AKAP8 and CCND3

Number of citations of the paper that reports this interaction (PMID 14641107)
2

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		AKAP8	CCND3
Gene Name		A kinase (PRKA) anchor protein 8	cyclin D3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Condensed Chromosome Female Pronucleus Nucleus Nucleoplasm Mitochondrion Golgi Apparatus Membrane Nuclear Matrix	Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleus Cytoplasm Membrane
	Molecular Function	Double-stranded DNA Binding Zinc Ion Binding Protein Kinase A Regulatory Subunit Binding Poly(A) RNA Binding	Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding Protein Kinase Binding
	Biological Process	Mitotic Nuclear Division Mitotic Chromosome Condensation Signal Transduction	Positive Regulation Of Protein Phosphorylation Cell Cycle Signal Transduction T Cell Proliferation Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cell Division
Pathways			Cyclin D associated events in G1 Transcriptional regulation of white adipocyte differentiation G1 Phase Mitotic G1-G1/S phases Cell Cycle, Mitotic
Drugs
Diseases
GWAS			Hematological parameters ( 19820697) Mean corpuscular hemoglobin ( 20139978 19862010) Mean corpuscular volume ( 23263863 20139978 19862010) Metabolite levels (5-HIAA/ MHPG Ratio) ( 23319000) Neutrophil count ( 21507922) Red blood cell count ( 20139978) Red blood cell traits ( 23222517)
Protein-Protein Interactions		10 interactors: AMY1A CASP3 CCND1 CCND2 CCND3 CSNK2A1 DDX5 MCM2 PRKAR2A RELA	38 interactors: AKAP8 APP AREG ATF5 ATP5C1 CASP2 CDK11B CDK14 CDK4 CDK6 CDKN1A CDKN1B CRABP2 DMTF1 DTNBP1 EFEMP2 EIF3K ETV1 FAS GC MAF1 MAPK4 MAPK6 MCM10 MYB NCOA2 NME1 NPDC1 PCNA POLD1 POLR3GL RARA RB1 RBL2 RUNX1 SIL1 TFIP11 VDR
Entrez ID		10270	896
HPRD ID		05258	00452
Ensembl ID		ENSG00000105127	ENSG00000112576
Uniprot IDs		M0QYL4 O43823	P30281 Q5T8J1
PDB IDs			3G33
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Protein Metabolic Process Regulation Of Phosphorylation Regulation Of Protein Metabolic Process Regulation Of Protein Kinase Activity Positive Regulation Of Metabolic Process Regulation Of Kinase Activity Regulation Of Phosphorus Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Response To UV Positive Regulation Of Protein Kinase Activity Positive Regulation Of Kinase Activity Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Transferase Activity Cellular Response To Growth Factor Stimulus Negative Regulation Of Cellular Metabolic Process Response To Growth Factor Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Cell Cycle Regulation Of Catalytic Activity Positive Regulation Of Protein Phosphorylation Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Cell Cycle Positive Regulation Of Catalytic Activity Regulation Of Metabolic Process Positive Regulation Of Phosphorylation Response To Light Stimulus Negative Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Acetaldehyde Metabolic Process Cellular Response To Organic Substance Cell Division Response To Radiation Negative Regulation Of Cell Cycle Positive Regulation Of Schwann Cell Differentiation Response To Vitamin Cellular Response To Stimulus Negative Regulation Of Protein Catabolic Process Response To Drug Re-entry Into Mitotic Cell Cycle Regulation Of Schwann Cell Differentiation Response To Tumor Necrosis Factor Negative Regulation Of Protein Serine/threonine Kinase Activity Signal Transduction Response To Cobalamin	Mitotic Cell Cycle Cell Cycle G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Cell Cycle Process Cell Cycle Process Cellular Metabolic Process Organ Development Regulation Of Cell Cycle Regulation Of Gene Expression Positive Regulation Of Cell Cycle Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process System Development Response To Steroid Hormone Positive Regulation Of Metabolic Process Multicellular Organismal Development Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Metabolic Process Positive Regulation Of Cell Cycle Process Anatomical Structure Development Regulation Of Cell Cycle Phase Transition Positive Regulation Of Gene Expression Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Process Response To Lipid Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Metabolic Process Regulation Of Myeloid Cell Differentiation Response To Stimulus Developmental Process Response To Hormone Positive Regulation Of Macromolecule Biosynthetic Process Response To Hyperoxia Cellular Response To Stimulus Intracellular Receptor Signaling Pathway Regulation Of Cell Cycle Arrest Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Process Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Kinase Activity Response To Abiotic Stimulus Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Mitotic Cell Cycle
Tagcloud ?			abi1 atlas bitbucket ctnnd1 doi driver drivers dx fbln2 figshare hindered http https identifies implies isoform ktsp m9 mitf myh11 org pparg prdm1 ralgds regulatorygenomicsupf signatures splicing switches transcript
Tagcloud (Difference) ?			abi1 atlas bitbucket ctnnd1 doi driver drivers dx fbln2 figshare hindered http https identifies implies isoform ktsp m9 mitf myh11 org pparg prdm1 ralgds regulatorygenomicsupf signatures splicing switches transcript
Tagcloud (Intersection) ?