THOC1 and USHBP1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		THOC1	USHBP1
Gene Name		THO complex 1	Usher syndrome 1C binding protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Transcription Export Complex THO Complex THO Complex Part Of Transcription Export Complex Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Nuclear Speck Intercellular Bridge
	Molecular Function	DNA Binding RNA Binding Protein Binding	Protein Binding PDZ Domain Binding
	Biological Process	Regulation Of DNA Recombination Transcription, DNA-templated RNA Processing MRNA Processing MRNA Export From Nucleus Apoptotic Process Signal Transduction RNA Splicing Replication Fork Processing Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of DNA-templated Transcription, Elongation Viral MRNA Export From Host Cell Nucleus Negative Regulation Of Isotype Switching To IgA Isotypes Negative Regulation Of DNA Damage Checkpoint
Pathways
Drugs
Diseases
GWAS		Bipolar disorder and major depressive disorder (combined) ( 20351715)
Protein-Protein Interactions		13 interactors: ALYREF DHX8 FRA10AC1 IK MOAP1 RABGEF1 RB1 SAP30BP SF3B2 THOC5 TRIM54 USHBP1 WDR77	124 interactors: ABLIM1 AKAP9 ANKRD36BP1 ARFIP2 ARNT2 ATP5O BCL10 BET1 C10orf10 C1orf109 C1orf216 C6orf165 CCDC116 CCDC120 CCDC121 CCDC146 CCDC148 CCDC22 CCDC24 CCDC33 CCDC87 CCHCR1 CCNK CENPP CEP63 CEP68 CHCHD3 CNNM3 COPS4 COPS8 CTNNBIP1 CTTNBP2NL DTNB DYDC1 EIF4E2 ERCC1 EXOC7 EXOC8 FAM107A FAM110A FAM124B FANCG FATE1 FBF1 FTL GATAD2B GCC1 GFI1B GIT2 GMCL1P1 GNG4 GOLGA8EP GOLGA8F GPSM1 GPSM3 GTF2H1 HAUS1 HGS IFT20 IL16 IMP3 ING3 INPP1 INTS4 KANSL1 KIAA0753 KLC3 KLC4 KLHL38 KLHL42 KPNA2 KRT15 KRT19 KRT20 KRT31 KRT38 KRT40 KRT79 LENG1 LINC00526 MAGEB4 MCM7 MCRS1 MED28 MED4 MOS MRPS23 NCAPH2 NDC80 NDE1 NGFRAP1 NOC4L PARVG PMF1 PPP1R7 PPP2R5D PRC1 PRKAA2 RASAL2 RECK RIBC2 RNF20 SEC14L4 SERTAD3 SH2D4A SMARCD1 SMARCE1 STX11 SYNJ2BP THADA THOC1 TRIM54 TSG101 TUBGCP4 TXLNA TXLNB UBE2W UBXN11 USH1C VPS28 ZFYVE26 ZNF483 ZNF765 ZNRF2P1
Entrez ID		9984	83878
HPRD ID		09498	18276
Ensembl ID		ENSG00000079134	ENSG00000130307
Uniprot IDs		Q96FV9	G8JLM4 Q8N6Y0
PDB IDs		1WXP
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Processing Viral MRNA Export From Host Cell Nucleus Intracellular Transport Of Virus Positive Regulation Of DNA-templated Transcription, Elongation Viral Process RNA Metabolic Process Gene Expression Regulation Of DNA-templated Transcription, Elongation MRNA Export From Nucleus Negative Regulation Of Kit Signaling Pathway RNA Export From Nucleus Negative Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Sister Chromatid Biorientation Regulation Of Myeloid Leukocyte Differentiation Establishment Of Localization In Cell Nuclear Export MRNA Transport Regulation Of Centromere Complex Assembly Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Negative Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Nucleobase-containing Compound Metabolic Process Negative Regulation Of Epithelial Cell Proliferation Regulation Of Stem Cell Division Negative Regulation Of DNA Damage Checkpoint Maintenance Of Mitotic Sister Chromatid Cohesion Protein Insertion Into Mitochondrial Membrane Regulation Of Cohesin Localization To Chromatin Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development RNA Transport Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Localization Negative Regulation Of Interleukin-6 Secretion Attachment Of Mitotic Spindle Microtubules To Kinetochore Negative Regulation Of Mast Cell Degranulation Cellular Nitrogen Compound Metabolic Process Regulation Of MRNA Export From Nucleus Negative Regulation Of Mast Cell Activation Involved In Immune Response Regulation Of Myeloid Cell Differentiation Cellular Localization Primitive Hemopoiesis Viral Life Cycle Positive Regulation Of Mitotic Metaphase/anaphase Transition Glial Cell Apoptotic Process Intracellular Transport	Organelle Organization Cell Cycle Process Cell Cycle Cell Division Mitotic Cell Cycle Chromosome Organization Mitotic Cell Cycle Process Establishment Of Localization In Cell Cytoskeleton Organization Cellular Localization Microtubule-based Process Microtubule Cytoskeleton Organization Chromatin Organization Chromatin Modification G2/M Transition Of Mitotic Cell Cycle Spindle Organization Regulation Of Metabolic Process Intracellular Transport Of Virus Intracellular Transport Mitotic Nuclear Division Centrosome Organization Cellular Process Cullin Deneddylation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Establishment Of Spindle Orientation Microtubule Organizing Center Organization Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Protein Deneddylation Viral Protein Processing Establishment Of Cell Polarity Histone H4 Acetylation Spindle Localization Cellular Response To DNA Damage Stimulus Histone H4-K5 Acetylation Histone H4-K8 Acetylation Membrane Organization Histone H4-K16 Acetylation Nucleosome Disassembly ATP-dependent Chromatin Remodeling Nucleotide-excision Repair, DNA Damage Removal Microtubule Nucleation Organelle Fusion Protein Targeting To Vacuole Virion Assembly
Tagcloud ?		biogenesis compromises conjunction coordinated degraded destabilization elongation evolutionarily export inspired mammals manipulated manipulation modest molecularly nascent nedd4 package proteasome reconstituted ribonucleoprotein rnp rnps specify tend transcripts ubiquitinated
Tagcloud (Difference) ?		biogenesis compromises conjunction coordinated degraded destabilization elongation evolutionarily export inspired mammals manipulated manipulation modest molecularly nascent nedd4 package proteasome reconstituted ribonucleoprotein rnp rnps specify tend transcripts ubiquitinated
Tagcloud (Intersection) ?