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SLC23A1 and KRTAP10-8
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
SLC23A1
KRTAP10-8
Gene Name
solute carrier family 23 (ascorbic acid transporter), member 1
keratin associated protein 10-8
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Brush Border
Basal Plasma Membrane
Membrane
Apical Plasma Membrane
Intracellular Organelle
Extracellular Vesicular Exosome
Keratin Filament
Molecular Function
Protein Binding
L-ascorbate:sodium Symporter Activity
Sodium Ion Transmembrane Transporter Activity
Nucleobase Transmembrane Transporter Activity
L-ascorbic Acid Transporter Activity
Dehydroascorbic Acid Transporter Activity
Sodium-dependent L-ascorbate Transmembrane Transporter Activity
Biological Process
Nucleobase-containing Compound Metabolic Process
Vitamin Metabolic Process
Water-soluble Vitamin Metabolic Process
Sodium Ion Transport
Brain Development
Response To Toxic Substance
Nucleobase Transport
L-ascorbic Acid Transport
L-ascorbic Acid Metabolic Process
Lung Development
Vitamin Transmembrane Transport
Sodium Ion Transmembrane Transport
Small Molecule Metabolic Process
Dehydroascorbic Acid Transport
Transepithelial L-ascorbic Acid Transport
Pathways
Metabolism of vitamins and cofactors
Defective CD320 causes methylmalonic aciduria
Defective GIF causes intrinsic factor deficiency
Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF
Defective HLCS causes multiple carboxylase deficiency
Defective MMAB causes methylmalonic aciduria type cblB
Defective BTD causes biotidinase deficiency
Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC
Defective MTR causes methylmalonic aciduria and homocystinuria type cblG
Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD
Vitamin C (ascorbate) metabolism
Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE
Defective MMAA causes methylmalonic aciduria type cblA
Defective CUBN causes hereditary megaloblastic anemia 1
Defective AMN causes hereditary megaloblastic anemia 1
Defective MUT causes methylmalonic aciduria mut type
Metabolism of water-soluble vitamins and cofactors
Defects in biotin (Btn) metabolism
Defective TCN2 causes hereditary megaloblastic anemia
Defects in cobalamin (B12) metabolism
Defects in vitamin and cofactor metabolism
Drugs
Vitamin C
Diseases
GWAS
Protein-Protein Interactions
12 interactors:
ADAMTSL4
AHCYL1
KRT31
KRTAP10-1
KRTAP10-3
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP4-2
MTUS2
NOTCH2NL
163 interactors:
ACY3
ADAMTSL3
ADAMTSL4
AEN
AES
ALDH3B1
ALPI
APOL6
ASPSCR1
ATG9A
BEX2
BMP7
C11orf87
C19orf66
C9orf9
CARHSP1
CARKD
CATSPER1
CCDC26
CCNJL
CHIC2
CHRD
CHRNG
CLK4
CNNM3
COL8A1
CRCT1
CREB5
DAAM2
DCX
DDX55
DDX6
DERL2
DHRS1
DHX57
DMRT3
DOCK2
EIF4E2
FAH
FAM27E3
FAM74A4
FAM76B
FBXW5
FOXB1
GFOD1
GLIDR
GLP1R
GLRX3
GLYAT
GNAI2
GNE
GOLGA8EP
HHEX
HOXA1
HPCAL1
HSD3B7
HSPD1
IGSF8
ITGB5
JOSD1
KLHL38
KRT20
KRT83
KRTAP10-3
KRTAP10-7
KRTAP10-9
KRTAP12-1
KRTAP12-2
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-7
KRTAP5-6
KRTAP5-9
KRTAP9-2
KRTAP9-4
LCE1B
LCE2A
LCE2D
LCE3C
LCE3E
LCE4A
LINC00656
LOC153684
LRCH4
LUZP4
LYVE1
MAPKBP1
MATN3
MEOX2
MLLT6
MTA1
MXI1
NAB2
NOTCH2NL
NUFIP2
OTX1
P2RX7
PCED1A
PCSK5
PDE9A
PGLS
PIGS
PKD2
POM121L8P
PRKAB2
PRPF31
PRR13
PTGER3
PTPMT1
PTPRH
PVR
PVRL3
QPRT
R3HDM2
RANBP3
RPS28
RTN4RL1
SCNM1
SLC22A23
SLC23A1
SLC25A10
SLC6A20
SMCP
SMOC1
SPATA3
SPRY1
SPRY2
STK16
SUSD6
TBC1D16
TBC1D23
THAP10
THAP7
TMEM150A
TNIP3
TNP2
TNS2
TRPV6
TXNDC5
TYMSOS
TYRO3
UTP23
UXT
VPS11
WIF1
WT1
WT1-AS
YIPF3
ZBTB24
ZFYVE21
ZNF124
ZNF138
ZNF20
ZNF32
ZNF417
ZNF439
ZNF473
ZNF572
ZNF578
ZNF587
ZNF697
ZSCAN21
Entrez ID
9963
386681
HPRD ID
04810
11194
Ensembl ID
ENSG00000170482
ENSG00000187766
Uniprot IDs
Q9UHI7
P60410
PDB IDs
Enriched GO Terms of Interacting Partners
?
Keratinization
RNA Biosynthetic Process
Transcription, DNA-templated
Gene Expression
RNA Metabolic Process
Pattern Specification Process
Keratinocyte Differentiation
Organ Development
Epithelium Development
Cellular Nitrogen Compound Metabolic Process
Developmental Process
Nucleobase-containing Compound Metabolic Process
Nitrogen Compound Metabolic Process
Multicellular Organismal Development
Cellular Aromatic Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Epidermis Development
Tissue Development
Negative Regulation Of Glomerulus Development
Negative Regulation Of Glomerular Mesangial Cell Proliferation
Epidermal Cell Differentiation
Macromolecule Biosynthetic Process
Metanephric Mesenchyme Development
Heterocycle Metabolic Process
Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Sperm Motility
Negative Regulation Of Cell Proliferation Involved In Kidney Development
Fertilization
Biosynthetic Process
Anterior/posterior Pattern Specification
Anatomical Structure Development
Epithelial Cell Differentiation
Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Metanephric S-shaped Body Morphogenesis
Single Fertilization
System Development
Branching Morphogenesis Of An Epithelial Tube
Regulation Of Glomerular Mesangial Cell Proliferation
Penetration Of Zona Pellucida
S-shaped Body Morphogenesis
Positive Regulation Of Immune Response To Tumor Cell
Floor Plate Development
Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Tube Development
Skin Development
Bud Elongation Involved In Lung Branching
Morphogenesis Of A Branching Epithelium
Negative Regulation Of Mesenchymal Cell Apoptotic Process
Epithelial Tube Branching Involved In Lung Morphogenesis
Morphogenesis Of A Branching Structure
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Tagcloud (Difference)
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Tagcloud (Intersection)
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