STX6 and GOLM2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		STX6	GOLM2
Description		syntaxin 6	golgi membrane protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleoplasm Endosome Early Endosome Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Endomembrane System Membrane Clathrin-coated Vesicle Synaptic Vesicle Membrane Organelle Membrane SNARE Complex Vesicle Trans-Golgi Network Membrane Phagocytic Vesicle Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane	Golgi Apparatus Membrane
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Intracellular Protein Transport Vesicle Fusion Endosome Organization Protein Transport Synaptic Vesicle To Endosome Fusion Vesicle-mediated Transport Endocytic Recycling Regulation Of Protein Localization Retrograde Transport, Endosome To Golgi Golgi Vesicle Transport Vesicle Docking
Pathways		Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Creutzfeldt-Jakob disease (sporadic) ( 32949544) Intralaminar thalamic nuclei volume ( 34006833) Menopause (age at onset) ( 26414677) Progressive supranuclear palsy ( 21685912 30089514) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		33 interacting genes: AQP6 ARMC8 DNAJC5 EBP EEA1 FAM210B GOLM2 GOPC LIME1 LMNA MARCHF2 MEOX2 MMGT1 MTERF2 MTIF3 NAPB PSMA3 PTPN9 SCN3B SNAP23 SNAP29 STOM STX16 STX1A STX2 STX7 TIMMDC1 TMEM14B TMEM205 TMEM86B VAMP4 VPS11 VPS18	17 interacting genes: APP B3GNT7 C3orf52 EMD GOLPH3 GOLPH3L GSK3B LRP10 NXPE3 RNASE12 SOD3 STX1A STX6 TMEM201 TMEM42 TRAF3IP3 VDR
Entrez ID		10228	113201
HPRD ID		07231	11018
Ensembl ID		ENSG00000135823	ENSG00000166734
Uniprot IDs		O43752	Q6P4E1
PDB IDs		2NPS 4J2C
Enriched GO Terms of Interacting Partners?		Organelle Fusion Vesicle Fusion Organelle Membrane Fusion SNARE Complex Syntaxin Binding Membrane Fusion SNAP Receptor Activity Organelle Localization By Membrane Tethering Vesicle Organization Membrane Docking Vesicle Docking Vesicle-mediated Transport Membrane Organization Cytoplasmic Vesicle Establishment Of Protein Localization Protein Transport Intracellular Protein Transport Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Vesicle Fusion To Plasma Membrane Organelle Localization Cellular Localization Establishment Of Localization In Cell Synaptic Vesicle Membrane Organization Membrane SNARE Binding Intracellular Transport Synaptic Vesicle To Endosome Fusion Intracellular Protein Localization Endosome Organization Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Exocytosis Localization Within Membrane Vesicle Docking Involved In Exocytosis Lysosomal Membrane ATP-dependent Protein Binding Chloride Channel Inhibitor Activity CORVET Complex Azurophil Granule Membrane Endomembrane System Regulation Of Synaptic Vesicle Priming Azurophil Granule SNARE Complex Assembly Regulation Of Protein Localization Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway HOPS Complex Endocytic Vesicle Early Endosome Regulation Of SNARE Complex Assembly Endosomal Vesicle Fusion Vesicle Targeting	Regulation Of Protein Transport Positive Regulation Of Protein Transport Membrane Organization Protein Targeting To Golgi Apparatus Golgi Vesicle Budding Cargo Adaptor Activity Regulation Of Establishment Of Protein Localization Positive Regulation Of Establishment Of Protein Localization Regulation Of Protein Localization Cortical Endoplasmic Reticulum Golgi Cisterna Positive Regulation Of Protein Localization Positive Regulation Of Transport Spindle Pole Centrosome Trans-Golgi Network Membrane Golgi Apparatus Positive Regulation Of Protein Export From Nucleus Vesicle Organization Negative Regulation Of Canonical Wnt Signaling Pathway Vesicle-mediated Transport To The Plasma Membrane Golgi Membrane Amyloid Fibril Formation Phosphatidylinositol-4-phosphate Binding Positive Regulation Of Excitatory Postsynaptic Potential Regulation Of Transport Vesicle Budding From Membrane Negative Regulation Of Wnt Signaling Pathway Vesicle-mediated Transport Regulation Of Protein Export From Nucleus SNAP Receptor Activity Golgi To Plasma Membrane Protein Transport Amyloid-beta Complex Growth Cone Lamellipodium Neuron Projection Organization Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Long-term Synaptic Potentiation TMEM240-body Regulation Of Microtubule Anchoring At Centrosome SNARE Complex Myosin Head/neck Binding Calcitriol Binding Lithocholic Acid Binding Trans-Golgi Network Negative Regulation Of Protein Localization To Nucleus Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Modulation Of Excitatory Postsynaptic Potential Nuclear Inner Membrane Cellular Response To Amyloid-beta
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