RBM14 and NDEL1

Number of citations of the paper that reports this interaction (PubMedID 30217970)
38

Data Source:
BioGRID (two hybrid)

		RBM14	NDEL1
Description		RNA binding motif protein 14	nudE neurodevelopment protein 1 like 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Regulator Complex Nucleolus Cytoplasm Nuclear Speck Ribonucleoprotein Complex	Chromosome, Centromeric Region Kinetochore Chromosome Cytoplasm Centrosome Microtubule Organizing Center Spindle Cytosol Cytoskeleton Kinesin Complex Microtubule Microtubule Associated Complex Synaptic Vesicle Axon Cell Leading Edge Axon Hillock Neurofilament Cytoskeleton Axon Cytoplasm
	Molecular Function	Nucleic Acid Binding Transcription Coactivator Activity RNA Binding MRNA Binding Protein Binding Splicing Factor Binding	Protein Binding Microtubule Binding Identical Protein Binding Alpha-tubulin Binding Beta-tubulin Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Activation Of Innate Immune Response Immune System Process Apoptotic Process Gastrulation Response To Hormone Gene Expression Innate Immune Response Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Centriole Replication Centriole Assembly Regulation Of Response To DNA Integrity Checkpoint Signaling	Establishment Of Mitotic Spindle Orientation Microtubule Cytoskeleton Organization Neuron Migration Inner Cell Mass Cell Proliferation Microtubule Nucleation Chromosome Segregation Mitotic Centrosome Separation Nervous System Development Retrograde Axonal Transport Insulin Receptor Signaling Pathway Regulation Of Neuron Projection Development Cell Migration Cerebral Cortex Radially Oriented Cell Migration Central Nervous System Neuron Axonogenesis Cell Differentiation Lysosome Localization Regulation Of Intracellular Protein Transport Positive Regulation Of GTPase Activity Vesicle Transport Along Microtubule Chromosome Localization Centrosome Localization Neurofilament Cytoskeleton Organization Radial Glia-guided Pyramidal Neuron Migration Positive Regulation Of Ruffle Assembly Neuron Projection Extension
Pathways		RUNX2 regulates bone development	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)
Interacting Genes		118 interacting genes: AKAP9 ATN1 CASK CEBPA CEP55 CFTR CRLF3 CTBP1 DDX17 DDX6 DMRTB1 DYNLT1 EP300 FMR1 FXR2 HOMER3 ITCH KHDRBS2 KIFAP3 KLC4 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NCOA6 NDEL1 NEDD4 NFKBID NR3C1 PARD6G PARP1 PCBP1 PRKCI QKI RBM10 RBM5 RPA2 RUNX1 RUNX2 SLAIN1 SS18 SYT1 TARBP2 TRIM55 TRIM63 UBE2I UFSP1 XRCC5 YAP1 YWHAE	85 interacting genes: ABI3 ACTB AIMP2 AKAP9 ANK2 APP BMI1 BORCS6 BRK1 CASK CCDC88A CCSER1 CDK5 CENPF CEP170 CEP55 CEP63 CWF19L2 DISC1 DIXDC1 DTNB DYNC1H1 DYNLL1 FXR2 GOLGA2 IMMT KALRN KIF19 KIF2C KIF5A KIFC3 KLC4 LUC7L2 MAGEA11 MBIP MED11 MIS18A MLLT10 MRC2 MTUS2 MYO5A NDC80 PAFAH1B1 PARD6G PARVG PICK1 PKP2 PRC1 RBM10 RBM14 RBM5 RPA2 SLAIN1 SNAPC5 SNX6 SYNE1 TACC3 TRAF3IP3 TUBB USP2 XPA YWHAE YWHAG ZC2HC1C ZNF10 ZNF12 ZNF17 ZNF180 ZNF197 ZNF211 ZNF230 ZNF250 ZNF260 ZNF264 ZNF3 ZNF35 ZNF417 ZNF490 ZNF544 ZNF572 ZNF599 ZNF662 ZNF707 ZNF844 ZNF91
Entrez ID		10432	81565
HPRD ID		11485	06340
Ensembl ID		ENSG00000239306	ENSG00000166579
Uniprot IDs		A0A0S2Z4Z0 A0A0S2Z567 A0A0S2Z5V2 Q96PK6	A6NIZ0 Q9GZM8
PDB IDs		2DNP	2V66
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Regulation Of Gene Expression Extracellular Vesicle Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Translation Regulation Of Macromolecule Metabolic Process MRNA Destabilization Regulation Of Metabolic Process Positive Regulation Of MRNA Catabolic Process RNA Destabilization Negative Regulation Of Cytokine Production Positive Regulation Of MRNA Metabolic Process Regulation Of MRNA Stability Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Regulation Of Translation Regulation Of RNA Stability Regulation Of Angiogenesis Negative Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Vasculature Development Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Developmental Process Regulation Of MRNA Metabolic Process Negative Regulation Of Cell Migration Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Regulation Of Developmental Process Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Protein Metabolic Process Regulation Of Multicellular Organismal Development Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Signal Transduction Regulation Of Multicellular Organismal Process Negative Regulation Of Signaling Negative Regulation Of Cell Communication Negative Regulation Of Blood Vessel Endothelial Cell Migration	Microtubule-based Process Cytoskeleton Microtubule Cell Division Kinesin Complex Microtubule Binding Microtubule Cytoskeleton Organization Cytoskeleton Organization Centrosome Nucleus Regulation Of Transcription By RNA Polymerase II Zinc Ion Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Identical Protein Binding Regulation Of RNA Biosynthetic Process DNA Binding Cytoskeleton-dependent Intracellular Transport Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Maintenance Of Location In Cell Organelle Organization Kinesin Binding Maintenance Of Location Regulation Of Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Cytoplasmic Microtubule Organization Organelle Localization Acetylcholine Receptor Activator Activity Microtubule-based Movement Regulation Of Heart Rate By Cardiac Conduction Metal Ion Binding Establishment Of Organelle Localization Regulation Of Cell Cycle Microtubule Organizing Center Organization Central Region Of Growth Cone Protein Binding Cardiac Conduction Protein Kinase C Binding Retrograde Axonal Transport Presynapse Kinetochore Supramolecular Fiber Organization Maintenance Of Protein Location In Cell Spindle Organization Regulation Of Microtubule Cytoskeleton Organization Cytoplasmic Microtubule Microtubule Motor Activity
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