SLC23A1 and KRTAP12-3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC23A1	KRTAP12-3
Description		solute carrier family 23 member 1	keratin associated protein 12-3
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Basal Plasma Membrane Membrane Apical Plasma Membrane Intracellular Organelle Extracellular Exosome	Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Protein Binding L-ascorbate:sodium Symporter Activity Sodium Ion Transmembrane Transporter Activity Urate Transmembrane Transporter Activity Nucleobase Transmembrane Transporter Activity L-ascorbic Acid Transmembrane Transporter Activity Symporter Activity Transmembrane Transporter Activity Dehydroascorbic Acid Transmembrane Transporter Activity	Protein Binding Identical Protein Binding
	Biological Process	Monoatomic Ion Transport Sodium Ion Transport Brain Development Response To Toxic Substance Urate Transport Nucleobase Transport L-ascorbic Acid Transmembrane Transport L-ascorbic Acid Metabolic Process Lung Development Sodium Ion Transmembrane Transport Transmembrane Transport Dehydroascorbic Acid Transport
Pathways		Vitamin C (ascorbate) metabolism	Keratinization
Drugs
Diseases
GWAS		Body mass index ( 26426971) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Malaria ( 31844061) Vitamin C levels ( 33203707)
Interacting Genes		24 interacting genes: ADAMTSL4 AHCYL1 CYSRT1 EFEMP2 HOXA1 KRT31 KRT34 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP4-11 KRTAP4-2 KRTAP9-3 MEOX2 MTUS2 NBPF19 NOTCH2NLA	145 interacting genes: ADAMTSL3 ADAMTSL4 AGXT ALDH3B1 BCL6B BMP7 C11orf87 C22orf39 CARD10 CATSPER1 CBX2 CELF5 CHIC2 CHRD CHRNG CNNM3 COL8A1 CRCT1 CREB5 CYSRT1 DALRD3 DHRS1 DHX57 DNAL4 DOCK2 FASLG FBXW5 GLRX3 GNE GTF3C5 HOXA1 ITGB4 JOSD1 KPRP KRT20 KRTAP1-1 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP13-1 KRTAP13-2 KRTAP13-3 KRTAP19-7 KRTAP3-3 KRTAP4-2 KRTAP4-4 KRTAP5-6 KRTAP5-9 KRTAP6-1 KRTAP6-2 KRTAP9-2 KRTAP9-3 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3C LCE3D LCE3E LCE4A LCE5A LIF LMNTD2 LNX1 LYVE1 MAPKBP1 MEOX2 MISP MOBP NBPF19 NKD1 NMU NOTCH2NLA NPDC1 NR1D2 NR4A3 NUFIP2 OTX1 OXER1 P2RX4 P2RY6 P3H3 P4HB PDE9A PDGFRB PGAP6 PHLDA1 POU4F2 PTGDS PTPMT1 R3HDM2 RSPO2 SELENOM SHFL SLC13A5 SLC15A2 SLC23A1 SMCP SPATA3 SPRY1 TCEA2 TCEANC TFAP2D TMIE TNP2 TNS2 TTPA UTP23 UXT VASN VGLL3 VSTM4 WDR25 WNT11 YY1 ZDHHC1 ZNF101 ZNF124 ZNF138 ZNF20 ZNF408 ZNF417 ZNF439 ZNF440 ZNF467 ZNF490 ZNF491 ZNF497 ZNF578 ZNF587 ZNF648 ZNF696 ZNF80 ZNF835 ZNF837 ZSCAN21
Entrez ID		9963	386683
HPRD ID		04810	11199
Ensembl ID		ENSG00000170482	ENSG00000205439
Uniprot IDs		Q9UHI7	P60328
PDB IDs		8JEW 8JEZ 8JF0 8JF1
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament Structural Constituent Of Skin Epidermis Identical Protein Binding Intermediate Filament Organization Hair Cycle Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Cytosol Epidermis Development Semicircular Canal Formation Positive Regulation Of Smooth Muscle Cell-matrix Adhesion Pigment Cell Development Artery Development Structural Molecule Activity Abducens Nerve Formation Optokinetic Behavior Tissue Morphogenesis Adenosylhomocysteinase Activity Positive Regulation Of Aortic Smooth Muscle Cell Differentiation	Keratinization Intermediate Filament Epidermis Development Keratin Filament Protein Binding Tissue Development DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Regulation Of Transcription By RNA Polymerase II Identical Protein Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
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