Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
SLC23A1 and NOTCH2NL
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
SLC23A1
NOTCH2NL
Gene Name
solute carrier family 23 (ascorbic acid transporter), member 1
notch 2 N-terminal like
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Brush Border
Basal Plasma Membrane
Membrane
Apical Plasma Membrane
Intracellular Organelle
Extracellular Vesicular Exosome
Extracellular Region
Cytoplasm
Molecular Function
Protein Binding
L-ascorbate:sodium Symporter Activity
Sodium Ion Transmembrane Transporter Activity
Nucleobase Transmembrane Transporter Activity
L-ascorbic Acid Transporter Activity
Dehydroascorbic Acid Transporter Activity
Sodium-dependent L-ascorbate Transmembrane Transporter Activity
Calcium Ion Binding
Biological Process
Nucleobase-containing Compound Metabolic Process
Vitamin Metabolic Process
Water-soluble Vitamin Metabolic Process
Sodium Ion Transport
Brain Development
Response To Toxic Substance
Nucleobase Transport
L-ascorbic Acid Transport
L-ascorbic Acid Metabolic Process
Lung Development
Vitamin Transmembrane Transport
Sodium Ion Transmembrane Transport
Small Molecule Metabolic Process
Dehydroascorbic Acid Transport
Transepithelial L-ascorbic Acid Transport
Notch Signaling Pathway
Multicellular Organismal Development
Cell Differentiation
Pathways
Metabolism of vitamins and cofactors
Defective CD320 causes methylmalonic aciduria
Defective GIF causes intrinsic factor deficiency
Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF
Defective HLCS causes multiple carboxylase deficiency
Defective MMAB causes methylmalonic aciduria type cblB
Defective BTD causes biotidinase deficiency
Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC
Defective MTR causes methylmalonic aciduria and homocystinuria type cblG
Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD
Vitamin C (ascorbate) metabolism
Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE
Defective MMAA causes methylmalonic aciduria type cblA
Defective CUBN causes hereditary megaloblastic anemia 1
Defective AMN causes hereditary megaloblastic anemia 1
Defective MUT causes methylmalonic aciduria mut type
Metabolism of water-soluble vitamins and cofactors
Defects in biotin (Btn) metabolism
Defective TCN2 causes hereditary megaloblastic anemia
Defects in cobalamin (B12) metabolism
Defects in vitamin and cofactor metabolism
Drugs
Vitamin C
Diseases
GWAS
Protein-Protein Interactions
12 interactors:
ADAMTSL4
AHCYL1
KRT31
KRTAP10-1
KRTAP10-3
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP4-2
MTUS2
NOTCH2NL
241 interactors:
ACY3
ADAMTSL3
ADAMTSL5
ADCK5
AES
ALDH3B1
ALPI
AQP1
AQP5
ARID3A
ASPSCR1
ATG9A
BCL6B
BLCAP
BMP7
C11orf87
C16orf59
C19orf66
C5orf60
CA6
CARHSP1
CARKD
CATSPER1
CCDC26
CCDC93
CCER1
CD164
CDK5R1
CERK
CHCHD3
CHDH
CHIC2
CHRD
CHRNG
CLDN2
CLEC18A
COL8A1
CRACR2A
CRCT1
CREB5
CSF1
CST2
CST9L
CTSG
CTSZ
CXCL16
CXCL5
DGCR6
DHRS1
DMRT3
DNAL4
DOCK2
EFNA3
EIF4E2
ELANE
EPHB6
ESR2
FAAH
FAM124B
FAM71C
FAM71E2
FAM74A4
FARS2
FASLG
FBXL18
FBXW5
FOXB1
FRS3
GABRD
GATA2
GEM
GFOD1
GIP
GLP1R
GLRX3
GLYAT
GNAI2
GNE
GNMT
GSTP1
GTF3C5
HBZ
HCK
HIST1H2AK
HOXA1
HPCAL1
HSBP1
HSD3B7
HSPA12B
HSPBP1
HSPD1
ICAM4
IFI30
IL2RG
INPP5D
ITGB2
ITGB5
JOSD1
KCTD15
KIF1A
KLHL38
KLK8
KRT20
KRT83
KRTAP10-1
KRTAP10-11
KRTAP10-3
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP12-2
KRTAP12-4
KRTAP13-3
KRTAP26-1
KRTAP3-1
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-7
KRTAP5-6
KRTAP5-9
KRTAP9-2
KRTAP9-4
LCE1B
LCE2D
LCE3C
LCE3E
LIMS2
LIN7A
LINC00526
LINC00656
LMO2
LNX1
LONRF3
LRCH4
LRFN4
MAPKBP1
MARK4
MATN3
MFI2
MRGBP
MRPL40
MTA1
MVP
MXD3
MXI1
NAB2
NEU2
NMU
NMUR2
NPBWR2
NPDC1
NPPB
NR1D2
NUBP2
P2RX4
PCED1A
PCED1B
PCSK5
PDE9A
PGLS
PID1
PIGS
PLSCR4
POLR2G
POM121L8P
POMGNT2
PPAP2C
PRKAA2
PRPF31
PRPS2
PSMA1
PSMG2
PTGER3
PTPMT1
PTPN23
PVR
PVRL2
PVRL3
QPRT
R3HDM2
RAB3IL1
RAMP3
RCHY1
RECK
RET
RGL2
RPS28
RTN4RL1
SCNM1
SDCBP
SELM
SEMA4C
SLC22A23
SLC23A1
SLC25A10
SLC25A6
SLC6A20
SMARCD2
SMARCE1
SMCP
SMOC1
SNAI1
SPATA8
SPG7
SPINK2
SPRY1
STK16
TBC1D10C
TBC1D16
THAP7
THEMIS2
TINAGL1
TMEM150A
TMEM231
TMEM41A
TNIP3
TNK2
TNP2
TRIM27
TRIM42
TRPV6
TSPAN4
TXNDC5
UBQLN4
UTP23
UXT
WDR25
WT1-AS
XCL2
YIPF3
ZFYVE21
ZNF124
ZNF32
ZNF417
ZNF439
ZNF440
ZNF446
ZNF581
ZNF587
Entrez ID
9963
388677
HPRD ID
04810
14833
Ensembl ID
ENSG00000170482
ENSG00000213240
Uniprot IDs
Q9UHI7
Q7Z3S9
PDB IDs
Enriched GO Terms of Interacting Partners
?
Developmental Process
Anatomical Structure Development
Negative Regulation Of Cellular Metabolic Process
Locomotion
Negative Regulation Of Biosynthetic Process
Multicellular Organismal Development
Response To Lipid
Cell Motility
Cellular Response To Lipid
Movement Of Cell Or Subcellular Component
Response To Lipopolysaccharide
Positive Regulation Of Immune Response To Tumor Cell
RNA Biosynthetic Process
Transcription, DNA-templated
System Development
Response To Molecule Of Bacterial Origin
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Response To External Stimulus
Susceptibility To T Cell Mediated Cytotoxicity
Formation Of Primary Germ Layer
Cellular Response To Stimulus
Cellular Process
Negative Regulation Of Transcription, DNA-templated
Regulation Of Systemic Arterial Blood Pressure By Circulatory Renin-angiotensin
Regulation Of Protein Metabolic Process
Biosynthetic Process
Endodermal Cell Differentiation
Cell Migration
Regulation Of Metabolic Process
Regulation Of Cellular Process
Response To Stimulus
Gene Expression
Nitrogen Compound Metabolic Process
Organ Development
Keratinization
Anatomical Structure Morphogenesis
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of Gene Expression
Enzyme Linked Receptor Protein Signaling Pathway
Regulation Of Cellular Protein Metabolic Process
Neutrophil Mediated Immunity
Extracellular Matrix Organization
Extracellular Structure Organization
Susceptibility To Natural Killer Cell Mediated Cytotoxicity
Carbon Dioxide Transport
Gastrulation
Cellular Macromolecule Biosynthetic Process
Tissue Development
Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin
Tagcloud
?
a3
a3s
a465tmutation
anaplastic
astrocytoma
atrx
challenging
diffuse
distinguish
exome
gbm
gbms
glioblastoma
gliomas
grade
idh1
illuminate
landscape
lethal
multiforme
oa2
oa3
oligoastrocytoma
sequenced
signatures
Tagcloud (Difference)
?
a3
a3s
a465tmutation
anaplastic
astrocytoma
atrx
challenging
diffuse
distinguish
exome
gbm
gbms
glioblastoma
gliomas
grade
idh1
illuminate
landscape
lethal
multiforme
oa2
oa3
oligoastrocytoma
sequenced
signatures
Tagcloud (Intersection)
?