SLC23A1 and AHCYL1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC23A1	AHCYL1
Description		solute carrier family 23 member 1	adenosylhomocysteinase like 1
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GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Basal Plasma Membrane Membrane Apical Plasma Membrane Intracellular Organelle Extracellular Exosome	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Apical Plasma Membrane Intracellular Membrane-bounded Organelle Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site Extracellular Exosome
	Molecular Function	Protein Binding L-ascorbate:sodium Symporter Activity Sodium Ion Transmembrane Transporter Activity Urate Transmembrane Transporter Activity Nucleobase Transmembrane Transporter Activity L-ascorbic Acid Transmembrane Transporter Activity Symporter Activity Transmembrane Transporter Activity Dehydroascorbic Acid Transmembrane Transporter Activity	RNA Binding Adenosylhomocysteinase Activity Protein Binding Enzyme Regulator Activity Identical Protein Binding
	Biological Process	Monoatomic Ion Transport Sodium Ion Transport Brain Development Response To Toxic Substance Urate Transport Nucleobase Transport L-ascorbic Acid Transmembrane Transport L-ascorbic Acid Metabolic Process Lung Development Sodium Ion Transmembrane Transport Transmembrane Transport Dehydroascorbic Acid Transport	Protein Export From Nucleus One-carbon Metabolic Process Apoptotic Process Positive Regulation Of Sodium Ion Transport Regulation Of MRNA 3'-end Processing Regulation Of Monoatomic Ion Transmembrane Transporter Activity S-adenosylmethionine Cycle Angiotensin-activated Signaling Pathway Epithelial Fluid Transport Regulation Of Monoatomic Anion Transport Response To Calcium Ion Mitochondrion-endoplasmic Reticulum Membrane Tethering
Pathways		Vitamin C (ascorbate) metabolism	PLC beta mediated events DAG and IP3 signaling Role of phospholipids in phagocytosis FCERI mediated Ca+2 mobilization Regulation of insulin secretion VEGFR2 mediated cell proliferation Ion homeostasis Ion homeostasis CLEC7A (Dectin-1) induces NFAT activation FCGR3A-mediated IL10 synthesis Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Drugs
Diseases
GWAS		Body mass index ( 26426971) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Malaria ( 31844061) Vitamin C levels ( 33203707)	Height ( 31562340)
Interacting Genes		24 interacting genes: ADAMTSL4 AHCYL1 CYSRT1 EFEMP2 HOXA1 KRT31 KRT34 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP4-11 KRTAP4-2 KRTAP9-3 MEOX2 MTUS2 NBPF19 NOTCH2NLA	25 interacting genes: BID BTG3 CDKN2C CFTR DACH1 GEM HBQ1 HGS HSPA6 ITPR1 LRRK2 MEOX2 MFHAS1 PLEKHG5 PPL PRDM6 PSMD9 RNF6 SLC23A1 SOX30 SRPK1 SRPK2 SUMO2 UACA ZNF165
Entrez ID		9963	10768
HPRD ID		04810	07613
Ensembl ID		ENSG00000170482	ENSG00000168710
Uniprot IDs		Q9UHI7	A0A024R0A8 O43865
PDB IDs		8JEW 8JEZ 8JF0 8JF1	3MTG
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament Structural Constituent Of Skin Epidermis Identical Protein Binding Intermediate Filament Organization Hair Cycle Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Cytosol Epidermis Development Semicircular Canal Formation Positive Regulation Of Smooth Muscle Cell-matrix Adhesion Pigment Cell Development Artery Development Structural Molecule Activity Abducens Nerve Formation Optokinetic Behavior Tissue Morphogenesis Adenosylhomocysteinase Activity Positive Regulation Of Aortic Smooth Muscle Cell Differentiation
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