CEP350 and PLEKHA5

Number of citations of the paper that reports this interaction (PMID 20936779)
48

Data Source:
BioGRID (two hybrid)

		CEP350	PLEKHA5
Gene Name		centrosomal protein 350kDa	pleckstrin homology domain containing, family A member 5
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Centrosome Spindle Membrane	Cytosol Membrane
	Molecular Function	Protein Binding Microtubule Binding	Protein Binding 1-phosphatidylinositol Binding Phosphatidylinositol-5-phosphate Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-4-phosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding
	Biological Process	Microtubule Anchoring	Biological_process Reproductive System Development
Pathways
Drugs
Diseases
GWAS		Anorexia nervosa ( 23568457)
Protein-Protein Interactions		6 interactors: APTX NR1H3 PLEKHA5 PPARA PPARD PPARG	30 interactors: ARHGEF9 BLOC1S6 CCDC186 CCDC88B CCDC92 CEP250 CEP350 DES EVPL EXTL3 KANSL1 KIF3A KRT19 KRT20 KTN1 LAMB2 LSM4 MAX PDZD11 PLEC PLEKHA6 PPP1R13B PROM1 SH3BP5L SOGA1 SPTAN1 SPTBN1 UPF1 WASH2P YWHAG
Entrez ID		9857	54477
HPRD ID		09870	09684
Ensembl ID		ENSG00000135837	ENSG00000052126
Uniprot IDs		Q5VT06	Q9HAU0
PDB IDs		2COZ	2DKP
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cholesterol Storage Steroid Hormone Mediated Signaling Pathway Negative Regulation Of Macrophage Derived Foam Cell Differentiation Regulation Of Receptor Biosynthetic Process Negative Regulation Of Lipid Storage Hormone-mediated Signaling Pathway Positive Regulation Of Fatty Acid Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Steroid Hormone Stimulus Intracellular Receptor Signaling Pathway DNA-templated Transcription, Initiation Regulation Of Macrophage Derived Foam Cell Differentiation Regulation Of Lipid Storage Fatty Acid Transport Negative Regulation Of Collagen Biosynthetic Process Negative Regulation Of Receptor Biosynthetic Process Negative Regulation Of Interferon-gamma-mediated Signaling Pathway Regulation Of Fatty Acid Metabolic Process Negative Regulation Of Multicellular Organismal Metabolic Process Cellular Response To Organic Cyclic Compound Regulation Of Lipid Transport Negative Regulation Of Sequestering Of Triglyceride Regulation Of Circadian Rhythm Cellular Response To Lipid Negative Regulation Of Inflammatory Response Response To Steroid Hormone Monocarboxylic Acid Transport Positive Regulation Of Fatty Acid Oxidation Cellular Response To Hormone Stimulus Regulation Of Interferon-gamma-mediated Signaling Pathway Regulation Of Response To Interferon-gamma Negative Regulation Of Transcription From RNA Polymerase II Promoter Response To Vitamin A Regulation Of Fatty Acid Oxidation Response To Lipid Transcription From RNA Polymerase II Promoter Response To Organic Cyclic Compound Regulation Of Inflammatory Response Regulation Of Collagen Metabolic Process Response To Hormone Regulation Of Cholesterol Transport Negative Regulation Of Innate Immune Response Negative Regulation Of Cytokine-mediated Signaling Pathway Regulation Of Lipid Metabolic Process Cellular Lipid Metabolic Process Lipid Transport Carboxylic Acid Transport Organic Acid Transport Negative Regulation Of Response To Cytokine Stimulus Fatty Acid Metabolic Process	Apoptotic Process Programmed Cell Death Cell Death Death Hemidesmosome Assembly Glomerular Visceral Epithelial Cell Differentiation Regulation Of Protein Complex Disassembly Cellular Localization Regulation Of Cellular Component Organization Movement Of Cell Or Subcellular Component Cellular Process Retina Development In Camera-type Eye Organelle Organization Generation Of Neurons Cell Differentiation Involved In Kidney Development Neuron Differentiation Cytoskeleton Organization Regulation Of Actin Filament Polymerization Microtubule-based Process Neurogenesis Metanephric Glomerular Basement Membrane Development Axon Extension Involved In Regeneration Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Cell-substrate Junction Assembly Actin Filament Capping Membrane Organization Regulation Of Cytoskeleton Organization Glomerulus Development Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Negative Regulation Of Actin Filament Depolymerization Epithelial Cell Differentiation Regulation Of Organelle Organization Metanephric Glomerular Visceral Epithelial Cell Development Response To Axon Injury Protein Localization Neuron Development Regulation Of Actin Filament Depolymerization Execution Phase Of Apoptosis Negative Regulation Of Actin Filament Polymerization Sensory Organ Development Glomerular Parietal Epithelial Cell Differentiation Positive Regulation Of Nephron Tubule Epithelial Cell Differentiation Regulation Of Centriole-centriole Cohesion Response To Insulin Establishment Of Localization In Cell Microtubule-based Movement Intracellular Transport Negative Regulation Of Protein Polymerization Post-Golgi Vesicle-mediated Transport
Tagcloud ?			a375 a375br a375p aberrantly barrier bbb brain cerebrotropic constructed differentially extra homing immunofluorescence knock mediators melanoma metastases metastasis metastatic overwhelming parental passage profiles profiling propensity subjected transmigration viability yumul
Tagcloud (Difference) ?			a375 a375br a375p aberrantly barrier bbb brain cerebrotropic constructed differentially extra homing immunofluorescence knock mediators melanoma metastases metastasis metastatic overwhelming parental passage profiles profiling propensity subjected transmigration viability yumul
Tagcloud (Intersection) ?