OASL

Description		2'-5'-oligoadenylate synthetase like
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Membrane
	Molecular Function	2'-5'-oligoadenylate Synthetase Activity DNA Binding RNA Binding Double-stranded RNA Binding Protein Binding Nucleotidyltransferase Activity Nuclear Thyroid Hormone Receptor Binding
	Biological Process	Immune System Process Response To Virus Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus Type I Interferon-mediated Signaling Pathway Interleukin-27-mediated Signaling Pathway Defense Response To Other Organism Antiviral Innate Immune Response Positive Regulation Of RIG-I Signaling Pathway
Pathways		Interferon gamma signaling OAS antiviral response Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) C-reactive protein ( 22939635) C-reactive protein levels ( 24763700 30388399) Cardiovascular disease risk factors ( 21943158) Hematocrit ( 32888494) Hemoglobin ( 32888494) N-glycan levels ( 21203500 21908519) Serum metabolite levels ( 23093944) Type 2 diabetes ( 30054458)
Interacting Genes		4 interacting genes: FILNC1 MBD1 SEZ6L2 THRA
Entrez ID		8638
HPRD ID		04473
Ensembl ID		ENSG00000135114
Uniprot IDs		A0A7P0T9H8 Q15646
PDB IDs		1WH3 4XQ7
Enriched GO Terms of Interacting Partners?		Negative Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Thyroid Hormone Receptor Signaling Pathway Female Courtship Behavior Positive Regulation Of Thyroid Hormone Receptor Signaling Pathway Positive Regulation Of Female Receptivity Double-stranded Methylated DNA Binding Unmethylated CpG Binding Transcription By RNA Polymerase II Regulation Of Female Receptivity Regulation Of Thyroid Hormone Receptor Signaling Pathway Type I Pneumocyte Differentiation Female Mating Behavior Negative Regulation Of DNA-templated Transcription Initiation Thyroid Hormone Binding Negative Regulation Of Transcription Initiation By RNA Polymerase II Cerebellar Purkinje Cell Layer Development General Transcription Initiation Factor Binding DNA-templated Transcription Synapse Maturation Cell Aggregation Cartilage Condensation Mating Behavior Retinoic Acid Receptor Signaling Pathway Methyl-CpG Binding Lung Epithelial Cell Differentiation TBP-class Protein Binding Lung Cell Differentiation Thyroid Gland Development Regulation Of Myeloid Cell Apoptotic Process Reproductive Behavior DNA Methylation-dependent Constitutive Heterochromatin Formation Response To Cold
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