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CEP350 and NR1H3
Number of citations of the paper that reports this interaction (PMID
15615782
)
6
Data Source:
BioGRID
(pull down)
CEP350
NR1H3
Gene Name
centrosomal protein 350kDa
nuclear receptor subfamily 1, group H, member 3
Image
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Centrosome
Spindle
Membrane
Nuclear Chromatin
Nucleus
Nucleoplasm
Receptor Complex
RNA Polymerase II Transcription Factor Complex
Molecular Function
Protein Binding
Microtubule Binding
DNA Binding
Steroid Hormone Receptor Activity
Transcription Coactivator Activity
Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity
Protein Binding
Zinc Ion Binding
Cholesterol Binding
Sterol Response Element Binding
Sequence-specific DNA Binding
Transcription Regulatory Region DNA Binding
Biological Process
Microtubule Anchoring
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Gene Expression
Negative Regulation Of Macrophage Derived Foam Cell Differentiation
Positive Regulation Of Triglyceride Biosynthetic Process
Positive Regulation Of Receptor Biosynthetic Process
Positive Regulation Of Cholesterol Efflux
Negative Regulation Of Cholesterol Storage
Intracellular Receptor Signaling Pathway
Positive Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Lipid Transport
Positive Regulation Of Cholesterol Transport
Response To Progesterone
Positive Regulation Of Toll-like Receptor 4 Signaling Pathway
Cholesterol Homeostasis
Regulation Of Circadian Rhythm
Negative Regulation Of Macrophage Activation
Apoptotic Cell Clearance
Steroid Hormone Mediated Signaling Pathway
Positive Regulation Of Fatty Acid Biosynthetic Process
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Pinocytosis
Negative Regulation Of Inflammatory Response
Positive Regulation Of Lipoprotein Lipase Activity
Lipid Homeostasis
Sterol Homeostasis
Negative Regulation Of Interferon-gamma-mediated Signaling Pathway
Triglyceride Homeostasis
Cellular Response To Lipopolysaccharide
Negative Regulation Of Pancreatic Juice Secretion
Negative Regulation Of Secretion Of Lysosomal Enzymes
Regulation Of Cholesterol Homeostasis
Positive Regulation Of Cholesterol Homeostasis
Pathways
Drugs
Diseases
GWAS
Anorexia nervosa (
23568457
)
HDL cholesterol (
19060910
20686565
)
Metabolic syndrome (
22399527
)
Protein-Protein Interactions
6 interactors:
APTX
NR1H3
PLEKHA5
PPARA
PPARD
PPARG
30 interactors:
ACTN1
APP
CEP350
EDF1
EIF3I
FOXO3
ING3
KAT2B
KDM1A
LZTR1
MDFI
MSTO1
NCOA3
NCOA6
NCOR1
NR0B2
NR3C1
NRIP1
PPARA
RARA
RXRA
RXRB
RXRG
SIRT1
SRC
SS18L1
SUV39H1
SYT1
TMEM161A
ZXDC
Entrez ID
9857
10062
HPRD ID
09870
07211
Ensembl ID
ENSG00000135837
ENSG00000025434
Uniprot IDs
Q5VT06
B4DXU5
F1D8N1
Q13133
PDB IDs
2COZ
1UHL
3IPQ
3IPS
3IPU
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Cholesterol Storage
Steroid Hormone Mediated Signaling Pathway
Negative Regulation Of Macrophage Derived Foam Cell Differentiation
Regulation Of Receptor Biosynthetic Process
Negative Regulation Of Lipid Storage
Hormone-mediated Signaling Pathway
Positive Regulation Of Fatty Acid Metabolic Process
Transcription Initiation From RNA Polymerase II Promoter
Cellular Response To Steroid Hormone Stimulus
Intracellular Receptor Signaling Pathway
DNA-templated Transcription, Initiation
Regulation Of Macrophage Derived Foam Cell Differentiation
Regulation Of Lipid Storage
Fatty Acid Transport
Negative Regulation Of Collagen Biosynthetic Process
Negative Regulation Of Receptor Biosynthetic Process
Negative Regulation Of Interferon-gamma-mediated Signaling Pathway
Regulation Of Fatty Acid Metabolic Process
Negative Regulation Of Multicellular Organismal Metabolic Process
Cellular Response To Organic Cyclic Compound
Regulation Of Lipid Transport
Negative Regulation Of Sequestering Of Triglyceride
Regulation Of Circadian Rhythm
Cellular Response To Lipid
Negative Regulation Of Inflammatory Response
Response To Steroid Hormone
Monocarboxylic Acid Transport
Positive Regulation Of Fatty Acid Oxidation
Cellular Response To Hormone Stimulus
Regulation Of Interferon-gamma-mediated Signaling Pathway
Regulation Of Response To Interferon-gamma
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Response To Vitamin A
Regulation Of Fatty Acid Oxidation
Response To Lipid
Transcription From RNA Polymerase II Promoter
Response To Organic Cyclic Compound
Regulation Of Inflammatory Response
Regulation Of Collagen Metabolic Process
Response To Hormone
Regulation Of Cholesterol Transport
Negative Regulation Of Innate Immune Response
Negative Regulation Of Cytokine-mediated Signaling Pathway
Regulation Of Lipid Metabolic Process
Cellular Lipid Metabolic Process
Lipid Transport
Carboxylic Acid Transport
Organic Acid Transport
Negative Regulation Of Response To Cytokine Stimulus
Fatty Acid Metabolic Process
Intracellular Receptor Signaling Pathway
Positive Regulation Of Gene Expression
Positive Regulation Of Transcription, DNA-templated
Transcription Initiation From RNA Polymerase II Promoter
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of RNA Metabolic Process
Transcription, DNA-templated
RNA Biosynthetic Process
DNA-templated Transcription, Initiation
Regulation Of Transcription, DNA-templated
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Gene Expression
Positive Regulation Of Metabolic Process
Gene Expression
RNA Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Cellular Response To Steroid Hormone Stimulus
Regulation Of Metabolic Process
Steroid Hormone Mediated Signaling Pathway
Reproductive Structure Development
Reproductive System Development
Hormone-mediated Signaling Pathway
Intracellular Steroid Hormone Receptor Signaling Pathway
Response To Hormone
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Response To Hormone Stimulus
Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Transcription From RNA Polymerase II Promoter
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Developmental Process Involved In Reproduction
Organ Development
Cellular Nitrogen Compound Metabolic Process
Cellular Response To Organic Cyclic Compound
Retinoic Acid Receptor Signaling Pathway
Reproductive Process
Regulation Of Binding
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Tagcloud
?
abca1
abcg5
abcg8
atorvastatin
causal
challenging
chow
excised
fads1
gwas
hfd
hypertensive
list
loci
lpl
madd
nominally
orthologs
overlapped
pcsk9
pltp
qpcr
qtl
responded
spontaneously
stac3
staged
suggestive
timd4
Tagcloud (Difference)
?
abca1
abcg5
abcg8
atorvastatin
causal
challenging
chow
excised
fads1
gwas
hfd
hypertensive
list
loci
lpl
madd
nominally
orthologs
overlapped
pcsk9
pltp
qpcr
qtl
responded
spontaneously
stac3
staged
suggestive
timd4
Tagcloud (Intersection)
?