CDC25A and CHEK1

  • Number of citations of the paper that reports this interaction (PMID 12676583)
  • 109
  • Data Source:
  • HPRD (in vitro, in vivo)

CDC25A

CHEK1

Gene Name cell division cycle 25A checkpoint kinase 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 52 interactors: ANAPC11 APP AR BTRC CAMK1D CCNA1 CCNB1 CCNE1 CCNI CDK1 CDK2 CDKN3 CHEK1 CHEK2 CSNK1A1 CUL3 CUX1 DMD DUSP8 EEF1A1 EGFR FAM193B FBXW11 FGF21 FTH1 FZR1 HLA-C HRAS IL3RA LMO2 MAP3K5 MAPK14 MCM3AP MTAP NAA10 NFKBIB NFYA PEX19 PIM1 POLR1D RAF1 ROCK1 SCYL1 SMAD3 SOX5 UBB VAMP8 XPO1 YWHAB YWHAE YWHAQ YWHAZ 37 interactors: AATF AKT1 APP ATM ATR BLM BRCA1 CDC25A CDC25B CDC25C CHUK CLSPN CSNK2B CUL1 CUL4A DTL FANCE HSP90AA1 LATS2 MCPH1 MDM4 PIGM PRKDC RAD51 RB1 RELA SMAD4 TIMELESS TLK1 TOPBP1 TP53 UBB USP7 XIAP XPO1 XRCC6 YWHAG
Entrez ID 993 1111
HPRD ID 00305 04356
Ensembl ID ENSG00000164045 ENSG00000149554
Uniprot IDs P30304 B4DT73 O14757
PDB IDs 1C25 1IA8 1NVQ 1NVR 1NVS 1ZLT 1ZYS 2AYP 2BR1 2BRB 2BRG 2BRH 2BRM 2BRN 2BRO 2C3J 2C3K 2C3L 2CGU 2CGV 2CGW 2CGX 2E9N 2E9O 2E9P 2E9U 2E9V 2GDO 2GHG 2HOG 2HXL 2HXQ 2HY0 2QHM 2QHN 2R0U 2WMQ 2WMR 2WMS 2WMT 2WMU 2WMV 2WMW 2WMX 2X8D 2X8E 2X8I 2XEY 2XEZ 2XF0 2YDI 2YDJ 2YDK 2YER 2YEX 2YM3 2YM4 2YM5 2YM6 2YM7 2YM8 2YWP 3F9N 3JVR 3JVS 3NLB 3OT3 3OT8 3PA3 3PA4 3PA5 3TKH 3TKI 3U9N 4FSM 4FSN 4FSQ 4FSR 4FST 4FSU 4FSW 4FSY 4FSZ 4FT0 4FT3 4FT5 4FT7 4FT9 4FTA 4FTC 4FTI 4FTJ 4FTK 4FTL 4FTM 4FTN 4FTO 4FTQ 4FTR 4FTT 4FTU 4GH2 4HYH 4HYI 4JIK
Enriched GO Terms of Interacting Partners?
Tagcloud ?
a2  abstract  adenosine  analog  arrest  blocks  cdk2  chk2  contributes  cordycepin  cordyceps  cytochrome  cytosol  erk1  exert  inhibits  initiates  intrinsic  involves  leads  militaris  mitochondria  nb  obscure  released  sensitizes  trigger  u937  ways 
aggressive  atr  bcss  clinically  consequences  cytoplasmic  deregulated  doxycycline  knock  lymphovascular  mb  mcf10a  mcf7  mda  mitotic  personalized  phenotypes  pleomorphism  positivity  predictor  rational  restored  ser345  serine345  signalling  tumorigenic  univariate  ve 
Tagcloud (Difference) ?
a2  abstract  adenosine  analog  arrest  blocks  cdk2  chk2  contributes  cordycepin  cordyceps  cytochrome  cytosol  erk1  exert  inhibits  initiates  intrinsic  involves  leads  militaris  mitochondria  nb  obscure  released  sensitizes  trigger  u937  ways 
aggressive  atr  bcss  clinically  consequences  cytoplasmic  deregulated  doxycycline  knock  lymphovascular  mb  mcf10a  mcf7  mda  mitotic  personalized  phenotypes  pleomorphism  positivity  predictor  rational  restored  ser345  serine345  signalling  tumorigenic  univariate  ve 
Tagcloud (Intersection) ?