RBM14 and RUNX2

Number of citations of the paper that reports this interaction (PMID 19585539)
5

Data Source:
BioGRID (imaging technique, affinity chromatography technology, pull down)

		RBM14	RUNX2
Gene Name		RNA binding motif protein 14	runt-related transcription factor 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Transcription Factor Complex Nucleolus Mediator Complex Ribonucleoprotein Complex	Nuclear Chromatin Nucleoplasm Transcription Factor Complex Cytoplasm
	Molecular Function	Nucleotide Binding RNA Polymerase II Transcription Cofactor Activity RNA Binding Protein Binding Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Protein Binding, Bridging Poly(A) RNA Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding ATP Binding Protein Domain Specific Binding BHLH Transcription Factor Binding Repressing Transcription Factor Binding
	Biological Process	DNA Replication DNA Repair DNA Recombination Transcription From RNA Polymerase II Promoter Response To Hormone Histone Deacetylation Intracellular Estrogen Receptor Signaling Pathway Glucocorticoid Receptor Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter	Ossification Osteoblast Differentiation Endochondral Ossification Osteoblast Fate Commitment Chondrocyte Development Osteoblast Development Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Cell Proliferation Gene Expression T Cell Differentiation BMP Signaling Pathway Positive Regulation Of Chondrocyte Differentiation Embryonic Forelimb Morphogenesis Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Odontogenesis Of Dentin-containing Tooth Regulation Of Odontogenesis Of Dentin-containing Tooth Positive Regulation Of Osteoblast Differentiation Negative Regulation Of Smoothened Signaling Pathway Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Cell Maturation Embryonic Cranial Skeleton Morphogenesis Stem Cell Differentiation Cellular Response To BMP Stimulus Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus
Pathways			Generic Transcription Pathway YAP1- and WWTR1 (TAZ)-stimulated gene expression
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)	Height ( 18391951) Periodontal microbiota ( 22699663)
Protein-Protein Interactions		11 interactors: EP300 NCOA6 NR3C1 PARP1 QKI RUNX1 RUNX2 SS18 SYT1 TARBP2 XRCC5	36 interactors: ALYREF AR AXIN1 CBFB CCNB1 CDK1 CEBPB DVL2 EP300 ETS1 FHL2 FOS HDAC3 HDAC4 HDAC6 HIF1A HIVEP3 JUN KAT6B LEF1 MAP3K4 MSX2 PRKCD RB1 RBM14 SMAD2 SMAD3 SMAD6 SMURF2 SOX9 STUB1 TAF1A UBTF XRCC5 XRCC6 YAP1
Entrez ID		10432	860
HPRD ID		11485	02566
Ensembl ID			ENSG00000124813
Uniprot IDs		Q96PK6	F8W8U5 Q13950 Q32MY8
PDB IDs		2DNP
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Positive Regulation Of Gene Expression Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Transcription, DNA-templated Heterocycle Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Response To Organic Substance DNA-templated Transcription, Initiation Glucocorticoid Receptor Signaling Pathway Nitrogen Compound Metabolic Process Cellular Response To Organic Substance Hemopoiesis Regulation Of Transcription, DNA-templated Immune System Development Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Biosynthetic Process Anatomical Structure Development Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Developmental Process Regulation Of Metabolic Process System Development Organ Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus Immune System Process Myeloid Cell Differentiation Negative Regulation Of Gene Expression Response To Stimulus Multicellular Organismal Development Cell Differentiation Cellular Response To Stimulus Chordate Embryonic Development Anatomical Structure Morphogenesis Stem Cell Differentiation	Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Gene Expression Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process RNA Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Biosynthetic Process Transcription From RNA Polymerase II Promoter Response To Organic Substance Negative Regulation Of Transcription, DNA-templated Organ Development Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Organic Substance Cellular Metabolic Process Cellular Response To Stimulus Tissue Development Cellular Response To Stress System Development Regulation Of Cell Differentiation Response To Growth Factor Developmental Process Heart Development Positive Regulation Of Cell Differentiation Cardiovascular System Development Cell Differentiation Negative Regulation Of Signal Transduction
Tagcloud ?		aggregating conjugation detergent dialkylated eif4a1 g3bp glycine granular hek hnrnps identities immunocytochemistry insoluble isotope nono oligomerization pabpc1 paraspeckle proteinopathies psf ptm quantitate rgg rrm s6 silac tdp tls ubiquitination	1q22 aml correlative cytogenetic decitabine demethylating elucidate epigenetics frequent haematological hypermethylation inactivation inv leukaemia leukaemias lymphocytic malignancies methylated mostly myelodysplatic p13 promoters re relapse runx1 runx3 syndromes unmethylated
Tagcloud (Difference) ?		aggregating conjugation detergent dialkylated eif4a1 g3bp glycine granular hek hnrnps identities immunocytochemistry insoluble isotope nono oligomerization pabpc1 paraspeckle proteinopathies psf ptm quantitate rgg rrm s6 silac tdp tls ubiquitination	1q22 aml correlative cytogenetic decitabine demethylating elucidate epigenetics frequent haematological hypermethylation inactivation inv leukaemia leukaemias lymphocytic malignancies methylated mostly myelodysplatic p13 promoters re relapse runx1 runx3 syndromes unmethylated
Tagcloud (Intersection) ?