STX6 and GOPC

Number of citations of the paper that reports this interaction (PMID 11384996)
17

Data Source:
HPRD (in vitro, in vivo)

		STX6	GOPC
Gene Name		syntaxin 6	golgi-associated PDZ and coiled-coil motif containing
Image
Gene Ontology Annotations	Cellular Component	Golgi Membrane Early Endosome Golgi Apparatus Trans-Golgi Network Plasma Membrane Integral Component Of Membrane Clathrin-coated Vesicle SNARE Complex Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm	Golgi Membrane Cytoplasm Golgi Apparatus Plasma Membrane Postsynaptic Density Membrane Cell Junction Trans-Golgi Network Transport Vesicle Dendrite Protein Complex Postsynaptic Membrane
	Molecular Function	SNAP Receptor Activity Protein Binding Syntaxin Binding	Small GTPase Regulator Activity Frizzled Binding Protein Binding Protein C-terminus Binding Protein Homodimerization Activity Ion Channel Binding
	Biological Process	Intracellular Protein Transport Vesicle Fusion Endosome Organization Regulation Of Protein Localization Retrograde Transport, Endosome To Golgi Golgi Vesicle Transport Golgi Ribbon Formation	ER To Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Spermatid Nucleus Differentiation Protein Transport Cytoplasmic Sequestering Of CFTR Protein Apical Protein Localization Regulation Of Catalytic Activity Protein Homooligomerization
Pathways
Drugs
Diseases
GWAS		Progressive supranuclear palsy ( 21685912)	Colorectal cancer ( 23266556)
Protein-Protein Interactions		15 interactors: EEA1 GOPC GOSR2 MARCH2 NAPB PSMA3 PTPN9 SNAP23 SNAP29 STX16 STX4 STX7 VAMP4 VPS11 VPS18	58 interactors: ABCA1 ADRB1 AKIRIN1 ASIC3 BATF BECN1 C17orf67 CCDC102B CD300C CDC42 CDKN2C CERCAM CFTR CLCN3 CSPG5 DPYD FAM90A1 FAM9B FOSL2 FZD5 FZD8 GOLGA3 GRID1 GRID2 HCK IGHG3 JUN KPNA1 LCLAT1 MORN4 MRPL1 MUM1 MYLK MYOCD NUP62 PARK7 PID1 RELA RHOQ RNF183 RNF220 RPL13AP17 RTKN SEMA4G SLC25A18 SPATA8 SSNA1 SSTR5 STARD3 STX6 TGFBR2 VIM VTN ZBTB49 ZNF564 ZNF581 ZNF587 ZSCAN1
Entrez ID		10228	57120
HPRD ID		07231	06024
Ensembl ID		ENSG00000135823	ENSG00000047932
Uniprot IDs		B4DR17 O43752	Q9HD26
PDB IDs		2NPS	2DC2 2LOB 4E34 4E35
Enriched GO Terms of Interacting Partners?		Vesicle Fusion Membrane Fusion Organelle Fusion Vesicle-mediated Transport Vesicle Organization Establishment Of Localization In Cell Membrane Organization Cellular Localization Protein Transport Establishment Of Protein Localization Intracellular Transport Protein Localization Regulation Of Protein Localization To Plasma Membrane Synaptic Vesicle Fusion To Presynaptic Membrane Transport Vesicle Docking Post-Golgi Vesicle-mediated Transport Membrane Docking Golgi Vesicle Transport Cellular Protein Localization Synaptic Vesicle Transport Intracellular Protein Transport Exocytosis Regulation Of Establishment Of Protein Localization To Plasma Membrane Organelle Organization Organelle Localization Synaptic Vesicle Exocytosis Establishment Of Vesicle Localization Golgi Ribbon Formation Vesicle Localization Secretion By Cell Regulation Of Golgi To Plasma Membrane Protein Transport Synaptic Vesicle Priming SNARE Complex Assembly Secretion Neurotransmitter Secretion Establishment Of Organelle Localization Cellular Protein Complex Assembly Regulation Of Vesicle-mediated Transport Regulation Of Neurotransmitter Levels Neurotransmitter Transport Endosomal Transport Protein Complex Assembly Vesicle Targeting Synaptic Transmission Intra-Golgi Vesicle-mediated Transport Cellular Macromolecular Complex Assembly Cellular Component Assembly Synaptic Vesicle To Endosome Fusion Cytoplasmic Sequestering Of CFTR Protein	Cellular Response To Stimulus Cellular Response To Organic Substance Response To External Stimulus Myeloid Leukocyte Differentiation Leukocyte Differentiation Response To Organic Substance Cell Surface Receptor Signaling Pathway Regulation Of Phosphorus Metabolic Process Regulation Of Cell Proliferation Regulation Of Protein Phosphorylation Response To Stimulus Cellular Process Cell Communication Positive Regulation Of Cellular Biosynthetic Process Regulation Of Binding Positive Regulation Of Transport Regulation Of Cellular Process Cell Differentiation Regulation Of Membrane Potential Myeloid Dendritic Cell Differentiation Cellular Response To Hormone Stimulus Signal Transduction Blood Vessel Morphogenesis Myeloid Dendritic Cell Activation Positive Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of DNA Binding Response To Extracellular Stimulus Negative Regulation Of Protein Phosphorylation Cell Death Death Positive Regulation Of Gene Expression T-helper 17 Cell Lineage Commitment Response To Lipid Regulation Of Phosphorylation Cellular Localization Membrane Hyperpolarization Negative Regulation Of Cell Proliferation Defense Response Regulation Of Signaling Response To Drug Positive Regulation Of DNA Binding Blood Vessel Development Response To Mechanical Stimulus Response To Stress Signaling Response To Cytokine T-helper 17 Cell Differentiation Dendritic Cell Differentiation Response To Other Organism
Tagcloud ?		alpha5beta1 alphavbeta3 boundaries c1 cho cholesterol endosome endosomes export hamster imbalance integrins interferes niemann npc1 ovary pick rab11 re recycling res restoration restores snare syntaxin tgn transferrin tuning vamp3	admissions attained clinicaltrials clinics dbp empowering empowerment equation estimating estimation generalized gov hba1c hong inpatient kong nct01935349 outpatient pep programme registration sbp september service sopc specialist t2dm utilization visits
Tagcloud (Difference) ?		alpha5beta1 alphavbeta3 boundaries c1 cho cholesterol endosome endosomes export hamster imbalance integrins interferes niemann npc1 ovary pick rab11 re recycling res restoration restores snare syntaxin tgn transferrin tuning vamp3	admissions attained clinicaltrials clinics dbp empowering empowerment equation estimating estimation generalized gov hba1c hong inpatient kong nct01935349 outpatient pep programme registration sbp september service sopc specialist t2dm utilization visits
Tagcloud (Intersection) ?