1 Complex
Golgi Membrane
Cytoplasm
Golgi Apparatus
Plasma Membrane
Molecular Function
Protein Binding
Histone Acetyltransferase Activity (H4-K5 Specific)
Histone Acetyltransferase Activity (H4-K8 Specific)
Histone Acetyltransferase Activity (H4-K16 Specific)
Protein Binding
Biological Process
DNA Repair
DNA Recombination
Chromatin Organization
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Cellular Protein Modification Process
Histone H4-K5 Acetylation
Histone H4-K8 Acetylation
Histone H4-K16 Acetylation
Protein Targeting To Golgi
Pathways
Chromatin modifying enzymes
Chromatin organization
HATs acetylate histones
Drugs
Diseases
GWAS
Type 2 diabetes (
22158537
)
Protein-Protein Interactions
30 interactors:
BLM
CCDC53
CCDC85B
CEP44
DAXX
DVL2
FXR2
GCC1
GPBP1
IKZF1
KDM1A
KIAA1958
KXD1
LIG4
LSM6
MAGEA11
MED4
NOP2
PBX2
PHC2
PINX1
PRMT5
RALYL
SUV39H1
TERT
TRIM37
UPF3B
USHBP1
WBP11
ZBTB22
36 interactors:
ABI2
AMOTL2
APP
ARL1
ATF4
ATN1
BIRC2
BRCA1
C1orf94
CCDC85B
CEP57
CEP70
COIL
CPSF7
DNAJA3
FBF1
GLI1
GOLGA2
GTF2I
IKBKG
ITSN1
KIAA0753
KIAA1217
LZTS2
MCRS1
NAB2
NAV1
NECAB2
NINL
OIP5
PAK7
SMARCD1
TFIP11
TRIM29
USHBP1
ZNF276
Entrez ID
10445
79571
HPRD ID
11298
07599
Ensembl ID
ENSG00000187778
ENSG00000179562
Uniprot IDs
Q7Z372
Q96EZ8
A4D0Z4
Q96CN9
PDB IDs
Enriched GO Terms of Interacting Partners
?
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Chromosome Organization
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
RNA Biosynthetic Process
Gene Expression
Negative Regulation Of Biosynthetic Process
Transcription, DNA-templated
Chromatin Modification
Biosynthetic Process
Regulation Of Gene Expression
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Gene Expression
Chromatin Organization
RRNA Processing
RRNA Metabolic Process
Positive Regulation Of Gene Expression
Ribonucleoprotein Complex Biogenesis
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of RNA Metabolic Process
Regulation Of Metabolic Process
Ribosome Biogenesis
Telomere Maintenance Via Telomerase
Telomere Maintenance
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Regulation Of Transcription, DNA-templated
NcRNA Metabolic Process
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Positive Regulation Of Cellular Biosynthetic Process
Cellular Metabolic Process
DNA Replication
RNA-dependent DNA Replication
RNA Processing
Positive Regulation Of Transcription, DNA-templated
Leukocyte Differentiation
RNA Splicing
DNA Strand Elongation
Telomere Maintenance Via Telomere Lengthening
Response To X-ray
T Cell Differentiation
Histone Modification
Apoptotic Process
Programmed Cell Death
Cell Death
Death
Organelle Organization
Transcription, DNA-templated
RNA Metabolic Process
Regulation Of Transcription, DNA-templated
RNA Biosynthetic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Gene Expression
Nucleobase-containing Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Intracellular Signal Transduction
Macromolecule Biosynthetic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Gene Expression
Anatomical Structure Development
Developmental Process
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Toxin Metabolic Process
Negative Regulation Of Cell Death
Mitotic Cell Cycle
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Transcription From RNA Polymerase III Promoter
Nitrogen Compound Metabolic Process
G2/M Transition Of Mitotic Cell Cycle
Positive Regulation Of Protein Ubiquitination
Cell Communication
Positive Regulation Vascular Endothelial Growth Factor Production
Signal Transduction
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
System Development
Multicellular Organismal Development
Cellular Process
NIK/NF-kappaB Signaling
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Biosynthetic Process
Cell Cycle
Positive Regulation Of Histone H4-K20 Methylation
Spliceosomal Complex Disassembly
Positive Regulation Of Histone H4-K16 Acetylation
Positive Regulation Of Protein K63-linked Ubiquitination
Positive Regulation Of Protein Monoubiquitination
Positive Regulation Of Protein K48-linked Ubiquitination
Tagcloud
?
acetylates
akhtar
buscaino
duncan
gebhardt
h4k16
hcf1
holz
ino80
mendjan
mof
moz
msl
mueller
myst
myst1
nsl
nucleosomal
relaxed
sas2
sas3
saumweber
schelder
stunnenberg
taipale
vermeulen
wdr5
wilm
ybf2
Tagcloud (Difference)
?
acetylates
akhtar
buscaino
duncan
gebhardt
h4k16
hcf1
holz
ino80
mendjan
mof
moz
msl
mueller
myst
myst1
nsl
nucleosomal
relaxed
sas2
sas3
saumweber
schelder
stunnenberg
taipale
vermeulen
wdr5
wilm
ybf2
Tagcloud (Intersection)
?