CCND3 and MAF1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CCND3	MAF1
Gene Name		cyclin D3	MAF1 homolog (S. cerevisiae)
Image
Gene Ontology Annotations	Cellular Component	Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleus Cytoplasm Membrane	Intracellular Nucleus Nucleoplasm Nucleolus Cytoplasm Centrosome Cytosol Plasma Membrane Axon Dendrite Intracellular Membrane-bounded Organelle Inhibitory Synapse
	Molecular Function	Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding Protein Kinase Binding	RNA Polymerase III Core Binding RNA Polymerase III Type 1 Promoter DNA Binding RNA Polymerase III Type 2 Promoter DNA Binding RNA Polymerase III Type 3 Promoter DNA Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation Cell Cycle Signal Transduction T Cell Proliferation Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cell Division	Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase III Promoter Transcription Factor TFIIIB Complex Assembly
Pathways		Cyclin D associated events in G1 Transcriptional regulation of white adipocyte differentiation G1 Phase Mitotic G1-G1/S phases Cell Cycle, Mitotic
Drugs
Diseases
GWAS		Hematological parameters ( 19820697) Mean corpuscular hemoglobin ( 20139978 19862010) Mean corpuscular volume ( 23263863 20139978 19862010) Metabolite levels (5-HIAA/ MHPG Ratio) ( 23319000) Neutrophil count ( 21507922) Red blood cell count ( 20139978) Red blood cell traits ( 23222517)
Protein-Protein Interactions		38 interactors: AKAP8 APP AREG ATF5 ATP5C1 CASP2 CDK11B CDK14 CDK4 CDK6 CDKN1A CDKN1B CRABP2 DMTF1 DTNBP1 EFEMP2 EIF3K ETV1 FAS GC MAF1 MAPK4 MAPK6 MCM10 MYB NCOA2 NME1 NPDC1 PCNA POLD1 POLR3GL RARA RB1 RBL2 RUNX1 SIL1 TFIP11 VDR	8 interactors: ARMCX3 CCND3 CSNK2A1 CSNK2A2 LAMTOR5 MTOR NUDT3 SUMO2
Entrez ID		896	84232
HPRD ID		00452	14345
Ensembl ID		ENSG00000112576	ENSG00000179632
Uniprot IDs		P30281 Q5T8J1	Q9H063
PDB IDs		3G33	3NR5
Enriched GO Terms of Interacting Partners?		Mitotic Cell Cycle Cell Cycle G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Cell Cycle Process Cell Cycle Process Cellular Metabolic Process Organ Development Regulation Of Cell Cycle Regulation Of Gene Expression Positive Regulation Of Cell Cycle Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process System Development Response To Steroid Hormone Positive Regulation Of Metabolic Process Multicellular Organismal Development Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Metabolic Process Positive Regulation Of Cell Cycle Process Anatomical Structure Development Regulation Of Cell Cycle Phase Transition Positive Regulation Of Gene Expression Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Process Response To Lipid Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Metabolic Process Regulation Of Myeloid Cell Differentiation Response To Stimulus Developmental Process Response To Hormone Positive Regulation Of Macromolecule Biosynthetic Process Response To Hyperoxia Cellular Response To Stimulus Intracellular Receptor Signaling Pathway Regulation Of Cell Cycle Arrest Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Process Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Kinase Activity Response To Abiotic Stimulus Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Mitotic Cell Cycle	Regulation Of Cellular Protein Metabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Metabolic Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of Proteolysis Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Proteolysis Positive Regulation Of Metabolic Process Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Processing Negative Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Catabolic Process Regulation Of Protein Processing Negative Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Cell Division Regulation Of Chromosome Segregation Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Diphosphoinositol Polyphosphate Catabolic Process Regulation Of Carbohydrate Utilization Diadenosine Polyphosphate Catabolic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Negative Regulation Of Chromosome Organization Positive Regulation Of Protein Metabolic Process Protein Phosphorylation Response To Amino Acid Negative Regulation Of Protein Catabolic Process Regulation Of Mitotic Nuclear Division Regulation Of Cell Size Negative Regulation Of Mitotic Cell Cycle Phase Transition Phosphate-containing Compound Metabolic Process Mitotic Cell Cycle Checkpoint Cellular Protein Modification Process Regulation Of Metabolic Process Response To External Stimulus Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cellular Protein Metabolic Process Phosphorylation Regulation Of Chromosome Organization Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of NFAT Protein Import Into Nucleus Negative Regulation Of Protein Metabolic Process Regulation Of Cell Cycle Phase Transition
Tagcloud ?		abi1 atlas bitbucket ctnnd1 doi driver drivers dx fbln2 figshare hindered http https identifies implies isoform ktsp m9 mitf myh11 org pparg prdm1 ralgds regulatorygenomicsupf signatures splicing switches transcript	5s affects alcohol brca1 decreases deregulation emerging enhances iii importantly leu mcf pol prb promote pten repress represses repression restoring rrna slightly suppressors tightly transformation translational trna truncated uncover
Tagcloud (Difference) ?		abi1 atlas bitbucket ctnnd1 doi driver drivers dx fbln2 figshare hindered http https identifies implies isoform ktsp m9 mitf myh11 org pparg prdm1 ralgds regulatorygenomicsupf signatures splicing switches transcript	5s affects alcohol brca1 decreases deregulation emerging enhances iii importantly leu mcf pol prb promote pten repress represses repression restoring rrna slightly suppressors tightly transformation translational trna truncated uncover
Tagcloud (Intersection) ?