Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
ARPC2 and WAS
Number of citations of the paper that reports this interaction (PMID
11943145
)
5
Data Source:
BioGRID
(pull down)
ARPC2
WAS
Gene Name
actin related protein 2/3 complex, subunit 2, 34kDa
Wiskott-Aldrich syndrome
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Endosome
Golgi Apparatus
Cytosol
Arp2/3 Protein Complex
Plasma Membrane
Focal Adhesion
Actin Cytoskeleton
Cell Leading Edge
Neuron Projection
Synapse
Extracellular Vesicular Exosome
Cytosol
Cell-cell Junction
Vesicle Membrane
Actin Cytoskeleton
Extracellular Vesicular Exosome
Molecular Function
Structural Constituent Of Cytoskeleton
Protein Binding
Kinesin Binding
AP-1 Adaptor Complex Binding
Actin Filament Binding
Arp2/3 Complex Binding
Actin Binding
Small GTPase Regulator Activity
Protein Binding
SH3 Domain Binding
Protein Kinase Binding
Identical Protein Binding
Phospholipase Binding
Biological Process
Movement Of Cell Or Subcellular Component
Axon Guidance
Positive Regulation Of Lamellipodium Assembly
Arp2/3 Complex-mediated Actin Nucleation
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Innate Immune Response
Ephrin Receptor Signaling Pathway
Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Protein Complex Assembly
Defense Response
Immune Response
Blood Coagulation
Actin Polymerization Or Depolymerization
Epidermis Development
Endosomal Transport
Actin Filament Polymerization
Actin Filament-based Movement
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
T Cell Activation
Innate Immune Response
Regulation Of Catalytic Activity
T Cell Receptor Signaling Pathway
Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways
EPHB-mediated forward signaling
Axon guidance
EPH-Ephrin signaling
Fcgamma receptor (FCGR) dependent phagocytosis
Regulation of actin dynamics for phagocytic cup formation
Innate Immune System
TCR signaling
Generation of second messenger molecules
Fcgamma receptor (FCGR) dependent phagocytosis
Regulation of actin dynamics for phagocytic cup formation
Innate Immune System
Adaptive Immune System
Drugs
Diseases
GWAS
Inflammatory bowel disease (
23128233
)
Obesity-related traits (
23251661
)
Protein-Protein Interactions
6 interactors:
ACTR3
ARPC1B
ARPC4
AURKA
CORO1B
WAS
53 interactors:
ABI3
ACTC1
APBB1
APPBP2
ARHGAP1
ARHGEF7
ARPC1B
ARPC2
ARPC3
BAIAP2L1
BTK
C5AR1
CDC42
CIB1
CRKL
CSNK2A1
CSNK2A2
DLG1
ENAH
EVL
FCHSD2
FGR
FYB
FYN
GAS7
GRB2
HCK
HCLS1
ITK
ITSN2
LCK
LCP2
NCK1
NCK2
NCKIPSD
PIK3R1
PLCG1
PRPF40A
PSTPIP1
PTPN12
RAC1
RGS14
RHOJ
SORBS2
SRC
TCERG1
TEC
TNK2
TRIP10
VASP
WBP4
WIPF1
WIPF2
Entrez ID
10109
7454
HPRD ID
10367
02314
Ensembl ID
ENSG00000163466
ENSG00000015285
Uniprot IDs
O15144
Q53R19
P42768
PDB IDs
1CEE
1EJ5
1T84
2A3Z
2K42
2OT0
Enriched GO Terms of Interacting Partners
?
Regulation Of Cytoskeleton Organization
Actin Filament Organization
Regulation Of Organelle Organization
Regulation Of Actin Cytoskeleton Organization
Positive Regulation Of Organelle Organization
Regulation Of Actin Filament-based Process
Cytoskeleton Organization
Arp2/3 Complex-mediated Actin Nucleation
Actin Cytoskeleton Organization
Positive Regulation Of Cytoskeleton Organization
Actin Filament-based Process
Actin Nucleation
Regulation Of Cellular Component Organization
Positive Regulation Of Actin Filament Polymerization
Positive Regulation Of Protein Polymerization
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Movement Of Cell Or Subcellular Component
Organelle Organization
Fc-gamma Receptor Signaling Pathway
Positive Regulation Of Protein Complex Assembly
Fc Receptor Mediated Stimulatory Signaling Pathway
Regulation Of Actin Filament Polymerization
Positive Regulation Of Lamellipodium Organization
Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Regulation Of Actin Polymerization Or Depolymerization
Regulation Of Actin Filament Length
Regulation Of Actin Nucleation
Phagocytosis
Fc Receptor Signaling Pathway
Immune Response-activating Cell Surface Receptor Signaling Pathway
Positive Regulation Of Cellular Component Biogenesis
Regulation Of Cellular Component Size
Actin Filament Polymerization
Regulation Of Protein Complex Assembly
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Cell Projection Organization
Immune Response-regulating Signaling Pathway
Actin Polymerization Or Depolymerization
Ephrin Receptor Signaling Pathway
Negative Regulation Of Spindle Checkpoint
Protein Polymerization
Chemotaxis
Neuron Projection Morphogenesis
Positive Regulation Of Immune Response
Endocytosis
Protein Localization To Cell Leading Edge
Spindle Assembly Involved In Female Meiosis I
Cellular Component Assembly
Negative Regulation Of Cytoskeleton Organization
Meiotic Nuclear Division
Immune Response-activating Cell Surface Receptor Signaling Pathway
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Immune Response-regulating Signaling Pathway
Fc Receptor Signaling Pathway
Movement Of Cell Or Subcellular Component
Positive Regulation Of Immune Response
Positive Regulation Of Immune System Process
Regulation Of Immune System Process
Locomotion
Axon Guidance
Regulation Of Immune Response
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Immune System Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Actin Filament Organization
Innate Immune Response
Chemotaxis
Positive Regulation Of Actin Filament Polymerization
Axonogenesis
Neuron Projection Morphogenesis
Immune Response
Positive Regulation Of Protein Polymerization
Enzyme Linked Receptor Protein Signaling Pathway
Axon Development
Actin Cytoskeleton Organization
Cell Morphogenesis Involved In Neuron Differentiation
Phagocytosis
Positive Regulation Of Protein Complex Assembly
Cell Morphogenesis Involved In Differentiation
Cytoskeleton Organization
Actin Filament-based Process
Regulation Of Actin Filament Polymerization
Cell Surface Receptor Signaling Pathway
Endocytosis
Peptidyl-tyrosine Autophosphorylation
Positive Regulation Of Cytoskeleton Organization
Regulation Of Actin Polymerization Or Depolymerization
Regulation Of Protein Complex Assembly
Regulation Of Actin Filament Length
Neuron Projection Development
Regulation Of Cellular Component Organization
Antigen Receptor-mediated Signaling Pathway
Cell Projection Morphogenesis
Cell Part Morphogenesis
Response To External Stimulus
Signal Transduction
T Cell Receptor Signaling Pathway
Signaling
Tagcloud
?
10q26
alleles
carrying
colitis
constructed
contribution
dra
dutch
ecm1
flagged
gas7
genotyped
gwas
hla
il10
il23r
loci
make
replicated
replication
s100z
snps
susceptibility
tagging
ten
top
trend
uc
ulcerative
Tagcloud (Difference)
?
10q26
alleles
carrying
colitis
constructed
contribution
dra
dutch
ecm1
flagged
gas7
genotyped
gwas
hla
il10
il23r
loci
make
replicated
replication
s100z
snps
susceptibility
tagging
ten
top
trend
uc
ulcerative
Tagcloud (Intersection)
?