OASL

Gene Name		2-5-oligoadenylate synthetase-like
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Gene Ontology Annotations	Cellular Component	Nucleolus Cytoplasm Cytosol Membrane
	Molecular Function	2'-5'-oligoadenylate Synthetase Activity DNA Binding Double-stranded RNA Binding ATP Binding Poly(A) RNA Binding Thyroid Hormone Receptor Binding
	Biological Process	Metabolic Process Response To Virus Cytokine-mediated Signaling Pathway Negative Regulation Of Viral Genome Replication Defense Response To Virus Interferon-gamma-mediated Signaling Pathway Type I Interferon Signaling Pathway
Pathways		Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system Interferon alpha/beta signaling
Drugs
Diseases
GWAS		C-reactive protein ( 22939635) Cardiovascular disease risk factors ( 21943158) N-glycan levels ( 21203500)
Protein-protein Interactions		3 interactors: MBD1 SEZ6L2 THRA
Entrez ID		8638
HPRD ID		04473
Ensembl ID		ENSG00000135114
Uniprot IDs		Q15646
PDB IDs		1WH3
Enriched GO Terms of Interacting Partners?		Negative Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Positive Regulation Of Female Receptivity Negative Regulation Of DNA-templated Transcription, Initiation Negative Regulation Of Transcription Initiation From RNA Polymerase II Promoter Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Female Courtship Behavior Regulation Of Thyroid Hormone Mediated Signaling Pathway Regulation Of Female Receptivity Female Mating Behavior Type I Pneumocyte Differentiation Transcription From RNA Polymerase II Promoter Cytoplasmic Sequestering Of Transcription Factor Cytoplasmic Sequestering Of Protein Cartilage Condensation Regulation Of DNA-templated Transcription, Initiation Thyroid Gland Development Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Myotube Differentiation Mating Behavior Regulation Of Myeloid Cell Apoptotic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription Factor Import Into Nucleus Mating Response To Cold Regulation Of Lipid Catabolic Process Regulation Of Myotube Differentiation Lung Epithelial Cell Differentiation Positive Regulation Of Striated Muscle Cell Differentiation Lung Cell Differentiation Lung Epithelium Development Negative Regulation Of Protein Import Into Nucleus Negative Regulation Of Protein Localization To Nucleus Positive Regulation Of Muscle Cell Differentiation Negative Regulation Of Intracellular Protein Transport Regulation Of Transcription Factor Import Into Nucleus Negative Regulation Of Cellular Metabolic Process Regulation Of Striated Muscle Cell Differentiation Erythrocyte Differentiation Steroid Hormone Mediated Signaling Pathway Erythrocyte Homeostasis Transcription, DNA-templated Negative Regulation Of Intracellular Transport RNA Biosynthetic Process Negative Regulation Of Protein Complex Assembly Myeloid Cell Homeostasis Hormone-mediated Signaling Pathway Maintenance Of Protein Location In Cell
Tagcloud ?		4a abrogate adaptor altogether antiviral argue cardif ccl5 cleaving compromised counteracts cxcl10 cxcl11 cxcl9 ectopically evasion hcv hepatocytes ifnbeta il28a il29 impairing innate irf3 isg15 isg56 isgs ns3 polyprotein