PDE6D and RAB13

Number of citations of the paper that reports this interaction (PubMedID 9712853)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid, in vitro, in vivo)

		PDE6D	RAB13
Description		phosphodiesterase 6D	RAB13, member RAS oncogene family
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Cilium Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Cell Projection	Endosome Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Cell-cell Junction Bicellular Tight Junction Synaptic Vesicle Membrane Lateral Plasma Membrane Lamellipodium Cell Junction Endocytic Vesicle Trans-Golgi Network Transport Vesicle Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Insulin-responsive Compartment Cell Projection Neuron Projection Recycling Endosome Recycling Endosome Membrane Extracellular Exosome Anchoring Junction
	Molecular Function	GTPase Inhibitor Activity Protein Binding Small GTPase Binding	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Visual Perception Sensory Perception Of Light Stimulus	Exocytosis Golgi To Plasma Membrane Transport Intracellular Protein Localization Protein Kinase A Signaling Protein Transport Endosomal Transport Cortical Actin Cytoskeleton Organization Neuron Projection Development Endocytic Recycling Cellular Response To Insulin Stimulus Toll-like Receptor 4 Signaling Pathway Endothelial Cell Chemotaxis Trans-Golgi Network To Recycling Endosome Transport Localization Within Membrane Bicellular Tight Junction Assembly Protein Localization To Plasma Membrane Establishment Of Sertoli Cell Barrier Protein Localization To Cell Leading Edge
Pathways		ARL13B-mediated ciliary trafficking of INPP5E RAS processing	Translocation of SLC2A4 (GLUT4) to the plasma membrane RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Eating disorders (purging via substances) ( 23568457) Height ( 18391951)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cooked vegetable consumption ( 32066663) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		25 interacting genes: ARL15 ARL16 ARL2 ARL3 CDC42 CETN3 FAM219A GNAI1 GRK1 GRK7 HRAS OTP PTGIR RAB13 RAB18 RAB8A RAD23A RAP1A RAP2B RASA1 RHEB RHOA RHOB RND1 RPGR	10 interacting genes: APP MICALL1 PDE6D RAB11A RAB7A RAB8A RABGAP1L SMAD4 SMURF2 TGFBR1
Entrez ID		5147	5872
HPRD ID		04056	04053
Ensembl ID		ENSG00000156973	ENSG00000143545
Uniprot IDs		B8ZZK5 O43924 Q6IB24	A0A087WWB9 P51153 Q504R6
PDB IDs		1KSG 1KSH 1KSJ 3T5G 3T5I 4JHP 4JV6 4JV8 4JVB 4JVF 5E80 5E8F 5F2U 5ML2 5ML3 5ML4 5ML6 5ML8 5NAL 5TAR 5TB5 5X72 5X73 5X74 5YAV 5YAW 7PAC 7PAD 7PAE 7Q9Q 7Q9R 7Q9S 7Q9U 7QF9 7QJK
Enriched GO Terms of Interacting Partners?		GTPase Activity GTP Binding GDP Binding Nucleotide Binding Small GTPase-mediated Signal Transduction G Protein Activity Intracellular Signaling Cassette Ciliary Basal Body Intracellular Signal Transduction Mitotic Cytokinesis Midbody Rhodopsin Kinase Activity Regulation Of Cytoskeleton Organization Cytoskeleton-dependent Cytokinesis Centrosome Photoreceptor Connecting Cilium Hydrolase Activity Signal Transduction G Protein-coupled Receptor Kinase Activity Cellular Developmental Process Golgi Apparatus Extracellular Exosome Rap Protein Signal Transduction Regulation Of Opsin-mediated Signaling Pathway Protein Localization To Cilium Cell-cell Junction Organization Cytoskeleton Regulation Of Actin Cytoskeleton Organization Endothelial Tube Morphogenesis Regulation Of Actin Filament-based Process Regulation Of Modification Of Postsynaptic Structure Cellular Response To Forskolin Phagocytic Vesicle Regulation Of Cell-substrate Adhesion Establishment Of Epithelial Cell Apical/basal Polarity Response To Forskolin Trans-Golgi Network Transport Vesicle Protein Localization To Cell Periphery Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Regulation Of Modification Of Synaptic Structure Recycling Endosome Membrane Photoreceptor Disc Membrane Protein Kinase Binding Establishment Of Apical/basal Cell Polarity G-protein Beta/gamma-subunit Complex Binding Polarized Epithelial Cell Differentiation Establishment Of Monopolar Cell Polarity Actin Filament Organization Cell Junction Assembly Establishment Or Maintenance Of Monopolar Cell Polarity	Endosome Neurotransmitter Receptor Transport Endosome To Plasma Membrane Protein Transport Endocytic Recycling Cytoplasmic Vesicle Regulation Of Long-term Neuronal Synaptic Plasticity Small GTPase Binding Vesicle-mediated Transport To The Plasma Membrane Vesicle-mediated Transport SMAD Binding Regulation Of Neuronal Synaptic Plasticity Plasma Membrane Bounded Cell Projection Organization Establishment Of Protein Localization To Membrane Establishment Of Protein Localization To Plasma Membrane Protein Localization To Cilium Protein-containing Complex Localization Presynaptic Endosome Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Neurotransmitter Receptor Transport, Endosome To Plasma Membrane Positive Regulation Of Extracellular Matrix Assembly Endothelial Cell Activation Neurotransmitter Receptor Transport To Postsynaptic Membrane Endosomal Transport Phagocytic Vesicle Membrane Docking Establishment Of Protein Localization To Postsynaptic Membrane Protein Transport Neurotransmitter Receptor Transport To Plasma Membrane Cell Projection Organization Endosome Membrane Vesicle-mediated Transport In Synapse Recycling Endosome Membrane Intracellular Transport Trans-Golgi Network Membrane I-SMAD Binding Myosin V Binding Establishment Of Protein Localization Golgi Apparatus Recycling Endosome Regulation Of Extracellular Matrix Assembly Endocytosis Positive Regulation Of Extracellular Matrix Organization Centriole Cardiac Epithelial To Mesenchymal Transition Cellular Localization Establishment Of Localization In Cell Activin Receptor Signaling Pathway Neuron Projection Development Protein Localization To Postsynaptic Membrane Protein Localization To Postsynapse
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