THOC1 and CTAG1B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		THOC1	CTAG1B
Description		THO complex subunit 1	cancer/testis antigen 1B
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GO Annotations	Cellular Component	Transcription Export Complex THO Complex THO Complex Part Of Transcription Export Complex Chromosome, Telomeric Region Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Nuclear Speck	Cytoplasm
	Molecular Function	DNA Binding RNA Binding Protein Binding Identical Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	MRNA Processing MRNA Export From Nucleus Apoptotic Process Signal Transduction RNA Splicing MRNA Transport	TRNA Threonylcarbamoyladenosine Metabolic Process
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Bipolar disorder ( 20351715) Bipolar disorder or major depressive disorder ( 20351715) Height ( 31562340) Menarche (age at onset) ( 29773799) Triglyceride levels ( 32203549)
Interacting Genes		32 interacting genes: AGR2 AKAP9 CTAG1A CTAG1B DHX8 ESS2 EXOC5 EXOSC7 FRA10AC1 GPRASP3 IK MAGEB4 MOAP1 MTNR1B NEDD4 PAX6 PPP1R12C PRC1 PRPF6 RABGEF1 RB1 REL SAP30BP SF3B2 SNW1 TADA2A TFIP11 TRIM27 TRIM54 USHBP1 WDR77 ZMYND12	81 interacting genes: ACTN3 AIRIM ALOX15B ARHGEF28 ATP1A4 BAG6 BEX1 BEX2 BMF BORCS8 BORCS8-MEF2B C14orf119 CAMSAP1 CCDC116 CCHCR1 CDC37 CDKN2AIPNL CHCHD2 CSTF2T CTAG1A CYTH4 DESI1 FCHSD2 FSD2 GATC GNG13 GPSM3 GTF2I GUCD1 HCK HEMK1 HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 KIF26A KLHL38 LAMTOR1 LNPEP LONRF3 MAGEC1 MEIS2 MGAT5B MSGN1 NAB2 NCS1 NTAQ1 P4HA3 PEF1 PIH1D2 POLM PSMB1 RANBP10 REX1BD RSRC2 RTN4IP1 RUSC1 SEC14L4 SGTA SGTB SIKE1 SMG9 SOHLH1 SPAG8 STRA8 SUOX TCEANC TEPSIN THOC1 TNPO2 TRIB3 TRIM55 TRIM63 TSGA10IP UBE2V1 UBL5 UBQLN1 UBQLN2 USP20 VENTX WWOX
Entrez ID		9984	1485
HPRD ID		09498	02151
Ensembl ID		ENSG00000079134	ENSG00000184033
Uniprot IDs		Q96FV9	P78358
PDB IDs		1WXP 7APK 7ZNK 7ZNL	1S9W 2BNQ 2BNR 2F53 2F54 2P5E 2P5W 2PYE 3GJF 3HAE 3KLA 6AT5 6AVF 6AVG 6RP9 6RPA 6RPB 9C3E 9DL1
Enriched GO Terms of Interacting Partners?		MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Catalytic Step 2 Spliceosome Spliceosomal Complex RNA Metabolic Process RNA Splicing MRNA Processing MRNA Metabolic Process Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Processing Cyclin/CDK Positive Transcription Elongation Factor Complex U2-type Precatalytic Spliceosome	Protein Binding Peptide Antigen Assembly With MHC Class II Protein Complex MHC Class II Protein Complex Antigen Processing And Presentation Of Exogenous Peptide Antigen Positive Regulation Of ERAD Pathway Antigen Processing And Presentation Of Exogenous Antigen Regulation Of ERAD Pathway MHC Class II Protein Complex Binding ER To Golgi Transport Vesicle Membrane Lumenal Side Of Endoplasmic Reticulum Membrane Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Peptide Antigen Binding TRC Complex Positive Regulation Of Response To Endoplasmic Reticulum Stress Myeloid Dendritic Cell Antigen Processing And Presentation Transport Vesicle Membrane Antigen Processing And Presentation Trans-Golgi Network Membrane Skeletal Muscle Atrophy Dendritic Cell Antigen Processing And Presentation Positive Regulation Of Proteasomal Protein Catabolic Process Clathrin-coated Endocytic Vesicle Membrane Protein Targeting To ER Regulation Of Protein Ubiquitination Skeletal Muscle Adaptation Striated Muscle Atrophy Lysosomal Membrane Endocytic Vesicle Membrane Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Establishment Of Protein Localization To Endoplasmic Reticulum Autolysosome Membrane Muscle Atrophy Positive Regulation Of T Cell Mediated Immune Response To Tumor Cell MHC Class II Receptor Activity Polyubiquitin Modification-dependent Protein Binding Late Endosome Membrane Regulation Of Response To Endoplasmic Reticulum Stress ERAD Pathway Regulation Of Post-translational Protein Modification
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