ARPC2 and CORO1B

Number of citations of the paper that reports this interaction (PMID 17350576)
61

Data Source:
HPRD (in vivo, in vitro)

		ARPC2	CORO1B
Gene Name		actin related protein 2/3 complex, subunit 2, 34kDa	coronin, actin binding protein, 1B
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Endosome Golgi Apparatus Cytosol Arp2/3 Protein Complex Plasma Membrane Focal Adhesion Actin Cytoskeleton Cell Leading Edge Neuron Projection Synapse Extracellular Vesicular Exosome	Stress Fiber Cytoplasm Actin Filament Plasma Membrane Focal Adhesion Actin Cytoskeleton Lamellipodium Cell Leading Edge Extracellular Vesicular Exosome
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Kinesin Binding AP-1 Adaptor Complex Binding Actin Filament Binding Arp2/3 Complex Binding	Protein Binding Identical Protein Binding Actin Filament Binding Arp2/3 Complex Binding
	Biological Process	Movement Of Cell Or Subcellular Component Axon Guidance Positive Regulation Of Lamellipodium Assembly Arp2/3 Complex-mediated Actin Nucleation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Innate Immune Response Ephrin Receptor Signaling Pathway Positive Regulation Of Substrate Adhesion-dependent Cell Spreading	Cell Migration Actin Cytoskeleton Organization Ruffle Organization Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Endothelial Cell Chemotaxis Wound Healing Actin Filament Bundle Assembly Actin Filament Branching Protein Localization To Cell Leading Edge Positive Regulation Of Lamellipodium Morphogenesis
Pathways		EPHB-mediated forward signaling Axon guidance EPH-Ephrin signaling Fcgamma receptor (FCGR) dependent phagocytosis Regulation of actin dynamics for phagocytic cup formation Innate Immune System
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233) Obesity-related traits ( 23251661)
Protein-Protein Interactions		6 interactors: ACTR3 ARPC1B ARPC4 AURKA CORO1B WAS	6 interactors: ARPC2 KPNA2 POLR1C PRKCA SSH1 TERF1
Entrez ID		10109	57175
HPRD ID		10367	16743
Ensembl ID		ENSG00000163466	ENSG00000172725
Uniprot IDs		O15144 Q53R19	Q9BR76
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cytoskeleton Organization Actin Filament Organization Regulation Of Organelle Organization Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Cytoskeleton Organization Arp2/3 Complex-mediated Actin Nucleation Actin Cytoskeleton Organization Positive Regulation Of Cytoskeleton Organization Actin Filament-based Process Actin Nucleation Regulation Of Cellular Component Organization Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Protein Polymerization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Movement Of Cell Or Subcellular Component Organelle Organization Fc-gamma Receptor Signaling Pathway Positive Regulation Of Protein Complex Assembly Fc Receptor Mediated Stimulatory Signaling Pathway Regulation Of Actin Filament Polymerization Positive Regulation Of Lamellipodium Organization Regulation Of Arp2/3 Complex-mediated Actin Nucleation Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Regulation Of Actin Nucleation Phagocytosis Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Cellular Component Biogenesis Regulation Of Cellular Component Size Actin Filament Polymerization Regulation Of Protein Complex Assembly Immune Response-regulating Cell Surface Receptor Signaling Pathway Cell Projection Organization Immune Response-regulating Signaling Pathway Actin Polymerization Or Depolymerization Ephrin Receptor Signaling Pathway Negative Regulation Of Spindle Checkpoint Protein Polymerization Chemotaxis Neuron Projection Morphogenesis Positive Regulation Of Immune Response Endocytosis Protein Localization To Cell Leading Edge Spindle Assembly Involved In Female Meiosis I Cellular Component Assembly Negative Regulation Of Cytoskeleton Organization Meiotic Nuclear Division	Regulation Of Lamellipodium Assembly Positive Regulation Of Cellular Component Biogenesis Regulation Of Cytoskeleton Organization Positive Regulation Of Dense Core Granule Biogenesis Positive Regulation Of Protein Polymerization Positive Regulation Of Mitotic Cell Cycle Regulation Of Cell Projection Assembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Histone H3-T6 Phosphorylation Innate Immune Response Telomeric Loop Formation Age-dependent Telomere Shortening Positive Regulation Of Protein Complex Assembly Telomere Maintenance Via Telomere Shortening Regulation Of Organelle Organization Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Negative Regulation Of Telomere Maintenance Via Telomerase Peptidyl-serine Autophosphorylation Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Response To Stimulus Positive Regulation Of Cell Cycle Desmosome Assembly Replicative Cell Aging Cellular Response To ATP Negative Regulation Of Glial Cell Apoptotic Process Negative Regulation Of Transferase Activity Regulation Of Nuclear Cell Cycle DNA Replication Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Cellular Component Size Negative Regulation Of Glucose Import Regulation Of Telomere Maintenance Via Telomerase Regulation Of Protein Complex Assembly Immune Response Positive Regulation Of Macrophage Differentiation Defense Response Desmosome Organization Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Microtubule Polymerization Positive Regulation Of Cell Adhesion Organelle Organization Regulation Of Telomerase Activity Positive Regulation Of Lamellipodium Assembly Termination Of RNA Polymerase III Transcription Transcription Elongation From RNA Polymerase III Promoter Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process
Tagcloud ?		10q26 alleles carrying colitis constructed contribution dra dutch ecm1 flagged gas7 genotyped gwas hla il10 il23r loci make replicated replication s100z snps susceptibility tagging ten top trend uc ulcerative	abomasum actb b2m blat butterfat calculating cops7a cows dnajc19 eif3k emd gapdh genorm golga5 goodness gpr175 icg linoleic lipogenic marveld1 mine mrpl39 mtg1 normalization qpcr supplements unsupplemented uxt verification
Tagcloud (Difference) ?		10q26 alleles carrying colitis constructed contribution dra dutch ecm1 flagged gas7 genotyped gwas hla il10 il23r loci make replicated replication s100z snps susceptibility tagging ten top trend uc ulcerative	abomasum actb b2m blat butterfat calculating cops7a cows dnajc19 eif3k emd gapdh genorm golga5 goodness gpr175 icg linoleic lipogenic marveld1 mine mrpl39 mtg1 normalization qpcr supplements unsupplemented uxt verification
Tagcloud (Intersection) ?