CCND3 and MAPK4

Number of citations of the paper that reports this interaction (PMID 16360641)
4

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		CCND3	MAPK4
Gene Name		cyclin D3	mitogen-activated protein kinase 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleus Cytoplasm Membrane	Nucleus Cytoplasm
	Molecular Function	Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding Protein Kinase Binding	MAP Kinase Activity Protein Binding ATP Binding Protein Kinase Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	Positive Regulation Of Protein Phosphorylation Cell Cycle Signal Transduction T Cell Proliferation Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cell Division	MAPK Cascade Protein Phosphorylation Cell Cycle
Pathways		Cyclin D associated events in G1 Transcriptional regulation of white adipocyte differentiation G1 Phase Mitotic G1-G1/S phases Cell Cycle, Mitotic
Drugs
Diseases
GWAS		Hematological parameters ( 19820697) Mean corpuscular hemoglobin ( 20139978 19862010) Mean corpuscular volume ( 23263863 20139978 19862010) Metabolite levels (5-HIAA/ MHPG Ratio) ( 23319000) Neutrophil count ( 21507922) Red blood cell count ( 20139978) Red blood cell traits ( 23222517)
Protein-Protein Interactions		38 interactors: AKAP8 APP AREG ATF5 ATP5C1 CASP2 CDK11B CDK14 CDK4 CDK6 CDKN1A CDKN1B CRABP2 DMTF1 DTNBP1 EFEMP2 EIF3K ETV1 FAS GC MAF1 MAPK4 MAPK6 MCM10 MYB NCOA2 NME1 NPDC1 PCNA POLD1 POLR3GL RARA RB1 RBL2 RUNX1 SIL1 TFIP11 VDR	7 interactors: CALML3 CCND3 CRK GAB1 GAB2 MAPKAPK5 UBC
Entrez ID		896	5596
HPRD ID		00452	01497
Ensembl ID		ENSG00000112576	ENSG00000141639
Uniprot IDs		P30281 Q5T8J1	A1A4C4 P31152 Q0VG04
PDB IDs		3G33
Enriched GO Terms of Interacting Partners?		Mitotic Cell Cycle Cell Cycle G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Cell Cycle Process Cell Cycle Process Cellular Metabolic Process Organ Development Regulation Of Cell Cycle Regulation Of Gene Expression Positive Regulation Of Cell Cycle Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process System Development Response To Steroid Hormone Positive Regulation Of Metabolic Process Multicellular Organismal Development Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Metabolic Process Positive Regulation Of Cell Cycle Process Anatomical Structure Development Regulation Of Cell Cycle Phase Transition Positive Regulation Of Gene Expression Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Process Response To Lipid Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Metabolic Process Regulation Of Myeloid Cell Differentiation Response To Stimulus Developmental Process Response To Hormone Positive Regulation Of Macromolecule Biosynthetic Process Response To Hyperoxia Cellular Response To Stimulus Intracellular Receptor Signaling Pathway Regulation Of Cell Cycle Arrest Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Process Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Kinase Activity Response To Abiotic Stimulus Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Mitotic Cell Cycle	Positive Regulation Of Protein Kinase Activity Positive Regulation Of Kinase Activity Positive Regulation Of Transferase Activity Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Fc Receptor Signaling Pathway Regulation Of Kinase Activity Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Phosphorylation Positive Regulation Of Protein Modification Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of MAPK Cascade Immune Response-regulating Signaling Pathway Positive Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Regulation Of Phosphorylation Activation Of MAPK Activity Regulation Of Phosphorus Metabolic Process Positive Regulation Of Catalytic Activity Regulation Of MAPK Cascade Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of MAP Kinase Activity Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway MAPK Cascade Innate Immune Response Positive Regulation Of Intracellular Signal Transduction Regulation Of Cellular Protein Metabolic Process Regulation Of Immune Response Enzyme Linked Receptor Protein Signaling Pathway Signal Transduction By Phosphorylation Regulation Of MAP Kinase Activity Immune System Process Regulation Of Protein Metabolic Process Regulation Of Catalytic Activity Positive Regulation Of Cellular Metabolic Process Regulation Of Signal Transduction Immune Response Signal Transduction Regulation Of Immune System Process Defense Response Signaling JNK Cascade Regulation Of Signaling Cell Communication Cellular Response To Growth Factor Stimulus
Tagcloud ?		abi1 atlas bitbucket ctnnd1 doi driver drivers dx fbln2 figshare hindered http https identifies implies isoform ktsp m9 mitf myh11 org pparg prdm1 ralgds regulatorygenomicsupf signatures splicing switches transcript
Tagcloud (Difference) ?		abi1 atlas bitbucket ctnnd1 doi driver drivers dx fbln2 figshare hindered http https identifies implies isoform ktsp m9 mitf myh11 org pparg prdm1 ralgds regulatorygenomicsupf signatures splicing switches transcript
Tagcloud (Intersection) ?