STX6 and STX7

Number of citations of the paper that reports this interaction (PMID 11278762)
20

Data Source:
HPRD (in vivo)

		STX6	STX7
Gene Name		syntaxin 6	syntaxin 7
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Early Endosome Golgi Apparatus Trans-Golgi Network Plasma Membrane Integral Component Of Membrane Clathrin-coated Vesicle SNARE Complex Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm	Immunological Synapse Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Plasma Membrane Endomembrane System Integral Component Of Membrane Endocytic Vesicle SNARE Complex Early Endosome Membrane Vesicle Azurophil Granule Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome Extracellular Vesicular Exosome Tertiary Granule
	Molecular Function	SNAP Receptor Activity Protein Binding Syntaxin Binding	SNARE Binding SNAP Receptor Activity Chloride Channel Inhibitor Activity Syntaxin Binding
	Biological Process	Intracellular Protein Transport Vesicle Fusion Endosome Organization Regulation Of Protein Localization Retrograde Transport, Endosome To Golgi Golgi Vesicle Transport Golgi Ribbon Formation	Positive Regulation Of T Cell Mediated Cytotoxicity Intracellular Protein Transport Vesicle Fusion Vesicle Docking Organelle Localization Organelle Assembly Positive Regulation Of Receptor Localization To Synapse Regulation Of Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases
GWAS		Progressive supranuclear palsy ( 21685912)
Protein-Protein Interactions		15 interactors: EEA1 GOPC GOSR2 MARCH2 NAPB PSMA3 PTPN9 SNAP23 SNAP29 STX16 STX4 STX7 VAMP4 VPS11 VPS18	13 interactors: ENTPD2 MAPK6 NAPA SNAP29 STX4 STX6 STX8 VAMP7 VAMP8 VPS11 VPS16 VPS18 VTI1B
Entrez ID		10228	8417
HPRD ID		07231	04449
Ensembl ID		ENSG00000135823
Uniprot IDs		B4DR17 O43752	O15400
PDB IDs		2NPS
Enriched GO Terms of Interacting Partners?		Vesicle Fusion Membrane Fusion Organelle Fusion Vesicle-mediated Transport Vesicle Organization Establishment Of Localization In Cell Membrane Organization Cellular Localization Protein Transport Establishment Of Protein Localization Intracellular Transport Protein Localization Regulation Of Protein Localization To Plasma Membrane Synaptic Vesicle Fusion To Presynaptic Membrane Transport Vesicle Docking Post-Golgi Vesicle-mediated Transport Membrane Docking Golgi Vesicle Transport Cellular Protein Localization Synaptic Vesicle Transport Intracellular Protein Transport Exocytosis Regulation Of Establishment Of Protein Localization To Plasma Membrane Organelle Organization Organelle Localization Synaptic Vesicle Exocytosis Establishment Of Vesicle Localization Golgi Ribbon Formation Vesicle Localization Secretion By Cell Regulation Of Golgi To Plasma Membrane Protein Transport Synaptic Vesicle Priming SNARE Complex Assembly Secretion Neurotransmitter Secretion Establishment Of Organelle Localization Cellular Protein Complex Assembly Regulation Of Vesicle-mediated Transport Regulation Of Neurotransmitter Levels Neurotransmitter Transport Endosomal Transport Protein Complex Assembly Vesicle Targeting Synaptic Transmission Intra-Golgi Vesicle-mediated Transport Cellular Macromolecular Complex Assembly Cellular Component Assembly Synaptic Vesicle To Endosome Fusion Cytoplasmic Sequestering Of CFTR Protein	Vesicle Fusion Membrane Fusion Organelle Fusion Protein Transport Establishment Of Protein Localization Vesicle Organization Protein Localization Intracellular Protein Transport Establishment Of Localization In Cell Vesicle-mediated Transport Intracellular Transport Post-Golgi Vesicle-mediated Transport Cellular Localization Golgi Vesicle Transport Membrane Organization Cellular Protein Localization SNARE Complex Assembly Exocytosis Regulation Of Protein Localization To Plasma Membrane Regulation Of Vesicle-mediated Transport Endosomal Transport Secretion By Cell Positive Regulation Of Regulated Secretory Pathway Secretion Positive Regulation Of Histamine Secretion By Mast Cell Regulation Of Histamine Secretion By Mast Cell Regulation Of Exocytosis Regulation Of Regulated Secretory Pathway Viral Entry Into Host Cell Entry Into Host Cell Regulation Of Cellular Component Organization Transport Regulation Of Protein Localization Positive Regulation Of Exocytosis Regulation Of SNARE Complex Assembly Autophagic Vacuole Fusion Vesicle Fusion With Golgi Apparatus Regulation Of Cellular Localization Vacuolar Transport Vesicle Docking Synaptic Vesicle Fusion To Presynaptic Membrane Membrane Docking Positive Regulation Of Mast Cell Degranulation Interaction With Host Positive Regulation Of Hormone Secretion Positive Regulation Of Mast Cell Activation Cellular Protein Complex Assembly Organelle Organization Regulation Of Mast Cell Degranulation Endosome To Lysosome Transport
Tagcloud ?		alpha5beta1 alphavbeta3 boundaries c1 cho cholesterol endosome endosomes export hamster imbalance integrins interferes niemann npc1 ovary pick rab11 re recycling res restoration restores snare syntaxin tgn transferrin tuning vamp3	cd3 ctls eliminate exocytosis granules granzymes groundwork laying lgs lytic nsf perforin snap snare snares stx13 stx16 stx3 stx4 stx6 stx8 synapse synapses syntaxin1b2 tumorigenic vamp3 vamp4 vesicle vti1b
Tagcloud (Difference) ?		alpha5beta1 alphavbeta3 boundaries c1 cho cholesterol endosome endosomes export hamster imbalance integrins interferes niemann npc1 ovary pick rab11 re recycling res restoration restores syntaxin tgn transferrin tuning	cd3 ctls eliminate exocytosis granules granzymes groundwork laying lgs lytic nsf perforin snap snares stx13 stx16 stx3 stx4 stx8 synapse synapses syntaxin1b2 tumorigenic vamp4 vesicle vti1b
Tagcloud (Intersection) ?		snare stx6 vamp3