PLEKHA5 and WASH2P

Number of citations of the paper that reports this interaction (PMID 20936779)
48

Data Source:
BioGRID (two hybrid)

		PLEKHA5	WASH2P
Gene Name		pleckstrin homology domain containing, family A member 5	WAS protein family homolog 2 pseudogene
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Membrane
	Molecular Function	Protein Binding 1-phosphatidylinositol Binding Phosphatidylinositol-5-phosphate Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-4-phosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding
	Biological Process	Biological_process Reproductive System Development
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		30 interactors: ARHGEF9 BLOC1S6 CCDC186 CCDC88B CCDC92 CEP250 CEP350 DES EVPL EXTL3 KANSL1 KIF3A KRT19 KRT20 KTN1 LAMB2 LSM4 MAX PDZD11 PLEC PLEKHA6 PPP1R13B PROM1 SH3BP5L SOGA1 SPTAN1 SPTBN1 UPF1 WASH2P YWHAG	5 interactors: APP PLEKHA5 SNAP23 STAT5A TNFRSF21
Entrez ID		54477	375260
HPRD ID		09684	17562
Ensembl ID		ENSG00000052126	ENSG00000146556
Uniprot IDs		Q9HAU0
PDB IDs		2DKP
Enriched GO Terms of Interacting Partners?		Apoptotic Process Programmed Cell Death Cell Death Death Hemidesmosome Assembly Glomerular Visceral Epithelial Cell Differentiation Regulation Of Protein Complex Disassembly Cellular Localization Regulation Of Cellular Component Organization Movement Of Cell Or Subcellular Component Cellular Process Retina Development In Camera-type Eye Organelle Organization Generation Of Neurons Cell Differentiation Involved In Kidney Development Neuron Differentiation Cytoskeleton Organization Regulation Of Actin Filament Polymerization Microtubule-based Process Neurogenesis Metanephric Glomerular Basement Membrane Development Axon Extension Involved In Regeneration Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Cell-substrate Junction Assembly Actin Filament Capping Membrane Organization Regulation Of Cytoskeleton Organization Glomerulus Development Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Negative Regulation Of Actin Filament Depolymerization Epithelial Cell Differentiation Regulation Of Organelle Organization Metanephric Glomerular Visceral Epithelial Cell Development Response To Axon Injury Protein Localization Neuron Development Regulation Of Actin Filament Depolymerization Execution Phase Of Apoptosis Negative Regulation Of Actin Filament Polymerization Sensory Organ Development Glomerular Parietal Epithelial Cell Differentiation Positive Regulation Of Nephron Tubule Epithelial Cell Differentiation Regulation Of Centriole-centriole Cohesion Response To Insulin Establishment Of Localization In Cell Microtubule-based Movement Intracellular Transport Negative Regulation Of Protein Polymerization Post-Golgi Vesicle-mediated Transport	Neuron Apoptotic Process Neuron Death Regulation Of Multicellular Organism Growth Secretion Positive Regulation Of Mast Cell Differentiation Cell Activation Positive Regulation Of Mitotic Cell Cycle Immune System Process Regulation Of T Cell Proliferation Synaptic Growth At Neuromuscular Junction Oligodendrocyte Apoptotic Process Negative Regulation Of Interleukin-13 Secretion Negative Regulation Of Interleukin-5 Secretion Collateral Sprouting In Absence Of Injury Regulation Of Mast Cell Differentiation Negative Regulation Of Interleukin-10 Secretion Development Of Secondary Male Sexual Characteristics Negative Regulation Of Mast Cell Apoptotic Process Collateral Sprouting Axon Midline Choice Point Recognition Creatinine Metabolic Process Regulation Of Mast Cell Apoptotic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Interleukin-13 Production Positive Regulation Of Mast Cell Proliferation Isoleucine Metabolic Process Axon Choice Point Recognition Allantoin Metabolic Process Positive Regulation Of Cell Cycle Regulation Of Developmental Growth Lipid Metabolic Process Regulation Of T Cell Activation Immune Response Taurine Metabolic Process Positive Regulation Of Gamma-delta T Cell Differentiation Negative Regulation Of Interleukin-5 Production Glial Cell Apoptotic Process Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus Negative Regulation Of Erythrocyte Differentiation Prolactin Signaling Pathway B Cell Apoptotic Process Positive Regulation Of Gamma-delta T Cell Activation Neuron Remodeling Synaptic Vesicle Priming Development Of Secondary Female Sexual Characteristics Exocytosis Valine Metabolic Process Creatine Metabolic Process Negative Regulation Of Myelination Synaptic Vesicle Fusion To Presynaptic Membrane
Tagcloud ?		a375 a375br a375p aberrantly barrier bbb brain cerebrotropic constructed differentially extra homing immunofluorescence knock mediators melanoma metastases metastasis metastatic overwhelming parental passage profiles profiling propensity subjected transmigration viability yumul
Tagcloud (Difference) ?		a375 a375br a375p aberrantly barrier bbb brain cerebrotropic constructed differentially extra homing immunofluorescence knock mediators melanoma metastases metastasis metastatic overwhelming parental passage profiles profiling propensity subjected transmigration viability yumul
Tagcloud (Intersection) ?