STX6 and FAM210B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		STX6	FAM210B
Description		syntaxin 6	family with sequence similarity 210 member B
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleoplasm Endosome Early Endosome Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Endomembrane System Membrane Clathrin-coated Vesicle Synaptic Vesicle Membrane Organelle Membrane SNARE Complex Vesicle Trans-Golgi Network Membrane Phagocytic Vesicle Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane	Mitochondrion Mitochondrial Outer Membrane Membrane
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Syntaxin Binding	Protein Binding
	Biological Process	Intracellular Protein Transport Vesicle Fusion Endosome Organization Protein Transport Synaptic Vesicle To Endosome Fusion Vesicle-mediated Transport Endocytic Recycling Regulation Of Protein Localization Retrograde Transport, Endosome To Golgi Golgi Vesicle Transport Vesicle Docking	Inflammatory Response Cell Differentiation Erythrocyte Differentiation Erythrocyte Maturation Skin Development Positive Regulation Of Erythrocyte Differentiation Spleen Development Cellular Response To Estradiol Stimulus Reactive Oxygen Species Metabolic Process
Pathways		Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Creutzfeldt-Jakob disease (sporadic) ( 32949544) Intralaminar thalamic nuclei volume ( 34006833) Menopause (age at onset) ( 26414677) Progressive supranuclear palsy ( 21685912 30089514) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		33 interacting genes: AQP6 ARMC8 DNAJC5 EBP EEA1 FAM210B GOLM2 GOPC LIME1 LMNA MARCHF2 MEOX2 MMGT1 MTERF2 MTIF3 NAPB PSMA3 PTPN9 SCN3B SNAP23 SNAP29 STOM STX16 STX1A STX2 STX7 TIMMDC1 TMEM14B TMEM205 TMEM86B VAMP4 VPS11 VPS18	66 interacting genes: ADGRE2 APOL2 ATP6V0B ATP6V0C BCL2L13 BET1 C1GALT1 C5orf46 CCDC167 CD300C CLDND2 CNIH3 CYB5B CYB5R3 CYP4F2 EMP3 FIS1 FXYD6-FXYD2 GIMAP5 HEXB HMOX1 HMOX2 IER3IP1 IFITM3 INSIG2 LNPEP LPAR3 MFF MS4A13 NINJ2 NKG7 ORMDL2 OTOP3 PLP2 PLPP6 RPRM RTP2 SERP1 SERP2 SLC16A13 SLC30A8 SLC35B4 SLC35G1 SMCO4 SMIM1 STATH STX6 STX7 SYNJ2BP TF TFRC TIMM23 TIMMDC1 TMEM107 TMEM11 TMEM140 TMEM187 TMEM19 TMIE UBE2J1 VAMP1 VAMP3 VAMP4 VKORC1 YIF1A ZDHHC21
Entrez ID		10228	116151
HPRD ID		07231	12737
Ensembl ID		ENSG00000135823	ENSG00000124098
Uniprot IDs		O43752	Q96KR6
PDB IDs		2NPS 4J2C
Enriched GO Terms of Interacting Partners?		Organelle Fusion Vesicle Fusion Organelle Membrane Fusion SNARE Complex Syntaxin Binding Membrane Fusion SNAP Receptor Activity Organelle Localization By Membrane Tethering Vesicle Organization Membrane Docking Vesicle Docking Vesicle-mediated Transport Membrane Organization Cytoplasmic Vesicle Establishment Of Protein Localization Protein Transport Intracellular Protein Transport Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Vesicle Fusion To Plasma Membrane Organelle Localization Cellular Localization Establishment Of Localization In Cell Synaptic Vesicle Membrane Organization Membrane SNARE Binding Intracellular Transport Synaptic Vesicle To Endosome Fusion Intracellular Protein Localization Endosome Organization Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Exocytosis Localization Within Membrane Vesicle Docking Involved In Exocytosis Lysosomal Membrane ATP-dependent Protein Binding Chloride Channel Inhibitor Activity CORVET Complex Azurophil Granule Membrane Endomembrane System Regulation Of Synaptic Vesicle Priming Azurophil Granule SNARE Complex Assembly Regulation Of Protein Localization Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway HOPS Complex Endocytic Vesicle Early Endosome Regulation Of SNARE Complex Assembly Endosomal Vesicle Fusion Vesicle Targeting	Membrane Endoplasmic Reticulum Membrane SNARE Complex SNAP Receptor Activity Golgi Membrane Establishment Of Protein Localization Endoplasmic Reticulum Mitochondrial Outer Membrane Heme Oxidation Heme Oxygenase (decyclizing) Activity SNARE Complex Assembly Organelle Fusion Protein Binding Intracellular Chemical Homeostasis Nitric-oxide Synthase Complex Vesicle Fusion Synaptic Vesicle To Endosome Fusion Transport Vesicle Organelle Membrane Fusion Monoatomic Cation Homeostasis Monoatomic Ion Homeostasis Chemical Homeostasis Proton-transporting Two-sector ATPase Complex, Proton-transporting Domain Intracellular Monoatomic Cation Homeostasis Nitrite Reductase (NO-forming) Activity Multicellular Organismal-level Iron Ion Homeostasis Clathrin-coated Endocytic Vesicle Membrane Protein Targeting Multicellular Organismal-level Chemical Homeostasis Cellular Homeostasis Intracellular Monoatomic Ion Homeostasis Recycling Endosome Protein Targeting To Mitochondrion Nitric Oxide Metabolic Process Plasma Membrane Reactive Nitrogen Species Metabolic Process Membrane Fusion Cholesterol Biosynthetic Process HFE-transferrin Receptor Complex Negative Regulation Of Fatty Acid Transport Golgi Lumen Acidification Vacuolar Proton-transporting V-type ATPase, V0 Domain Proton-transporting V-type ATPase, V0 Domain Sterol Biosynthetic Process Bleb Assembly Heme Catabolic Process Response To Type II Interferon Golgi Vesicle Transport Azurophil Granule Protein Transport
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