RBM14 and CRLF3

Number of citations of the paper that reports this interaction (PubMedID 26871637)
43

Data Source:
BioGRID (two hybrid)

		RBM14	CRLF3
Description		RNA binding motif protein 14	cytokine receptor like factor 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Regulator Complex Nucleolus Cytoplasm Nuclear Speck Ribonucleoprotein Complex	Nucleus Cytoplasm Cytosol Plasma Membrane
	Molecular Function	Nucleic Acid Binding Transcription Coactivator Activity RNA Binding MRNA Binding Protein Binding Splicing Factor Binding	DNA Binding Protein Binding Identical Protein Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Activation Of Innate Immune Response Immune System Process Apoptotic Process Gastrulation Response To Hormone Gene Expression Innate Immune Response Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Centriole Replication Centriole Assembly Regulation Of Response To DNA Integrity Checkpoint Signaling	Negative Regulation Of Cell Growth Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		RUNX2 regulates bone development
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)	Birth weight ( 27680694) Chronic obstructive pulmonary disease ( 30804561) Cutaneous leishmaniasis ( 32830257) Height ( 18391951 28552196) Hip circumference adjusted for BMI ( 34021172) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 29403010) Platelet distribution width ( 32888494) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		118 interacting genes: AKAP9 ATN1 CASK CEBPA CEP55 CFTR CRLF3 CTBP1 DDX17 DDX6 DMRTB1 DYNLT1 EP300 FMR1 FXR2 HOMER3 ITCH KHDRBS2 KIFAP3 KLC4 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NCOA6 NDEL1 NEDD4 NFKBID NR3C1 PARD6G PARP1 PCBP1 PRKCI QKI RBM10 RBM5 RPA2 RUNX1 RUNX2 SLAIN1 SS18 SYT1 TARBP2 TRIM55 TRIM63 UBE2I UFSP1 XRCC5 YAP1 YWHAE	10 interacting genes: APPL2 DDIT4L KCTD21 KDM1A L3MBTL3 LGALS14 MYOZ3 RBM14 VPS25 ZFP1
Entrez ID		10432	51379
HPRD ID		11485	16757
Ensembl ID		ENSG00000239306	ENSG00000176390
Uniprot IDs		A0A0S2Z4Z0 A0A0S2Z567 A0A0S2Z5V2 Q96PK6	Q8IUI8
PDB IDs		2DNP
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Regulation Of Gene Expression Extracellular Vesicle Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Translation Regulation Of Macromolecule Metabolic Process MRNA Destabilization Regulation Of Metabolic Process Positive Regulation Of MRNA Catabolic Process RNA Destabilization Negative Regulation Of Cytokine Production Positive Regulation Of MRNA Metabolic Process Regulation Of MRNA Stability Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Regulation Of Translation Regulation Of RNA Stability Regulation Of Angiogenesis Negative Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Vasculature Development Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Developmental Process Regulation Of MRNA Metabolic Process Negative Regulation Of Cell Migration Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Regulation Of Developmental Process Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Protein Metabolic Process Regulation Of Multicellular Organismal Development Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Signal Transduction Regulation Of Multicellular Organismal Process Negative Regulation Of Signaling Negative Regulation Of Cell Communication Negative Regulation Of Blood Vessel Endothelial Cell Migration	Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Regulation Of Chromatin Organization
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