STX6 and VAMP4

Number of citations of the paper that reports this interaction (PMID 11839770)
115

Data Source:
HPRD (in vitro, in vivo)

		STX6	VAMP4
Gene Name		syntaxin 6	vesicle-associated membrane protein 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Early Endosome Golgi Apparatus Trans-Golgi Network Plasma Membrane Integral Component Of Membrane Clathrin-coated Vesicle SNARE Complex Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm	Golgi Membrane Lysosome Endosome Golgi Apparatus Trans-Golgi Network Cell Surface Integral Component Of Membrane SNARE Complex
	Molecular Function	SNAP Receptor Activity Protein Binding Syntaxin Binding	SNARE Binding SNAP Receptor Activity
	Biological Process	Intracellular Protein Transport Vesicle Fusion Endosome Organization Regulation Of Protein Localization Retrograde Transport, Endosome To Golgi Golgi Vesicle Transport Golgi Ribbon Formation	Microtubule Cytoskeleton Organization Exocytosis ER To Golgi Vesicle-mediated Transport SNARE Complex Assembly Regulation Of Golgi To Plasma Membrane Protein Transport Golgi To Plasma Membrane Protein Transport Golgi Ribbon Formation
Pathways
Drugs
Diseases
GWAS		Progressive supranuclear palsy ( 21685912)
Protein-Protein Interactions		15 interactors: EEA1 GOPC GOSR2 MARCH2 NAPB PSMA3 PTPN9 SNAP23 SNAP29 STX16 STX4 STX7 VAMP4 VPS11 VPS18	9 interactors: AP1M1 BCL2L13 CCDC155 CSNK2A1 PACS1 SNAP29 STX16 STX4 STX6
Entrez ID		10228	8674
HPRD ID		07231	06070
Ensembl ID		ENSG00000135823	ENSG00000117533
Uniprot IDs		B4DR17 O43752	O75379 Q6IAZ3
PDB IDs		2NPS
Enriched GO Terms of Interacting Partners?		Vesicle Fusion Membrane Fusion Organelle Fusion Vesicle-mediated Transport Vesicle Organization Establishment Of Localization In Cell Membrane Organization Cellular Localization Protein Transport Establishment Of Protein Localization Intracellular Transport Protein Localization Regulation Of Protein Localization To Plasma Membrane Synaptic Vesicle Fusion To Presynaptic Membrane Transport Vesicle Docking Post-Golgi Vesicle-mediated Transport Membrane Docking Golgi Vesicle Transport Cellular Protein Localization Synaptic Vesicle Transport Intracellular Protein Transport Exocytosis Regulation Of Establishment Of Protein Localization To Plasma Membrane Organelle Organization Organelle Localization Synaptic Vesicle Exocytosis Establishment Of Vesicle Localization Golgi Ribbon Formation Vesicle Localization Secretion By Cell Regulation Of Golgi To Plasma Membrane Protein Transport Synaptic Vesicle Priming SNARE Complex Assembly Secretion Neurotransmitter Secretion Establishment Of Organelle Localization Cellular Protein Complex Assembly Regulation Of Vesicle-mediated Transport Regulation Of Neurotransmitter Levels Neurotransmitter Transport Endosomal Transport Protein Complex Assembly Vesicle Targeting Synaptic Transmission Intra-Golgi Vesicle-mediated Transport Cellular Macromolecular Complex Assembly Cellular Component Assembly Synaptic Vesicle To Endosome Fusion Cytoplasmic Sequestering Of CFTR Protein	Vesicle Fusion Vesicle Organization Organelle Fusion Golgi Vesicle Transport Membrane Fusion Membrane Organization Establishment Of Localization In Cell Golgi Ribbon Formation Protein Transport Cellular Localization Vesicle-mediated Transport Establishment Of Protein Localization Synaptic Vesicle Fusion To Presynaptic Membrane Intracellular Protein Transport Protein Localization Regulation Of Defense Response To Virus By Virus Endosomal Transport Cellular Protein Localization Intracellular Transport Intra-Golgi Vesicle-mediated Transport Synaptic Vesicle Exocytosis Establishment Of Organelle Localization Retrograde Transport, Endosome To Golgi Organelle Organization Golgi Organization Chromosome Localization To Nuclear Envelope Involved In Synapsis Organelle Localization Vesicle Docking Regulation Of Defense Response To Virus Endomembrane System Organization Post-Golgi Vesicle-mediated Transport Membrane Docking Neurotransmitter Secretion Synaptic Vesicle Transport Positive Regulation Of Eosinophil Degranulation Regulation Of Neurotransmitter Levels Neurotransmitter Transport Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Establishment Of Vesicle Localization Regulation Of Cysteine-type Endopeptidase Activity Vesicle Localization Positive Regulation Of Protein Localization To Cell Surface Autophagic Vacuole Fusion Pigment Granule Maturation Endosome To Melanosome Transport Positive Regulation Of Immunoglobulin Secretion Synaptic Vesicle Priming Transport Cellular Pigment Accumulation SNARE Complex Assembly
Tagcloud ?		alpha5beta1 alphavbeta3 boundaries c1 cho cholesterol endosome endosomes export hamster imbalance integrins interferes niemann npc1 ovary pick rab11 re recycling res restoration restores snare syntaxin tgn transferrin tuning vamp3	adm adriamycin arrb2 bigger cblb chip cryopreservation doubling effectors endoperoxide exocytosis exudation gliomas impulse ingestion mdr medip ontology pard6b pgp pkcalpha rh123 sgh snap47 tgfb1 vamp3 verify vps4b wizened
Tagcloud (Difference) ?		alpha5beta1 alphavbeta3 boundaries c1 cho cholesterol endosome endosomes export hamster imbalance integrins interferes niemann npc1 ovary pick rab11 re recycling res restoration restores snare syntaxin tgn transferrin tuning	adm adriamycin arrb2 bigger cblb chip cryopreservation doubling effectors endoperoxide exocytosis exudation gliomas impulse ingestion mdr medip ontology pard6b pgp pkcalpha rh123 sgh snap47 tgfb1 verify vps4b wizened
Tagcloud (Intersection) ?		vamp3