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CEP350 and PPARD
Number of citations of the paper that reports this interaction (PMID
15615782
)
6
Data Source:
BioGRID
(pull down)
CEP350
PPARD
Gene Name
centrosomal protein 350kDa
peroxisome proliferator-activated receptor delta
Image
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Centrosome
Spindle
Membrane
Nucleus
Nucleoplasm
Molecular Function
Protein Binding
Microtubule Binding
DNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
Steroid Hormone Receptor Activity
Transcription Coactivator Activity
Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity
Protein Binding
Drug Binding
Zinc Ion Binding
Lipid Binding
Sequence-specific DNA Binding
NF-kappaB Binding
Linoleic Acid Binding
Biological Process
Microtubule Anchoring
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Glucose Metabolic Process
Proteoglycan Metabolic Process
Generation Of Precursor Metabolites And Energy
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Lipid Metabolic Process
Fatty Acid Beta-oxidation
Vitamin A Metabolic Process
Heart Development
Embryo Implantation
Cholesterol Metabolic Process
Cell Proliferation
Positive Regulation Of Cell Proliferation
Axon Ensheathment
Phospholipid Biosynthetic Process
Fatty Acid Catabolic Process
MRNA Transcription
Response To Glucose
Gene Expression
Positive Regulation Of Phosphatidylinositol 3-kinase Signaling
Response To Activity
Negative Regulation Of Smooth Muscle Cell Migration
Glucose Transport
Fatty Acid Transport
Cell Differentiation
Negative Regulation Of Cell Growth
Intracellular Receptor Signaling Pathway
Cell-substrate Adhesion
Positive Regulation Of Insulin Secretion
Negative Regulation Of Collagen Biosynthetic Process
Response To Vitamin A
Wound Healing
Negative Regulation Of Apoptotic Process
Steroid Hormone Mediated Signaling Pathway
Keratinocyte Proliferation
Positive Regulation Of Fat Cell Differentiation
Positive Regulation Of Epidermis Development
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Vasodilation
Decidualization
Negative Regulation Of Smooth Muscle Cell Proliferation
Negative Regulation Of Epithelial Cell Proliferation
Negative Regulation Of Inflammatory Response
Keratinocyte Migration
Adipose Tissue Development
Cellular Response To Hypoxia
Apoptotic Signaling Pathway
Pathways
Regulation of pyruvate dehydrogenase (PDH) complex
Pyruvate metabolism
Fatty acid, triacylglycerol, and ketone body metabolism
Metabolism of lipids and lipoproteins
Generic Transcription Pathway
Signaling by Retinoic Acid
Import of palmitoyl-CoA into the mitochondrial matrix
Pyruvate metabolism and Citric Acid (TCA) cycle
Nuclear Receptor transcription pathway
The citric acid (TCA) cycle and respiratory electron transport
Drugs
Icosapent
Treprostinil
Sulindac
Bezafibrate
Heptyl-Beta-D-Glucopyranoside
(11E)-OCTADEC-11-ENOIC ACID
(2S)-2-{3-[({[2-fluoro-4-(trifluoromethyl)phenyl]carbonyl}amino)methyl]-4-methoxybenzyl}butanoic acid
2-({[3-(3,4-dihydroisoquinolin-2(1H)-ylsulfonyl)phenyl]carbonyl}amino)benzoic acid
3-{5-methoxy-1-[(4-methoxyphenyl)sulfonyl]-1H-indol-3-yl}propanoic acid
{4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy}acetic acid
Diseases
GWAS
Anorexia nervosa (
23568457
)
Cataracts in type 2 diabetes (
23137000
)
Height (
21998595
)
Pulmonary function (interaction) (
23284291
)
Response to antipsychotic treatment (
20195266
)
Protein-Protein Interactions
6 interactors:
APTX
NR1H3
PLEKHA5
PPARA
PPARD
PPARG
39 interactors:
BCL6
CEP350
DUT
EIF3I
EP300
GADD45B
GADD45G
GLUL
HDAC1
HDAC2
HDAC3
HDAC4
HDAC7
HSP90AA1
ITGB5
KDM1A
KRTAP10-3
KRTAP10-7
NCOA1
NCOA2
NCOA3
NCOR1
NCOR2
NR0B2
NRIP1
PEBP1
PPARGC1A
PRDX6
PRMT3
PROX1
RANBP9
RXRA
RXRB
RXRG
SHMT2
SMAD9
SPEN
SRC
TNP1
Entrez ID
9857
5467
HPRD ID
09870
02679
Ensembl ID
ENSG00000135837
ENSG00000112033
Uniprot IDs
Q5VT06
F1D8S7
Q03181
PDB IDs
2COZ
1GWX
1Y0S
2AWH
2B50
2BAW
2ENV
2GWX
2J14
2Q5G
2XYJ
2XYW
2XYX
2ZNP
2ZNQ
3D5F
3DY6
3ET2
3GWX
3GZ9
3OZ0
3PEQ
3SP9
3TKM
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Cholesterol Storage
Steroid Hormone Mediated Signaling Pathway
Negative Regulation Of Macrophage Derived Foam Cell Differentiation
Regulation Of Receptor Biosynthetic Process
Negative Regulation Of Lipid Storage
Hormone-mediated Signaling Pathway
Positive Regulation Of Fatty Acid Metabolic Process
Transcription Initiation From RNA Polymerase II Promoter
Cellular Response To Steroid Hormone Stimulus
Intracellular Receptor Signaling Pathway
DNA-templated Transcription, Initiation
Regulation Of Macrophage Derived Foam Cell Differentiation
Regulation Of Lipid Storage
Fatty Acid Transport
Negative Regulation Of Collagen Biosynthetic Process
Negative Regulation Of Receptor Biosynthetic Process
Negative Regulation Of Interferon-gamma-mediated Signaling Pathway
Regulation Of Fatty Acid Metabolic Process
Negative Regulation Of Multicellular Organismal Metabolic Process
Cellular Response To Organic Cyclic Compound
Regulation Of Lipid Transport
Negative Regulation Of Sequestering Of Triglyceride
Regulation Of Circadian Rhythm
Cellular Response To Lipid
Negative Regulation Of Inflammatory Response
Response To Steroid Hormone
Monocarboxylic Acid Transport
Positive Regulation Of Fatty Acid Oxidation
Cellular Response To Hormone Stimulus
Regulation Of Interferon-gamma-mediated Signaling Pathway
Regulation Of Response To Interferon-gamma
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Response To Vitamin A
Regulation Of Fatty Acid Oxidation
Response To Lipid
Transcription From RNA Polymerase II Promoter
Response To Organic Cyclic Compound
Regulation Of Inflammatory Response
Regulation Of Collagen Metabolic Process
Response To Hormone
Regulation Of Cholesterol Transport
Negative Regulation Of Innate Immune Response
Negative Regulation Of Cytokine-mediated Signaling Pathway
Regulation Of Lipid Metabolic Process
Cellular Lipid Metabolic Process
Lipid Transport
Carboxylic Acid Transport
Organic Acid Transport
Negative Regulation Of Response To Cytokine Stimulus
Fatty Acid Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
Transcription, DNA-templated
Negative Regulation Of Gene Expression
Positive Regulation Of Gene Expression
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Biosynthetic Process
RNA Biosynthetic Process
Positive Regulation Of Cellular Biosynthetic Process
Rhythmic Process
Chromatin Organization
Positive Regulation Of Macromolecule Biosynthetic Process
Chromatin Modification
Positive Regulation Of Metabolic Process
Circadian Rhythm
Response To Organic Substance
Histone Modification
Cellular Macromolecule Biosynthetic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Macromolecule Biosynthetic Process
Intracellular Receptor Signaling Pathway
Circadian Regulation Of Gene Expression
Gene Expression
Regulation Of Transcription, DNA-templated
Histone H4 Deacetylation
Multicellular Organismal Development
Cellular Response To Organic Substance
Organelle Organization
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Biosynthetic Process
RNA Metabolic Process
Regulation Of Gene Expression
Regulation Of RNA Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Chromosome Organization
Developmental Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Transcription Initiation From RNA Polymerase II Promoter
Cell Differentiation
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Metabolic Process
Histone H3 Deacetylation
Tagcloud
?
almendro
birc5
casein
catenin
cd44
deregulate
distinguished
dvl1
ffpe
fzd7
gonen
ly294002
martins
mimicking
mmp7
modulators
notch1
pam50
park
pten
readout
subpopulation
sulfide
sulindac
tnbc
wp
xav939
zymograph
Tagcloud (Difference)
?
almendro
birc5
casein
catenin
cd44
deregulate
distinguished
dvl1
ffpe
fzd7
gonen
ly294002
martins
mimicking
mmp7
modulators
notch1
pam50
park
pten
readout
subpopulation
sulfide
sulindac
tnbc
wp
xav939
zymograph
Tagcloud (Intersection)
?