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CDC25A and FAM193B
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
CDC25A
FAM193B
Gene Name
cell division cycle 25A
family with sequence similarity 193, member B
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytosol
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Molecular Function
Protein Tyrosine Phosphatase Activity
Protein Binding
Protein Kinase Binding
Biological Process
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
G1/S Transition Of Mitotic Cell Cycle
G2/M Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
DNA Replication
Mitotic Nuclear Division
Cell Proliferation
Response To Radiation
Cellular Response To UV
Peptidyl-tyrosine Dephosphorylation
Cell Division
Regulation Of Cell Cycle
Pathways
E2F mediated regulation of DNA replication
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
G2/M Checkpoints
G2/M Transition
G0 and Early G1
Cyclin E associated events during G1/S transition
S Phase
Cyclin B2 mediated events
Cell Cycle, Mitotic
Cyclin A/B1 associated events during G2/M transition
G1/S Transition
Activation of ATR in response to replication stress
G1/S-Specific Transcription
E2F-enabled inhibition of pre-replication complex formation
p53-Independent DNA Damage Response
Cell Cycle Checkpoints
Cyclin A:Cdk2-associated events at S phase entry
p53-Independent G1/S DNA damage checkpoint
Mitotic G2-G2/M phases
Mitotic G1-G1/S phases
Polo-like kinase mediated events
G1/S DNA Damage Checkpoints
Drugs
Diseases
GWAS
Protein-Protein Interactions
52 interactors:
ANAPC11
APP
AR
BTRC
CAMK1D
CCNA1
CCNB1
CCNE1
CCNI
CDK1
CDK2
CDKN3
CHEK1
CHEK2
CSNK1A1
CUL3
CUX1
DMD
DUSP8
EEF1A1
EGFR
FAM193B
FBXW11
FGF21
FTH1
FZR1
HLA-C
HRAS
IL3RA
LMO2
MAP3K5
MAPK14
MCM3AP
MTAP
NAA10
NFKBIB
NFYA
PEX19
PIM1
POLR1D
RAF1
ROCK1
SCYL1
SMAD3
SOX5
UBB
VAMP8
XPO1
YWHAB
YWHAE
YWHAQ
YWHAZ
10 interactors:
ATXN1
CDC25A
GOLGA2
GSK3A
GSK3B
LDOC1
MAPK8
PKN2
TRIM23
TRIM27
Entrez ID
993
54540
HPRD ID
00305
07671
Ensembl ID
ENSG00000164045
ENSG00000146067
Uniprot IDs
P30304
Q6IPW0
PDB IDs
1C25
Enriched GO Terms of Interacting Partners
?
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Mitotic Cell Cycle
Mitotic Cell Cycle Process
Regulation Of Protein Metabolic Process
Cell Cycle Process
Regulation Of Cell Cycle
Cell Cycle
Regulation Of Cellular Protein Metabolic Process
G2/M Transition Of Mitotic Cell Cycle
Regulation Of Mitotic Cell Cycle
Positive Regulation Of Cellular Metabolic Process
Regulation Of Phosphorus Metabolic Process
Regulation Of Phosphorylation
G1/S Transition Of Mitotic Cell Cycle
Regulation Of Protein Kinase Activity
Regulation Of Protein Phosphorylation
Regulation Of Kinase Activity
Regulation Of Metabolic Process
Positive Regulation Of Metabolic Process
Positive Regulation Of Proteolysis
Positive Regulation Of Protein Metabolic Process
Phosphorylation
Cellular Response To Organic Substance
Positive Regulation Of Cellular Protein Metabolic Process
Regulation Of Intracellular Transport
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Apoptotic Process
Regulation Of Cellular Component Organization
Positive Regulation Of Transferase Activity
Positive Regulation Of Gene Expression
Apoptotic Signaling Pathway
Programmed Cell Death
Cellular Response To Growth Factor Stimulus
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Response To Growth Factor
Cell Death
Death
Regulation Of Gene Expression
Regulation Of Protein Catabolic Process
Phosphate-containing Compound Metabolic Process
Protein Phosphorylation
Regulation Of Catalytic Activity
Response To Stimulus
Negative Regulation Of Mitotic Cell Cycle
Positive Regulation Of Transcription, DNA-templated
Regulation Of Ubiquitin-protein Transferase Activity
Cellular Protein Modification Process
Negative Regulation Of Type B Pancreatic Cell Development
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Hypermethylation Of CpG Island
Cellular Response To Interleukin-3
Negative Regulation Of Protein Binding
Positive Regulation Of Mitochondrion Organization
Negative Regulation Of Glycogen (starch) Synthase Activity
Regulation Of Mitochondrion Organization
Negative Regulation Of Cardiac Muscle Hypertrophy
Negative Regulation Of Glycogen Biosynthetic Process
Negative Regulation Of Muscle Hypertrophy
Regulation Of Glycogen (starch) Synthase Activity
Negative Regulation Of Binding
Positive Regulation Of Organelle Organization
Regulation Of Type B Pancreatic Cell Development
Positive Regulation Of Peptidyl-threonine Phosphorylation
Regulation Of Protein Binding
Regulation Of DNA Methylation
Regulation Of Gene Expression By Genetic Imprinting
Positive Regulation Of Apoptotic Signaling Pathway
Regulation Of Cardiac Muscle Hypertrophy
Response To Lithium Ion
Cellular Protein Modification Process
Regulation Of Gene Expression, Epigenetic
Regulation Of Glycogen Biosynthetic Process
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Genetic Imprinting
Negative Regulation Of Epithelial Cell Differentiation
Fc-epsilon Receptor Signaling Pathway
Regulation Of Phosphorylation
Protein Phosphorylation
Positive Regulation Of Intracellular Transport
Regulation Of Glycogen Metabolic Process
Regulation Of Binding
Regulation Of Catalytic Activity
Fc Receptor Signaling Pathway
Regulation Of Protein Kinase Activity
Regulation Of Phosphorus Metabolic Process
Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Regulation Of Kinase Activity
Negative Regulation Of Transferase Activity
Innate Immune Response
Response To Metal Ion
Glycogen Metabolic Process
Regulation Of Immune Response
Response To Light Stimulus
Apoptotic Signaling Pathway
Regulation Of Organelle Organization
Tagcloud
?
a2
abstract
adenosine
analog
arrest
blocks
cdk2
chk2
contributes
cordycepin
cordyceps
cytochrome
cytosol
erk1
exert
inhibits
initiates
intrinsic
involves
leads
militaris
mitochondria
nb
obscure
released
sensitizes
trigger
u937
ways
Tagcloud (Difference)
?
a2
abstract
adenosine
analog
arrest
blocks
cdk2
chk2
contributes
cordycepin
cordyceps
cytochrome
cytosol
erk1
exert
inhibits
initiates
intrinsic
involves
leads
militaris
mitochondria
nb
obscure
released
sensitizes
trigger
u937
ways
Tagcloud (Intersection)
?